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KAT2A (K(lysine) acetyltransferase 2A)

Identity

Other namesGCN5
GCN5L2
PCAF-b
hGCN5
HGNC (Hugo) KAT2A
LocusID (NCBI) 2648
Location 17q21.2
Location_base_pair Starts at 40265129 and ends at 40273382 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KAT2A   4201
Cards
Entrez_Gene (NCBI)KAT2A  2648  K(lysine) acetyltransferase 2A
GeneCards (Weizmann)KAT2A
Ensembl (Hinxton)ENSG00000108773 [Gene_View]  chr17:40265129-40273382 [Contig_View]  KAT2A [Vega]
ICGC DataPortalENSG00000108773
cBioPortalKAT2A
AceView (NCBI)KAT2A
Genatlas (Paris)KAT2A
WikiGenes2648
SOURCE (Princeton)NM_021078
Genomic and cartography
GoldenPath (UCSC)KAT2A  -  17q21.2   chr17:40265129-40273382 -  17q21.2   [Description]    (hg19-Feb_2009)
EnsemblKAT2A - 17q21.2 [CytoView]
Mapping of homologs : NCBIKAT2A [Mapview]
OMIM602301   
Gene and transcription
Genbank (Entrez)AF029777 BC032743 BC039907 BC105977 DB497139
RefSeq transcript (Entrez)NM_021078
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010783 NW_001838436 NW_004929407
Consensus coding sequences : CCDS (NCBI)KAT2A
Cluster EST : UnigeneHs.463045 [ NCBI ]
CGAP (NCI)Hs.463045
Alternative Splicing : Fast-db (Paris)GSHG0013413
Alternative Splicing GalleryENSG00000108773
Gene ExpressionKAT2A [ NCBI-GEO ]     KAT2A [ SEEK ]   KAT2A [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92830 (Uniprot)
NextProtQ92830  [Medical]
With graphics : InterProQ92830
Splice isoforms : SwissVarQ92830 (Swissvar)
Catalytic activity : Enzyme2.3.1.48 [ Enzyme-Expasy ]   2.3.1.482.3.1.48 [ IntEnz-EBI ]   2.3.1.48 [ BRENDA ]   2.3.1.48 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)    GNAT (PS51186)   
Domains : Interpro (EBI)Acyl_CoA_acyltransferase [organisation]   Bromodomain [organisation]   Bromodomain_CS [organisation]   GNAT_dom [organisation]   Hist_acetylase_PCAF [organisation]   PCAF_N [organisation]  
Related proteins : CluSTrQ92830
Domain families : Pfam (Sanger)Acetyltransf_1 (PF00583)    Bromodomain (PF00439)    PCAF_N (PF06466)   
Domain families : Pfam (NCBI)pfam00583    pfam00439    pfam06466   
Domain families : Smart (EMBL)BROMO (SM00297)  
DMDM Disease mutations2648
Blocks (Seattle)Q92830
PDB (SRS)1F68    1Z4R    3D7C   
PDB (PDBSum)1F68    1Z4R    3D7C   
PDB (IMB)1F68    1Z4R    3D7C   
PDB (RSDB)1F68    1Z4R    3D7C   
Human Protein AtlasENSG00000108773 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ92830
HPRD03807
IPIIPI00306871   IPI00221199   
Protein Interaction databases
DIP (DOE-UCLA)Q92830
IntAct (EBI)Q92830
FunCoupENSG00000108773
BioGRIDKAT2A
InParanoidQ92830
Interologous Interaction database Q92830
IntegromeDBKAT2A
STRING (EMBL)KAT2A
Ontologies - Pathways
Ontology : AmiGOin utero embryonic development  somitogenesis  neural tube closure  chromatin binding  transcription coactivator activity  histone acetyltransferase activity  histone acetyltransferase activity  protein binding  extracellular space  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  chromatin organization  chromatin remodeling  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  cell proliferation  H3 histone acetyltransferase activity  viral process  histone deubiquitination  telencephalon development  metencephalon development  midbrain development  STAGA complex  regulation of protein stability  transcription factor TFTC complex  multicellular organism growth  histone deacetylase binding  histone H3 acetylation  histone H4-K12 acetylation  histone acetyltransferase activity (H4-K12 specific)  histone H3-K14 acetylation  mitotic spindle  
Ontology : EGO-EBIin utero embryonic development  somitogenesis  neural tube closure  chromatin binding  transcription coactivator activity  histone acetyltransferase activity  histone acetyltransferase activity  protein binding  extracellular space  nucleoplasm  Ada2/Gcn5/Ada3 transcription activator complex  chromatin organization  chromatin remodeling  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  cell proliferation  H3 histone acetyltransferase activity  viral process  histone deubiquitination  telencephalon development  metencephalon development  midbrain development  STAGA complex  regulation of protein stability  transcription factor TFTC complex  multicellular organism growth  histone deacetylase binding  histone H3 acetylation  histone H4-K12 acetylation  histone acetyltransferase activity (H4-K12 specific)  histone H3-K14 acetylation  mitotic spindle  
Pathways : KEGGNotch signaling pathway    Thyroid hormone signaling pathway    HTLV-I infection    Viral carcinogenesis   
Protein Interaction DatabaseKAT2A
Wikipedia pathwaysKAT2A
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)KAT2A
snp3D : Map Gene to Disease2648
SNP (GeneSNP Utah)KAT2A
SNP : HGBaseKAT2A
Genetic variants : HAPMAPKAT2A
Exome VariantKAT2A
1000_GenomesKAT2A 
ICGC programENSG00000108773 
Somatic Mutations in Cancer : COSMICKAT2A 
CONAN: Copy Number AnalysisKAT2A 
Mutations and Diseases : HGMDKAT2A
Mutations and Diseases : intOGenKAT2A
Genomic VariantsKAT2A  KAT2A [DGVbeta]
dbVarKAT2A
ClinVarKAT2A
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602301   
MedgenKAT2A
GENETestsKAT2A
Disease Genetic AssociationKAT2A
Huge Navigator KAT2A [HugePedia]  KAT2A [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneKAT2A
Homology/Alignments : Family Browser (UCSC)KAT2A
Phylogenetic Trees/Animal Genes : TreeFamKAT2A
Chemical/Protein Interactions : CTD2648
Chemical/Pharm GKB GenePA162392664
Clinical trialKAT2A
Cancer Resource (Charite)ENSG00000108773
Other databases
Probes
Litterature
PubMed107 Pubmed reference(s) in Entrez
CoreMineKAT2A
iHOPKAT2A
OncoSearchKAT2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:57:42 CEST 2014

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