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KBTBD8 (kelch repeat and BTB domain containing 8)

Identity

Alias (NCBI)TA-KRP
TAKRP
HGNC (Hugo) KBTBD8
HGNC Alias symbTA-KRP
KIAA1842
HGNC Alias nameT-cell activation kelch repeat protein
HGNC Previous namekelch repeat and BTB (POZ) domain containing 8
LocusID (NCBI) 84541
Atlas_Id 64755
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 66998307 and ends at 67011208 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NOVA1 (14q12) / KBTBD8 (3p14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KBTBD8   30691
Cards
Entrez_Gene (NCBI)KBTBD8    kelch repeat and BTB domain containing 8
AliasesTA-KRP; TAKRP
GeneCards (Weizmann)KBTBD8
Ensembl hg19 (Hinxton)ENSG00000163376 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163376 [Gene_View]  ENSG00000163376 [Sequence]  chr3:66998307-67011208 [Contig_View]  KBTBD8 [Vega]
ICGC DataPortalENSG00000163376
TCGA cBioPortalKBTBD8
AceView (NCBI)KBTBD8
Genatlas (Paris)KBTBD8
SOURCE (Princeton)KBTBD8
Genetics Home Reference (NIH)KBTBD8
Genomic and cartography
GoldenPath hg38 (UCSC)KBTBD8  -     chr3:66998307-67011208 +  3p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KBTBD8  -     3p14.1   [Description]    (hg19-Feb_2009)
GoldenPathKBTBD8 - 3p14.1 [CytoView hg19]  KBTBD8 - 3p14.1 [CytoView hg38]
ImmunoBaseENSG00000163376
Genome Data Viewer NCBIKBTBD8 [Mapview hg19]  
OMIM616607   
Gene and transcription
Genbank (Entrez)AB058745 AF385438 AK096640 AK300397 BC117487
RefSeq transcript (Entrez)NM_032505
Consensus coding sequences : CCDS (NCBI)KBTBD8
Gene ExpressionKBTBD8 [ NCBI-GEO ]   KBTBD8 [ EBI - ARRAY_EXPRESS ]   KBTBD8 [ SEEK ]   KBTBD8 [ MEM ]
Gene Expression Viewer (FireBrowse)KBTBD8 [ Firebrowse - Broad ]
GenevisibleExpression of KBTBD8 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84541
GTEX Portal (Tissue expression)KBTBD8
Human Protein AtlasENSG00000163376-KBTBD8 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFY9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFY9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFY9
PhosPhoSitePlusQ8NFY9
Domaine pattern : Prosite (Expaxy)BTB (PS50097)   
Domains : Interpro (EBI)BACK    BTB-kelch_protein    BTB/POZ_dom    KBTBD8    Kelch-typ_b-propeller    Kelch_1    SKP1/BTB/POZ_sf   
Domain families : Pfam (Sanger)BACK (PF07707)    BTB (PF00651)    Kelch_1 (PF01344)   
Domain families : Pfam (NCBI)pfam07707    pfam00651    pfam01344   
Domain families : Smart (EMBL)BACK (SM00875)  BTB (SM00225)  Kelch (SM00612)  
Conserved Domain (NCBI)KBTBD8
SuperfamilyQ8NFY9
AlphaFold pdb e-kbQ8NFY9   
Human Protein Atlas [tissue]ENSG00000163376-KBTBD8 [tissue]
HPRD18138
Protein Interaction databases
DIP (DOE-UCLA)Q8NFY9
IntAct (EBI)Q8NFY9
BioGRIDKBTBD8
STRING (EMBL)KBTBD8
ZODIACKBTBD8
Ontologies - Pathways
QuickGOQ8NFY9
Ontology : AmiGOprotein binding  Golgi apparatus  spindle  cytosol  regulation of translation  protein monoubiquitination  neural crest formation  neural crest cell development  Cul3-RING ubiquitin ligase complex  post-translational protein modification  
Ontology : EGO-EBIprotein binding  Golgi apparatus  spindle  cytosol  regulation of translation  protein monoubiquitination  neural crest formation  neural crest cell development  Cul3-RING ubiquitin ligase complex  post-translational protein modification  
NDEx NetworkKBTBD8
Atlas of Cancer Signalling NetworkKBTBD8
Wikipedia pathwaysKBTBD8
Orthology - Evolution
OrthoDB84541
GeneTree (enSembl)ENSG00000163376
Phylogenetic Trees/Animal Genes : TreeFamKBTBD8
Homologs : HomoloGeneKBTBD8
Homology/Alignments : Family Browser (UCSC)KBTBD8
Gene fusions - Rearrangements
Fusion : QuiverKBTBD8
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKBTBD8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KBTBD8
dbVarKBTBD8
ClinVarKBTBD8
MonarchKBTBD8
1000_GenomesKBTBD8 
Exome Variant ServerKBTBD8
GNOMAD BrowserENSG00000163376
Varsome BrowserKBTBD8
ACMGKBTBD8 variants
VarityQ8NFY9
Genomic Variants (DGV)KBTBD8 [DGVbeta]
DECIPHERKBTBD8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKBTBD8 
Mutations
ICGC Data PortalKBTBD8 
TCGA Data PortalKBTBD8 
Broad Tumor PortalKBTBD8
OASIS PortalKBTBD8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKBTBD8  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKBTBD8
Mutations and Diseases : HGMDKBTBD8
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKBTBD8
DgiDB (Drug Gene Interaction Database)KBTBD8
DoCM (Curated mutations)KBTBD8
CIViC (Clinical Interpretations of Variants in Cancer)KBTBD8
Cancer3DKBTBD8
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616607   
Orphanet
DisGeNETKBTBD8
MedgenKBTBD8
Genetic Testing Registry KBTBD8
NextProtQ8NFY9 [Medical]
GENETestsKBTBD8
Target ValidationKBTBD8
Huge Navigator KBTBD8 [HugePedia]
ClinGenKBTBD8
Clinical trials, drugs, therapy
MyCancerGenomeKBTBD8
Protein Interactions : CTDKBTBD8
Pharm GKB GenePA142671641
PharosQ8NFY9
Clinical trialKBTBD8
Miscellaneous
canSAR (ICR)KBTBD8
HarmonizomeKBTBD8
DataMed IndexKBTBD8
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKBTBD8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:54:14 CEST 2021

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