Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCND2 (potassium voltage-gated channel subfamily D member 2)

Identity

Alias_namespotassium voltage-gated channel
Alias_symbol (synonym)Kv4.2
RK5
KIAA1044
Other aliasKV4.2
HGNC (Hugo) KCND2
LocusID (NCBI) 3751
Atlas_Id 55511
Location 7q31.31  [Link to chromosome band 7q31]
Location_base_pair Starts at 120273668 and ends at 120750333 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
POU6F2 (7p14.1) / KCND2 (7q31.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCND2   6238
Cards
Entrez_Gene (NCBI)KCND2  3751  potassium voltage-gated channel subfamily D member 2
AliasesKV4.2; RK5
GeneCards (Weizmann)KCND2
Ensembl hg19 (Hinxton)ENSG00000184408 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184408 [Gene_View]  chr7:120273668-120750333 [Contig_View]  KCND2 [Vega]
ICGC DataPortalENSG00000184408
TCGA cBioPortalKCND2
AceView (NCBI)KCND2
Genatlas (Paris)KCND2
WikiGenes3751
SOURCE (Princeton)KCND2
Genetics Home Reference (NIH)KCND2
Genomic and cartography
GoldenPath hg38 (UCSC)KCND2  -     chr7:120273668-120750333 +  7q31.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCND2  -     7q31.31   [Description]    (hg19-Feb_2009)
EnsemblKCND2 - 7q31.31 [CytoView hg19]  KCND2 - 7q31.31 [CytoView hg38]
Mapping of homologs : NCBIKCND2 [Mapview hg19]  KCND2 [Mapview hg38]
OMIM605410   
Gene and transcription
Genbank (Entrez)AB028967 AF121104 AJ010969 AK307139 BC110449
RefSeq transcript (Entrez)NM_012281
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCND2
Cluster EST : UnigeneHs.654739 [ NCBI ]
CGAP (NCI)Hs.654739
Alternative Splicing GalleryENSG00000184408
Gene ExpressionKCND2 [ NCBI-GEO ]   KCND2 [ EBI - ARRAY_EXPRESS ]   KCND2 [ SEEK ]   KCND2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCND2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3751
GTEX Portal (Tissue expression)KCND2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZV8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NZV8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NZV8
Splice isoforms : SwissVarQ9NZV8
PhosPhoSitePlusQ9NZV8
Domains : Interpro (EBI)BTB/POZ_dom    Channel_four-helix_dom    Ion_trans_dom    K_chnl_volt-dep_Kv    K_chnl_volt-dep_Kv4    K_chnl_volt-dep_Kv4.2    K_chnl_volt-dep_Kv4_C    Shal-type_N    SKP1/BTB/POZ    T1-type_BTB    VG_K_chnl   
Domain families : Pfam (Sanger)BTB_2 (PF02214)    DUF3399 (PF11879)    Ion_trans (PF00520)    Shal-type (PF11601)   
Domain families : Pfam (NCBI)pfam02214    pfam11879    pfam00520    pfam11601   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCND2
DMDM Disease mutations3751
Blocks (Seattle)KCND2
SuperfamilyQ9NZV8
Human Protein AtlasENSG00000184408
Peptide AtlasQ9NZV8
HPRD09254
IPIIPI00930660   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZV8
IntAct (EBI)Q9NZV8
FunCoupENSG00000184408
BioGRIDKCND2
STRING (EMBL)KCND2
ZODIACKCND2
Ontologies - Pathways
QuickGOQ9NZV8
Ontology : AmiGOaction potential  voltage-gated potassium channel activity  voltage-gated potassium channel activity  voltage-gated potassium channel activity  A-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  protein binding  plasma membrane  integral component of plasma membrane  chemical synaptic transmission  voltage-gated potassium channel complex  neuronal action potential  sensory perception of pain  cell junction  intrinsic component of plasma membrane  neuronal cell body membrane  regulation of ion transmembrane transport  dendritic spine  dendritic spine  perikaryon  plasma membrane raft  postsynaptic membrane  locomotor rhythm  metal ion binding  protein homooligomerization  cardiac conduction  cellular response to hypoxia  potassium ion transmembrane transport  
Ontology : EGO-EBIaction potential  voltage-gated potassium channel activity  voltage-gated potassium channel activity  voltage-gated potassium channel activity  A-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  protein binding  plasma membrane  integral component of plasma membrane  chemical synaptic transmission  voltage-gated potassium channel complex  neuronal action potential  sensory perception of pain  cell junction  intrinsic component of plasma membrane  neuronal cell body membrane  regulation of ion transmembrane transport  dendritic spine  dendritic spine  perikaryon  plasma membrane raft  postsynaptic membrane  locomotor rhythm  metal ion binding  protein homooligomerization  cardiac conduction  cellular response to hypoxia  potassium ion transmembrane transport  
Pathways : KEGGSerotonergic synapse   
NDEx NetworkKCND2
Atlas of Cancer Signalling NetworkKCND2
Wikipedia pathwaysKCND2
Orthology - Evolution
OrthoDB3751
GeneTree (enSembl)ENSG00000184408
Phylogenetic Trees/Animal Genes : TreeFamKCND2
HOVERGENQ9NZV8
HOGENOMQ9NZV8
Homologs : HomoloGeneKCND2
Homology/Alignments : Family Browser (UCSC)KCND2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCND2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCND2
dbVarKCND2
ClinVarKCND2
1000_GenomesKCND2 
Exome Variant ServerKCND2
ExAC (Exome Aggregation Consortium)KCND2 (select the gene name)
Genetic variants : HAPMAP3751
Genomic Variants (DGV)KCND2 [DGVbeta]
DECIPHERKCND2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCND2 
Mutations
ICGC Data PortalKCND2 
TCGA Data PortalKCND2 
Broad Tumor PortalKCND2
OASIS PortalKCND2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCND2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCND2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCND2
DgiDB (Drug Gene Interaction Database)KCND2
DoCM (Curated mutations)KCND2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCND2 (select a term)
intoGenKCND2
Cancer3DKCND2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605410   
Orphanet
MedgenKCND2
Genetic Testing Registry KCND2
NextProtQ9NZV8 [Medical]
TSGene3751
GENETestsKCND2
Target ValidationKCND2
Huge Navigator KCND2 [HugePedia]
snp3D : Map Gene to Disease3751
BioCentury BCIQKCND2
ClinGenKCND2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3751
Chemical/Pharm GKB GenePA30030
Clinical trialKCND2
Miscellaneous
canSAR (ICR)KCND2 (select the gene name)
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCND2
EVEXKCND2
GoPubMedKCND2
iHOPKCND2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:39:12 CEST 2017

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