Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNC1 (potassium voltage-gated channel subfamily C member 1)

Identity

Alias_namespotassium voltage-gated channel, Shaw-related subfamily, member 1
potassium channel, voltage gated Shaw related subfamily C, member 1
Alias_symbol (synonym)Kv3.1
Other aliasEPM7
KV3.1
KV4
NGK2
HGNC (Hugo) KCNC1
LocusID (NCBI) 3746
Atlas_Id 64766
Location 11p15.1  [Link to chromosome band 11p15]
Location_base_pair Starts at 17735948 and ends at 17783055 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNC1   6233
Cards
Entrez_Gene (NCBI)KCNC1  3746  potassium voltage-gated channel subfamily C member 1
AliasesEPM7; KV3.1; KV4; NGK2
GeneCards (Weizmann)KCNC1
Ensembl hg19 (Hinxton)ENSG00000129159 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000129159 [Gene_View]  chr11:17735948-17783055 [Contig_View]  KCNC1 [Vega]
ICGC DataPortalENSG00000129159
TCGA cBioPortalKCNC1
AceView (NCBI)KCNC1
Genatlas (Paris)KCNC1
WikiGenes3746
SOURCE (Princeton)KCNC1
Genetics Home Reference (NIH)KCNC1
Genomic and cartography
GoldenPath hg38 (UCSC)KCNC1  -     chr11:17735948-17783055 +  11p15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNC1  -     11p15.1   [Description]    (hg19-Feb_2009)
EnsemblKCNC1 - 11p15.1 [CytoView hg19]  KCNC1 - 11p15.1 [CytoView hg38]
Mapping of homologs : NCBIKCNC1 [Mapview hg19]  KCNC1 [Mapview hg38]
OMIM176258   616187   
Gene and transcription
Genbank (Entrez)AI201688 AK123157 AK124243 AK125480 AW452561
RefSeq transcript (Entrez)NM_001112741 NM_004976
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNC1
Cluster EST : UnigeneHs.552896 [ NCBI ]
CGAP (NCI)Hs.552896
Alternative Splicing GalleryENSG00000129159
Gene ExpressionKCNC1 [ NCBI-GEO ]   KCNC1 [ EBI - ARRAY_EXPRESS ]   KCNC1 [ SEEK ]   KCNC1 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3746
GTEX Portal (Tissue expression)KCNC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP48547   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP48547  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP48547
Splice isoforms : SwissVarP48547
PhosPhoSitePlusP48547
Domains : Interpro (EBI)BTB/POZ_dom    Channel_four-helix_dom    Ion_trans_dom    K_chnl_volt-dep_Kv    K_chnl_volt-dep_Kv3    K_chnl_volt-dep_Kv3.1    SKP1/BTB/POZ    T1-type_BTB    VG_K_chnl   
Domain families : Pfam (Sanger)BTB_2 (PF02214)    Ion_trans (PF00520)   
Domain families : Pfam (NCBI)pfam02214    pfam00520   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCNC1
DMDM Disease mutations3746
Blocks (Seattle)KCNC1
SuperfamilyP48547
Human Protein AtlasENSG00000129159
Peptide AtlasP48547
HPRD15936
IPIIPI00010174   IPI00976366   IPI00879694   
Protein Interaction databases
DIP (DOE-UCLA)P48547
IntAct (EBI)P48547
FunCoupENSG00000129159
BioGRIDKCNC1
STRING (EMBL)KCNC1
ZODIACKCNC1
Ontologies - Pathways
QuickGOP48547
Ontology : AmiGOvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  plasma membrane  potassium ion transport  voltage-gated potassium channel complex  voltage-gated potassium channel complex  response to toxic substance  response to light intensity  cell surface  response to auditory stimulus  response to amine  kinesin binding  cerebellum development  globus pallidus development  dendrite  axolemma  dendrite membrane  neuronal cell body membrane  cellular response to drug  response to potassium ion  ion channel binding  protein homooligomerization  protein tetramerization  response to fibroblast growth factor  potassium ion transmembrane transport  positive regulation of potassium ion transmembrane transport  response to nerve growth factor  
Ontology : EGO-EBIvoltage-gated potassium channel activity  delayed rectifier potassium channel activity  plasma membrane  potassium ion transport  voltage-gated potassium channel complex  voltage-gated potassium channel complex  response to toxic substance  response to light intensity  cell surface  response to auditory stimulus  response to amine  kinesin binding  cerebellum development  globus pallidus development  dendrite  axolemma  dendrite membrane  neuronal cell body membrane  cellular response to drug  response to potassium ion  ion channel binding  protein homooligomerization  protein tetramerization  response to fibroblast growth factor  potassium ion transmembrane transport  positive regulation of potassium ion transmembrane transport  response to nerve growth factor  
NDEx NetworkKCNC1
Atlas of Cancer Signalling NetworkKCNC1
Wikipedia pathwaysKCNC1
Orthology - Evolution
OrthoDB3746
GeneTree (enSembl)ENSG00000129159
Phylogenetic Trees/Animal Genes : TreeFamKCNC1
HOVERGENP48547
HOGENOMP48547
Homologs : HomoloGeneKCNC1
Homology/Alignments : Family Browser (UCSC)KCNC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNC1
dbVarKCNC1
ClinVarKCNC1
1000_GenomesKCNC1 
Exome Variant ServerKCNC1
ExAC (Exome Aggregation Consortium)KCNC1 (select the gene name)
Genetic variants : HAPMAP3746
Genomic Variants (DGV)KCNC1 [DGVbeta]
DECIPHERKCNC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNC1 
Mutations
ICGC Data PortalKCNC1 
TCGA Data PortalKCNC1 
Broad Tumor PortalKCNC1
OASIS PortalKCNC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNC1
DgiDB (Drug Gene Interaction Database)KCNC1
DoCM (Curated mutations)KCNC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNC1 (select a term)
intoGenKCNC1
Cancer3DKCNC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176258    616187   
Orphanet23295   
MedgenKCNC1
Genetic Testing Registry KCNC1
NextProtP48547 [Medical]
TSGene3746
GENETestsKCNC1
Target ValidationKCNC1
Huge Navigator KCNC1 [HugePedia]
snp3D : Map Gene to Disease3746
BioCentury BCIQKCNC1
ClinGenKCNC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3746
Chemical/Pharm GKB GenePA30026
Clinical trialKCNC1
Miscellaneous
canSAR (ICR)KCNC1 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNC1
EVEXKCNC1
GoPubMedKCNC1
iHOPKCNC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:11:34 CEST 2017

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