JKAMP (JNK1/MAPK8 associated membrane protein)

2014-11-01  

Identity

HGNC
JKAMP
LOCATION
14q23.1
LOCUSID
51528
ALIAS
C14orf100,C24orf100,CDA06,HSPC213,HSPC327,JAMP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51528
MIM: 611176
HGNC: 20184
Ensembl: ENSG00000050130

Variants:

dbSNP: 51528
ClinVar: 51528
TCGA: ENSG00000050130
COSMIC: JKAMP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000050130ENST00000356057Q9P055
ENSG00000050130ENST00000425728Q9P055
ENSG00000050130ENST00000554271G3V2M4
ENSG00000050130ENST00000554795G3V2R2
ENSG00000050130ENST00000555491G3V4D0
ENSG00000050130ENST00000556985G3V372
ENSG00000050130ENST00000616435Q9P055

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
192699662009Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP).17
237985712013Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.15
161666422005JAMP, a Jun N-terminal kinase 1 (JNK1)-associated membrane protein, regulates duration of JNK activity.9
187842502008JAMP optimizes ERAD to protect cells from unfolded proteins.8
251739652015Haematopoietic cell-derived Jnk1 is crucial for chronic inflammation and carcinogenesis in an experimental model of liver injury.7

Citation

Dessen P

JKAMP (JNK1/MAPK8 associated membrane protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64718/jkamp