KANSL2 (KAT8 regulatory NSL complex subunit 2)

2014-11-01  

Identity

HGNC
KANSL2
LOCATION
12q13.11
LOCUSID
54934
ALIAS
C12orf41,NSL2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54934
MIM: 615488
HGNC: 26024
Ensembl: ENSG00000139620

Variants:

dbSNP: 54934
ClinVar: 54934
TCGA: ENSG00000139620
COSMIC: KANSL2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139620ENST00000420613Q9H9L4
ENSG00000139620ENST00000546701Q9H9L4
ENSG00000139620ENST00000546701A0A024R131
ENSG00000139620ENST00000547087H0YHR2
ENSG00000139620ENST00000547582H0YID1
ENSG00000139620ENST00000548147H0YHH4
ENSG00000139620ENST00000548304F8VP38
ENSG00000139620ENST00000549574H0YIQ8
ENSG00000139620ENST00000550347F8VX10
ENSG00000139620ENST00000550870F8VRX7
ENSG00000139620ENST00000550931F8VUX5
ENSG00000139620ENST00000553086F8VXI8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
274068302016The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.3

Citation

Dessen P

KANSL2 (KAT8 regulatory NSL complex subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64739/kansl2