JRK (Jrk helix-turn-helix protein)

2017-10-01  

Identity

HGNC
JRK
LOCATION
8q24.3
LOCUSID
8629
ALIAS
JH8,jerky

Other Information

Locus ID:

NCBI: 8629
MIM: 603210
HGNC: 6199
Ensembl: ENSG00000234616

Variants:

dbSNP: 8629
ClinVar: 8629
TCGA: ENSG00000234616
COSMIC: JRK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000234616ENST00000503272A0A087WZD9
ENSG00000234616ENST00000571961O75564
ENSG00000234616ENST00000612905O75564
ENSG00000234616ENST00000614134O75564
ENSG00000234616ENST00000615982O75564

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
287088262017Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.10
264553212016JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.9

Citation

Dessen P

JRK (Jrk helix-turn-helix protein)

Atlas Genet Cytogenet Oncol Haematol. 2017-10-01

Online version: http://atlasgeneticsoncology.org/gene/57151/jrk