Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KCNC3 (potassium voltage-gated channel subfamily C member 3)

Identity

Alias (NCBI)KSHIIID
KV3.3
SCA13
HGNC (Hugo) KCNC3
HGNC Alias symbKv3.3
HGNC Previous nameSCA13
HGNC Previous namespinocerebellar ataxia 13
 potassium voltage-gated channel, Shaw-related subfamily, member 3
 potassium channel, voltage gated Shaw related subfamily C, member 3
LocusID (NCBI) 3748
Atlas_Id 64768
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 50311940 and ends at 50329377 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCNC3 (19q13.33) / ASPDH (19q13.33)KCNC3 (19q13.33) / SMG1 (16p12.3)NLGN1 (3q26.31) / KCNC3 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KCNC3   6235
LRG (Locus Reference Genomic)LRG_668
Cards
Entrez_Gene (NCBI)KCNC3    potassium voltage-gated channel subfamily C member 3
AliasesKSHIIID; KV3.3; SCA13
GeneCards (Weizmann)KCNC3
Ensembl hg19 (Hinxton)ENSG00000131398 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131398 [Gene_View]  ENSG00000131398 [Sequence]  chr19:50311940-50329377 [Contig_View]  KCNC3 [Vega]
ICGC DataPortalENSG00000131398
TCGA cBioPortalKCNC3
AceView (NCBI)KCNC3
Genatlas (Paris)KCNC3
SOURCE (Princeton)KCNC3
Genetics Home Reference (NIH)KCNC3
Genomic and cartography
GoldenPath hg38 (UCSC)KCNC3  -     chr19:50311940-50329377 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNC3  -     19q13.33   [Description]    (hg19-Feb_2009)
GoldenPathKCNC3 - 19q13.33 [CytoView hg19]  KCNC3 - 19q13.33 [CytoView hg38]
ImmunoBaseENSG00000131398
Genome Data Viewer NCBIKCNC3 [Mapview hg19]  
OMIM176264   605259   
Gene and transcription
Genbank (Entrez)AB208930 AF055989 AK127492
RefSeq transcript (Entrez)NM_001372305 NM_004977
Consensus coding sequences : CCDS (NCBI)KCNC3
Gene ExpressionKCNC3 [ NCBI-GEO ]   KCNC3 [ EBI - ARRAY_EXPRESS ]   KCNC3 [ SEEK ]   KCNC3 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNC3 [ Firebrowse - Broad ]
GenevisibleExpression of KCNC3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3748
GTEX Portal (Tissue expression)KCNC3
Human Protein AtlasENSG00000131398-KCNC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14003   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14003  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14003
PhosPhoSitePlusQ14003
Domains : Interpro (EBI)BTB/POZ_dom    Ion_trans_dom    K_chnl_volt-dep_Kv    K_chnl_volt-dep_Kv3    K_chnl_volt-dep_Kv3.3    K_chnl_volt-dep_Kv3_ID    SKP1/BTB/POZ_sf    T1-type_BTB    VG_K_chnl    Volt_channel_dom_sf   
Domain families : Pfam (Sanger)BTB_2 (PF02214)    Ion_trans (PF00520)    Potassium_chann (PF11404)   
Domain families : Pfam (NCBI)pfam02214    pfam00520    pfam11404   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCNC3
SuperfamilyQ14003
AlphaFold pdb e-kbQ14003   
Human Protein Atlas [tissue]ENSG00000131398-KCNC3 [tissue]
HPRD08886
Protein Interaction databases
DIP (DOE-UCLA)Q14003
IntAct (EBI)Q14003
BioGRIDKCNC3
STRING (EMBL)KCNC3
ZODIACKCNC3
Ontologies - Pathways
QuickGOQ14003
Ontology : AmiGOvoltage-gated potassium channel activity  voltage-gated potassium channel activity  delayed rectifier potassium channel activity  cytoskeleton  plasma membrane  plasma membrane  cell cortex  voltage-gated potassium channel complex  voltage-gated potassium channel complex  integral component of membrane  axon  dendrite membrane  dendritic spine membrane  neuronal cell body membrane  regulation of ion transmembrane transport  presynaptic membrane  perikaryon  postsynaptic membrane  protein homooligomerization  protein tetramerization  potassium ion transmembrane transport  potassium ion transmembrane transport  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  voltage-gated potassium channel activity  delayed rectifier potassium channel activity  cytoskeleton  plasma membrane  plasma membrane  cell cortex  voltage-gated potassium channel complex  voltage-gated potassium channel complex  integral component of membrane  axon  dendrite membrane  dendritic spine membrane  neuronal cell body membrane  regulation of ion transmembrane transport  presynaptic membrane  perikaryon  postsynaptic membrane  protein homooligomerization  protein tetramerization  potassium ion transmembrane transport  potassium ion transmembrane transport  potassium ion transmembrane transport  
NDEx NetworkKCNC3
Atlas of Cancer Signalling NetworkKCNC3
Wikipedia pathwaysKCNC3
Orthology - Evolution
OrthoDB3748
GeneTree (enSembl)ENSG00000131398
Phylogenetic Trees/Animal Genes : TreeFamKCNC3
Homologs : HomoloGeneKCNC3
Homology/Alignments : Family Browser (UCSC)KCNC3
Gene fusions - Rearrangements
Fusion : QuiverKCNC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNC3
dbVarKCNC3
ClinVarKCNC3
MonarchKCNC3
1000_GenomesKCNC3 
Exome Variant ServerKCNC3
GNOMAD BrowserENSG00000131398
Varsome BrowserKCNC3
ACMGKCNC3 variants
VarityQ14003
Genomic Variants (DGV)KCNC3 [DGVbeta]
DECIPHERKCNC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNC3 
Mutations
ICGC Data PortalKCNC3 
TCGA Data PortalKCNC3 
Broad Tumor PortalKCNC3
OASIS PortalKCNC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNC3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKCNC3
Mutations and Diseases : HGMDKCNC3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKCNC3
DgiDB (Drug Gene Interaction Database)KCNC3
DoCM (Curated mutations)KCNC3
CIViC (Clinical Interpretations of Variants in Cancer)KCNC3
Cancer3DKCNC3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176264    605259   
Orphanet13785   
DisGeNETKCNC3
MedgenKCNC3
Genetic Testing Registry KCNC3
NextProtQ14003 [Medical]
GENETestsKCNC3
Target ValidationKCNC3
Huge Navigator KCNC3 [HugePedia]
ClinGenKCNC3
Clinical trials, drugs, therapy
MyCancerGenomeKCNC3
Protein Interactions : CTDKCNC3
Pharm GKB GenePA30027
PharosQ14003
Clinical trialKCNC3
Miscellaneous
canSAR (ICR)KCNC3
HarmonizomeKCNC3
DataMed IndexKCNC3
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKCNC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:54:17 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.