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JMJD1C (jumonji domain containing 1C)

Identity

Alias_namesTRIP8
thyroid hormone receptor interactor 8
Alias_symbol (synonym)DKFZp761F0118
KIAA1380
FLJ14374
Other aliasKDM3C
TRIP-8
HGNC (Hugo) JMJD1C
LocusID (NCBI) 221037
Atlas_Id 47214
Location 10q21.3  [Link to chromosome band 10q21]
Location_base_pair Starts at 63167221 and ends at 63269223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ADSS (1q44) / JMJD1C (10q21.3)ATAD1 (10q23.31) / JMJD1C (10q21.3)HEBP2 (6q23.3) / JMJD1C (10q21.3)
JMJD1C (10q21.3) / ANK3 (10q21.2)JMJD1C (10q21.3) / ANKH (5p15.2)JMJD1C (10q21.3) / INO80 (15q15.1)
JMJD1C (10q21.3) / JMJD1C (10q21.3)JMJD1C (10q21.3) / NRBF2 (10q21.3)JMJD1C (10q21.3) / SEC31B (10q24.31)
JMJD1C (10q21.3) / TSN (2q14.3)MCU (10q22.1) / JMJD1C (10q21.3)SNRPD1 (18q11.2) / JMJD1C (10q21.3)
ATAD1 10q23.31 / JMJD1C 10q21.3JMJD1C 10q21.3 / ANK3 10q21.2JMJD1C 10q21.3 / NRBF2 10q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)JMJD1C   12313
Cards
Entrez_Gene (NCBI)JMJD1C  221037  jumonji domain containing 1C
AliasesKDM3C; TRIP-8; TRIP8
GeneCards (Weizmann)JMJD1C
Ensembl hg19 (Hinxton)ENSG00000171988 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171988 [Gene_View]  chr10:63167221-63269223 [Contig_View]  JMJD1C [Vega]
ICGC DataPortalENSG00000171988
TCGA cBioPortalJMJD1C
AceView (NCBI)JMJD1C
Genatlas (Paris)JMJD1C
WikiGenes221037
SOURCE (Princeton)JMJD1C
Genetics Home Reference (NIH)JMJD1C
Genomic and cartography
GoldenPath hg38 (UCSC)JMJD1C  -     chr10:63167221-63269223 -  10q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)JMJD1C  -     10q21.3   [Description]    (hg19-Feb_2009)
EnsemblJMJD1C - 10q21.3 [CytoView hg19]  JMJD1C - 10q21.3 [CytoView hg38]
Mapping of homologs : NCBIJMJD1C [Mapview hg19]  JMJD1C [Mapview hg38]
OMIM604503   
Gene and transcription
Genbank (Entrez)AB037801 AK024991 AK027280 AK056660 AK095584
RefSeq transcript (Entrez)NM_001282948 NM_001318153 NM_001318154 NM_001322252 NM_001322254 NM_001322258 NM_004241 NM_032776
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)JMJD1C
Cluster EST : UnigeneHs.413416 [ NCBI ]
CGAP (NCI)Hs.413416
Alternative Splicing GalleryENSG00000171988
Gene ExpressionJMJD1C [ NCBI-GEO ]   JMJD1C [ EBI - ARRAY_EXPRESS ]   JMJD1C [ SEEK ]   JMJD1C [ MEM ]
Gene Expression Viewer (FireBrowse)JMJD1C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)221037
GTEX Portal (Tissue expression)JMJD1C
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15652   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15652  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15652
Splice isoforms : SwissVarQ15652
Catalytic activity : Enzyme1.14.11.- [ Enzyme-Expasy ]   1.14.11.-1.14.11.- [ IntEnz-EBI ]   1.14.11.- [ BRENDA ]   1.14.11.- [ KEGG ]   
PhosPhoSitePlusQ15652
Domaine pattern : Prosite (Expaxy)JMJC (PS51184)   
Domains : Interpro (EBI)JmjC_dom   
Domain families : Pfam (Sanger)JmjC (PF02373)   
Domain families : Pfam (NCBI)pfam02373   
Domain families : Smart (EMBL)JmjC (SM00558)  
Conserved Domain (NCBI)JMJD1C
DMDM Disease mutations221037
Blocks (Seattle)JMJD1C
PDB (SRS)2YPD    5FZO   
PDB (PDBSum)2YPD    5FZO   
PDB (IMB)2YPD    5FZO   
PDB (RSDB)2YPD    5FZO   
Structural Biology KnowledgeBase2YPD    5FZO   
SCOP (Structural Classification of Proteins)2YPD    5FZO   
CATH (Classification of proteins structures)2YPD    5FZO   
SuperfamilyQ15652
Human Protein AtlasENSG00000171988
Peptide AtlasQ15652
HPRD05141
IPIIPI00384202   IPI00902772   IPI01012411   IPI01026089   IPI00641392   IPI00847837   
Protein Interaction databases
DIP (DOE-UCLA)Q15652
IntAct (EBI)Q15652
FunCoupENSG00000171988
BioGRIDJMJD1C
STRING (EMBL)JMJD1C
ZODIACJMJD1C
Ontologies - Pathways
QuickGOQ15652
Ontology : AmiGOchromatin  transcription regulatory region sequence-specific DNA binding  protein binding  intracellular  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  blood coagulation  chromatin DNA binding  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  metal ion binding  thyroid hormone receptor binding  dioxygenase activity  oxidation-reduction process  
Ontology : EGO-EBIchromatin  transcription regulatory region sequence-specific DNA binding  protein binding  intracellular  nucleus  nucleoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  blood coagulation  chromatin DNA binding  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  metal ion binding  thyroid hormone receptor binding  dioxygenase activity  oxidation-reduction process  
Pathways : KEGGTranscriptional misregulation in cancer   
NDEx NetworkJMJD1C
Atlas of Cancer Signalling NetworkJMJD1C
Wikipedia pathwaysJMJD1C
Orthology - Evolution
OrthoDB221037
GeneTree (enSembl)ENSG00000171988
Phylogenetic Trees/Animal Genes : TreeFamJMJD1C
HOVERGENQ15652
HOGENOMQ15652
Homologs : HomoloGeneJMJD1C
Homology/Alignments : Family Browser (UCSC)JMJD1C
Gene fusions - Rearrangements
Fusion : MitelmanATAD1/JMJD1C [10q23.31/10q21.3]  [t(10;10)(q21;q23)]  
Fusion : MitelmanJMJD1C/ANK3 [10q21.3/10q21.2]  [t(10;10)(q21;q21)]  
Fusion : MitelmanJMJD1C/NRBF2 [10q21.3/10q21.3]  [t(10;10)(q21;q21)]  
Fusion: TCGAATAD1 10q23.31 JMJD1C 10q21.3 PRAD
Fusion: TCGAJMJD1C 10q21.3 ANK3 10q21.2 PRAD
Fusion: TCGAJMJD1C 10q21.3 NRBF2 10q21.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerJMJD1C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)JMJD1C
dbVarJMJD1C
ClinVarJMJD1C
1000_GenomesJMJD1C 
Exome Variant ServerJMJD1C
ExAC (Exome Aggregation Consortium)JMJD1C (select the gene name)
Genetic variants : HAPMAP221037
Genomic Variants (DGV)JMJD1C [DGVbeta]
DECIPHERJMJD1C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisJMJD1C 
Mutations
ICGC Data PortalJMJD1C 
TCGA Data PortalJMJD1C 
Broad Tumor PortalJMJD1C
OASIS PortalJMJD1C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICJMJD1C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDJMJD1C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch JMJD1C
DgiDB (Drug Gene Interaction Database)JMJD1C
DoCM (Curated mutations)JMJD1C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)JMJD1C (select a term)
intoGenJMJD1C
Cancer3DJMJD1C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604503   
Orphanet126    12126   
MedgenJMJD1C
Genetic Testing Registry JMJD1C
NextProtQ15652 [Medical]
TSGene221037
GENETestsJMJD1C
Huge Navigator JMJD1C [HugePedia]
snp3D : Map Gene to Disease221037
BioCentury BCIQJMJD1C
ClinGenJMJD1C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD221037
Chemical/Pharm GKB GenePA128394767
Clinical trialJMJD1C
Miscellaneous
canSAR (ICR)JMJD1C (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineJMJD1C
EVEXJMJD1C
GoPubMedJMJD1C
iHOPJMJD1C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:21:02 CEST 2017

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