Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNAB1 (potassium channel, voltage gated subfamily A regulatory beta subunit 1)

Identity

Alias_namespotassium voltage-gated channel, shaker-related subfamily, beta member 1
Alias_symbol (synonym)AKR6A3
KCNA1B
hKvBeta3
Kvb1.3
hKvb3
Other aliasKV-BETA-1
HGNC (Hugo) KCNAB1
LocusID (NCBI) 7881
Atlas_Id 64759
Location 3q25.31  [Link to chromosome band 3q25]
Location_base_pair Starts at 155838337 and ends at 156256541 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ERBB4 (2q34) / KCNAB1 (3q25.31)HLA-DRB1 (6p21.32) / KCNAB1 (3q25.31)KCNAB1 (3q25.31) / HNRNPUL2 (11q12.3)
KCNAB1 (3q25.31) / TCF7L1 (2p11.2)MLLT4 (6q27) / KCNAB1 (3q25.31)PHLDB2 (3q13.2) / KCNAB1 (3q25.31)
PIK3CB (3q22.3) / KCNAB1 (3q25.31)SLC9A9 (3q24) / KCNAB1 (3q25.31)MLLT4 KCNAB1
PIK3CB KCNAB1SLC9A9 KCNAB1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNAB1   6228
Cards
Entrez_Gene (NCBI)KCNAB1  7881  potassium channel, voltage gated subfamily A regulatory beta subunit 1
AliasesAKR6A3; KCNA1B; KV-BETA-1; Kvb1.3; 
hKvBeta3; hKvb3
GeneCards (Weizmann)KCNAB1
Ensembl hg19 (Hinxton)ENSG00000169282 [Gene_View]  chr3:155838337-156256541 [Contig_View]  KCNAB1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000169282 [Gene_View]  chr3:155838337-156256541 [Contig_View]  KCNAB1 [Vega]
ICGC DataPortalENSG00000169282
TCGA cBioPortalKCNAB1
AceView (NCBI)KCNAB1
Genatlas (Paris)KCNAB1
WikiGenes7881
SOURCE (Princeton)KCNAB1
Genetics Home Reference (NIH)KCNAB1
Genomic and cartography
GoldenPath hg19 (UCSC)KCNAB1  -     chr3:155838337-156256541 +  3q25.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNAB1  -     3q25.31   [Description]    (hg38-Dec_2013)
EnsemblKCNAB1 - 3q25.31 [CytoView hg19]  KCNAB1 - 3q25.31 [CytoView hg38]
Mapping of homologs : NCBIKCNAB1 [Mapview hg19]  KCNAB1 [Mapview hg38]
OMIM601141   
Gene and transcription
Genbank (Entrez)AI344124 AK057059 AK127240 AK292693 AK292999
RefSeq transcript (Entrez)NM_001308217 NM_001308222 NM_003471 NM_172159 NM_172160
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_005612 NW_004929311
Consensus coding sequences : CCDS (NCBI)KCNAB1
Cluster EST : UnigeneHs.703187 [ NCBI ]
CGAP (NCI)Hs.703187
Alternative Splicing GalleryENSG00000169282
Gene ExpressionKCNAB1 [ NCBI-GEO ]   KCNAB1 [ EBI - ARRAY_EXPRESS ]   KCNAB1 [ SEEK ]   KCNAB1 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNAB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7881
GTEX Portal (Tissue expression)KCNAB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14722   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14722  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14722
Splice isoforms : SwissVarQ14722
PhosPhoSitePlusQ14722
Domains : Interpro (EBI)Aldo/ket_red    K_chnl_volt-dep_bsu_KCNAB    K_chnl_volt-dep_bsu_KCNAB-rel    K_chnl_volt-dep_bsu_KCNAB1    NADP_OxRdtase_dom   
Domain families : Pfam (Sanger)Aldo_ket_red (PF00248)   
Domain families : Pfam (NCBI)pfam00248   
Conserved Domain (NCBI)KCNAB1
DMDM Disease mutations7881
Blocks (Seattle)KCNAB1
SuperfamilyQ14722
Human Protein AtlasENSG00000169282
Peptide AtlasQ14722
HPRD03089
IPIIPI00783784   IPI00221124   IPI00783814   IPI00947184   IPI00033023   IPI00947028   IPI00944894   IPI00946321   
Protein Interaction databases
DIP (DOE-UCLA)Q14722
IntAct (EBI)Q14722
FunCoupENSG00000169282
BioGRIDKCNAB1
STRING (EMBL)KCNAB1
ZODIACKCNAB1
Ontologies - Pathways
QuickGOQ14722
Ontology : AmiGOaldo-keto reductase (NADP) activity  voltage-gated potassium channel activity  cytosol  plasma membrane  potassium ion transport  synaptic transmission  learning or memory  potassium channel regulator activity  extrinsic component of cytoplasmic side of plasma membrane  potassium channel complex  oxidation-reduction process  NADPH binding  potassium ion transmembrane transport  regulation of potassium ion transmembrane transport  regulation of delayed rectifier potassium channel activity  
Ontology : EGO-EBIaldo-keto reductase (NADP) activity  voltage-gated potassium channel activity  cytosol  plasma membrane  potassium ion transport  synaptic transmission  learning or memory  potassium channel regulator activity  extrinsic component of cytoplasmic side of plasma membrane  potassium channel complex  oxidation-reduction process  NADPH binding  potassium ion transmembrane transport  regulation of potassium ion transmembrane transport  regulation of delayed rectifier potassium channel activity  
NDEx NetworkKCNAB1
Atlas of Cancer Signalling NetworkKCNAB1
Wikipedia pathwaysKCNAB1
Orthology - Evolution
OrthoDB7881
GeneTree (enSembl)ENSG00000169282
Phylogenetic Trees/Animal Genes : TreeFamKCNAB1
HOVERGENQ14722
HOGENOMQ14722
Homologs : HomoloGeneKCNAB1
Homology/Alignments : Family Browser (UCSC)KCNAB1
Gene fusions - Rearrangements
Fusion: TCGAMLLT4 KCNAB1
Fusion: TCGAPIK3CB KCNAB1
Fusion: TCGASLC9A9 KCNAB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNAB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNAB1
dbVarKCNAB1
ClinVarKCNAB1
1000_GenomesKCNAB1 
Exome Variant ServerKCNAB1
ExAC (Exome Aggregation Consortium)KCNAB1 (select the gene name)
Genetic variants : HAPMAP7881
Genomic Variants (DGV)KCNAB1 [DGVbeta]
DECIPHER (Syndromes)3:155838337-156256541  ENSG00000169282
CONAN: Copy Number AnalysisKCNAB1 
Mutations
ICGC Data PortalKCNAB1 
TCGA Data PortalKCNAB1 
Broad Tumor PortalKCNAB1
OASIS PortalKCNAB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNAB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNAB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNAB1
DgiDB (Drug Gene Interaction Database)KCNAB1
DoCM (Curated mutations)KCNAB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNAB1 (select a term)
intoGenKCNAB1
Cancer3DKCNAB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601141   
Orphanet
MedgenKCNAB1
Genetic Testing Registry KCNAB1
NextProtQ14722 [Medical]
TSGene7881
GENETestsKCNAB1
Huge Navigator KCNAB1 [HugePedia]
snp3D : Map Gene to Disease7881
BioCentury BCIQKCNAB1
ClinGenKCNAB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7881
Chemical/Pharm GKB GenePA370
Clinical trialKCNAB1
Miscellaneous
canSAR (ICR)KCNAB1 (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNAB1
EVEXKCNAB1
GoPubMedKCNAB1
iHOPKCNAB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 12:09:20 CET 2017

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