Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNA6 (potassium voltage-gated channel subfamily A member 6)

Identity

Alias_namesregulatory subunit 96
Alias_symbol (synonym)Kv1.6
HBK2
PPP1R96
Other aliasKV1.6
HGNC (Hugo) KCNA6
LocusID (NCBI) 3742
Atlas_Id 50159
Location 12p13.32  [Link to chromosome band 12p13]
Location_base_pair Starts at 4809176 and ends at 4851112 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ZNF804B (7q21.13) / KCNA6 (12p13.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNA6   6225
Cards
Entrez_Gene (NCBI)KCNA6  3742  potassium voltage-gated channel subfamily A member 6
AliasesHBK2; KV1.6; PPP1R96
GeneCards (Weizmann)KCNA6
Ensembl hg19 (Hinxton)ENSG00000130035 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130035 [Gene_View]  chr12:4809176-4851112 [Contig_View]  KCNA6 [Vega]
ICGC DataPortalENSG00000130035
TCGA cBioPortalKCNA6
AceView (NCBI)KCNA6
Genatlas (Paris)KCNA6
WikiGenes3742
SOURCE (Princeton)KCNA6
Genetics Home Reference (NIH)KCNA6
Genomic and cartography
GoldenPath hg38 (UCSC)KCNA6  -     chr12:4809176-4851112 +  12p13.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNA6  -     12p13.32   [Description]    (hg19-Feb_2009)
EnsemblKCNA6 - 12p13.32 [CytoView hg19]  KCNA6 - 12p13.32 [CytoView hg38]
Mapping of homologs : NCBIKCNA6 [Mapview hg19]  KCNA6 [Mapview hg38]
OMIM176257   
Gene and transcription
Genbank (Entrez)AI369246 AK057863 BC069355 HQ447440 X17622
RefSeq transcript (Entrez)NM_002235
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNA6
Cluster EST : UnigeneHs.306190 [ NCBI ]
CGAP (NCI)Hs.306190
Alternative Splicing GalleryENSG00000130035
Gene ExpressionKCNA6 [ NCBI-GEO ]   KCNA6 [ EBI - ARRAY_EXPRESS ]   KCNA6 [ SEEK ]   KCNA6 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNA6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3742
GTEX Portal (Tissue expression)KCNA6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP17658   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP17658  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP17658
Splice isoforms : SwissVarP17658
PhosPhoSitePlusP17658
Domains : Interpro (EBI)BTB/POZ_dom    Channel_four-helix_dom    Ion_trans_dom    K_chnl_volt-dep_Kv    K_chnl_volt-dep_Kv1    K_chnl_volt-dep_Kv1.6    SKP1/BTB/POZ    T1-type_BTB    VG_K_chnl   
Domain families : Pfam (Sanger)BTB_2 (PF02214)    Ion_trans (PF00520)   
Domain families : Pfam (NCBI)pfam02214    pfam00520   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCNA6
DMDM Disease mutations3742
Blocks (Seattle)KCNA6
SuperfamilyP17658
Human Protein AtlasENSG00000130035
Peptide AtlasP17658
HPRD08884
IPIIPI00015931   
Protein Interaction databases
DIP (DOE-UCLA)P17658
IntAct (EBI)P17658
FunCoupENSG00000130035
BioGRIDKCNA6
STRING (EMBL)KCNA6
ZODIACKCNA6
Ontologies - Pathways
QuickGOP17658
Ontology : AmiGOvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  potassium ion transport  voltage-gated potassium channel complex  axon  potassium channel complex  regulation of ion transmembrane transport  axon terminus  protein homooligomerization  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  potassium ion transport  voltage-gated potassium channel complex  axon  potassium channel complex  regulation of ion transmembrane transport  axon terminus  protein homooligomerization  potassium ion transmembrane transport  
NDEx NetworkKCNA6
Atlas of Cancer Signalling NetworkKCNA6
Wikipedia pathwaysKCNA6
Orthology - Evolution
OrthoDB3742
GeneTree (enSembl)ENSG00000130035
Phylogenetic Trees/Animal Genes : TreeFamKCNA6
HOVERGENP17658
HOGENOMP17658
Homologs : HomoloGeneKCNA6
Homology/Alignments : Family Browser (UCSC)KCNA6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNA6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNA6
dbVarKCNA6
ClinVarKCNA6
1000_GenomesKCNA6 
Exome Variant ServerKCNA6
ExAC (Exome Aggregation Consortium)KCNA6 (select the gene name)
Genetic variants : HAPMAP3742
Genomic Variants (DGV)KCNA6 [DGVbeta]
DECIPHERKCNA6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNA6 
Mutations
ICGC Data PortalKCNA6 
TCGA Data PortalKCNA6 
Broad Tumor PortalKCNA6
OASIS PortalKCNA6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNA6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNA6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNA6
DgiDB (Drug Gene Interaction Database)KCNA6
DoCM (Curated mutations)KCNA6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNA6 (select a term)
intoGenKCNA6
Cancer3DKCNA6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176257   
Orphanet
MedgenKCNA6
Genetic Testing Registry KCNA6
NextProtP17658 [Medical]
TSGene3742
GENETestsKCNA6
Huge Navigator KCNA6 [HugePedia]
snp3D : Map Gene to Disease3742
BioCentury BCIQKCNA6
ClinGenKCNA6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3742
Chemical/Pharm GKB GenePA30022
Clinical trialKCNA6
Miscellaneous
canSAR (ICR)KCNA6 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNA6
EVEXKCNA6
GoPubMedKCNA6
iHOPKCNA6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:21:09 CEST 2017

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