KCNB2 (potassium voltage-gated channel subfamily B member 2)

2014-11-01 Affiliation

Identity

HGNC

KCNB2

LOCATION

8q21.11

LOCUSID

9312

ALIAS

KV2.2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9312
MIM: 607738
HGNC: 6232
Ensembl: ENSG00000182674

Variants:

dbSNP: 9312
ClinVar: 9312
TCGA: ENSG00000182674
COSMIC: KCNB2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000182674	ENST00000523207	Q92953

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Neuronal System	REACTOME	R-HSA-112316
Potassium Channels	REACTOME	R-HSA-1296071
Voltage gated Potassium channels	REACTOME	R-HSA-1296072

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
17903301	2007	Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.	50
18676988	2008	A high-density association screen of 155 ion transport genes for involvement with common migraine.	22
23953852	2013	Genome-wide association studies of maximum number of drinks.	22
25339316	2014	Disease-targeted sequencing of ion channel genes identifies de novo mutations in patients with non-familial Brugada syndrome.	16
22422395	2012	Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.	12
28607108	2017	Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.	8

Citation

Dessen P

KCNB2 (potassium voltage-gated channel subfamily B member 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64765/kcnb2