Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNC2 (potassium voltage-gated channel subfamily C member 2)

Identity

Alias_namespotassium voltage-gated channel, Shaw-related subfamily, member 2
potassium channel, voltage gated Shaw related subfamily C, member 2
Alias_symbol (synonym)Kv3.2
Other aliasKV3.2
HGNC (Hugo) KCNC2
LocusID (NCBI) 3747
Atlas_Id 64767
Location 12q21.1  [Link to chromosome band 12q21]
Location_base_pair Starts at 75040078 and ends at 75209748 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP2B1 (12q21.33) / KCNC2 (12q21.1)KCNC2 (12q21.1) / CAPS2 (12q21.1)MARCH9 (12q14.1) / KCNC2 (12q21.1)
ROR2 (9q22.31) / KCNC2 (12q21.1)MARCH9 KCNC2ROR2 KCNC2
ATP2B1 KCNC2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNC2   6234
Cards
Entrez_Gene (NCBI)KCNC2  3747  potassium voltage-gated channel subfamily C member 2
AliasesKV3.2
GeneCards (Weizmann)KCNC2
Ensembl hg19 (Hinxton)ENSG00000166006 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166006 [Gene_View]  chr12:75040078-75209748 [Contig_View]  KCNC2 [Vega]
ICGC DataPortalENSG00000166006
TCGA cBioPortalKCNC2
AceView (NCBI)KCNC2
Genatlas (Paris)KCNC2
WikiGenes3747
SOURCE (Princeton)KCNC2
Genetics Home Reference (NIH)KCNC2
Genomic and cartography
GoldenPath hg38 (UCSC)KCNC2  -     chr12:75040078-75209748 -  12q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNC2  -     12q21.1   [Description]    (hg19-Feb_2009)
EnsemblKCNC2 - 12q21.1 [CytoView hg19]  KCNC2 - 12q21.1 [CytoView hg38]
Mapping of homologs : NCBIKCNC2 [Mapview hg19]  KCNC2 [Mapview hg38]
OMIM176256   
Gene and transcription
Genbank (Entrez)AB209994 AF268896 AF268897 AK094720 AK126235
RefSeq transcript (Entrez)NM_001260497 NM_001260498 NM_001260499 NM_139136 NM_139137 NM_153748
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNC2
Cluster EST : UnigeneHs.741918 [ NCBI ]
CGAP (NCI)Hs.741918
Alternative Splicing GalleryENSG00000166006
Gene ExpressionKCNC2 [ NCBI-GEO ]   KCNC2 [ EBI - ARRAY_EXPRESS ]   KCNC2 [ SEEK ]   KCNC2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNC2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3747
GTEX Portal (Tissue expression)KCNC2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96PR1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96PR1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96PR1
Splice isoforms : SwissVarQ96PR1
PhosPhoSitePlusQ96PR1
Domains : Interpro (EBI)BTB/POZ_dom    Channel_four-helix_dom    Ion_trans_dom    K_chnl_volt-dep_Kv    K_chnl_volt-dep_Kv3    SKP1/BTB/POZ    T1-type_BTB    VG_K_chnl   
Domain families : Pfam (Sanger)BTB_2 (PF02214)    Ion_trans (PF00520)   
Domain families : Pfam (NCBI)pfam02214    pfam00520   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCNC2
DMDM Disease mutations3747
Blocks (Seattle)KCNC2
SuperfamilyQ96PR1
Human Protein AtlasENSG00000166006
Peptide AtlasQ96PR1
HPRD08883
IPIIPI00221367   IPI00162733   IPI00790384   IPI01011210   IPI00171403   IPI01021857   
Protein Interaction databases
DIP (DOE-UCLA)Q96PR1
IntAct (EBI)Q96PR1
FunCoupENSG00000166006
BioGRIDKCNC2
STRING (EMBL)KCNC2
ZODIACKCNC2
Ontologies - Pathways
QuickGOQ96PR1
Ontology : AmiGOvoltage-gated potassium channel activity  voltage-gated potassium channel activity  delayed rectifier potassium channel activity  intracellular  plasma membrane  plasma membrane  integral component of plasma membrane  voltage-gated potassium channel complex  response to light intensity  response to organic cyclic compound  response to amine  membrane  integral component of membrane  basolateral plasma membrane  apical plasma membrane  globus pallidus development  cell junction  axon  dendrite  axolemma  vesicle  response to magnesium ion  neuronal cell body membrane  nitric oxide-cGMP-mediated signaling pathway  presynaptic membrane  terminal bouton  perikaryon  ion channel binding  synapse  postsynaptic membrane  response to ethanol  regulation of insulin secretion  protein homooligomerization  protein heterooligomerization  cellular response to ammonium ion  cellular response to nitric oxide  potassium ion transmembrane transport  potassium ion transmembrane transport  cellular response to toxic substance  positive regulation of potassium ion transmembrane transport  response to nerve growth factor  
Ontology : EGO-EBIvoltage-gated potassium channel activity  voltage-gated potassium channel activity  delayed rectifier potassium channel activity  intracellular  plasma membrane  plasma membrane  integral component of plasma membrane  voltage-gated potassium channel complex  response to light intensity  response to organic cyclic compound  response to amine  membrane  integral component of membrane  basolateral plasma membrane  apical plasma membrane  globus pallidus development  cell junction  axon  dendrite  axolemma  vesicle  response to magnesium ion  neuronal cell body membrane  nitric oxide-cGMP-mediated signaling pathway  presynaptic membrane  terminal bouton  perikaryon  ion channel binding  synapse  postsynaptic membrane  response to ethanol  regulation of insulin secretion  protein homooligomerization  protein heterooligomerization  cellular response to ammonium ion  cellular response to nitric oxide  potassium ion transmembrane transport  potassium ion transmembrane transport  cellular response to toxic substance  positive regulation of potassium ion transmembrane transport  response to nerve growth factor  
NDEx NetworkKCNC2
Atlas of Cancer Signalling NetworkKCNC2
Wikipedia pathwaysKCNC2
Orthology - Evolution
OrthoDB3747
GeneTree (enSembl)ENSG00000166006
Phylogenetic Trees/Animal Genes : TreeFamKCNC2
HOVERGENQ96PR1
HOGENOMQ96PR1
Homologs : HomoloGeneKCNC2
Homology/Alignments : Family Browser (UCSC)KCNC2
Gene fusions - Rearrangements
Fusion: TCGAMARCH9 KCNC2
Fusion: TCGAROR2 KCNC2
Fusion: TCGAATP2B1 KCNC2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNC2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNC2
dbVarKCNC2
ClinVarKCNC2
1000_GenomesKCNC2 
Exome Variant ServerKCNC2
ExAC (Exome Aggregation Consortium)KCNC2 (select the gene name)
Genetic variants : HAPMAP3747
Genomic Variants (DGV)KCNC2 [DGVbeta]
DECIPHERKCNC2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNC2 
Mutations
ICGC Data PortalKCNC2 
TCGA Data PortalKCNC2 
Broad Tumor PortalKCNC2
OASIS PortalKCNC2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNC2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNC2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNC2
DgiDB (Drug Gene Interaction Database)KCNC2
DoCM (Curated mutations)KCNC2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNC2 (select a term)
intoGenKCNC2
Cancer3DKCNC2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176256   
Orphanet
MedgenKCNC2
Genetic Testing Registry KCNC2
NextProtQ96PR1 [Medical]
TSGene3747
GENETestsKCNC2
Target ValidationKCNC2
Huge Navigator KCNC2 [HugePedia]
snp3D : Map Gene to Disease3747
BioCentury BCIQKCNC2
ClinGenKCNC2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3747
Chemical/Pharm GKB GenePA35490
Clinical trialKCNC2
Miscellaneous
canSAR (ICR)KCNC2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNC2
EVEXKCNC2
GoPubMedKCNC2
iHOPKCNC2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:54:03 CEST 2017

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