Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNE5 (potassium voltage-gated channel subfamily E regulatory subunit 5)

Identity

Alias_namesKCNE1L
potassium voltage-gated channel, Isk-related family, member 1-like
potassium channel, voltage gated subfamily E regulatory beta subunit 5
Other alias
HGNC (Hugo) KCNE5
LocusID (NCBI) 23630
Atlas_Id 77664
Location Xq23  [Link to chromosome band Xq23]
Location_base_pair Starts at 109623700 and ends at 109625168 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNE5   6241
LRG (Locus Reference Genomic)LRG_1083
Cards
Entrez_Gene (NCBI)KCNE5  23630  potassium voltage-gated channel subfamily E regulatory subunit 5
AliasesKCNE1L
GeneCards (Weizmann)KCNE5
Ensembl hg19 (Hinxton)ENSG00000176076 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176076 [Gene_View]  chrX:109623700-109625168 [Contig_View]  KCNE5 [Vega]
ICGC DataPortalENSG00000176076
TCGA cBioPortalKCNE5
AceView (NCBI)KCNE5
Genatlas (Paris)KCNE5
WikiGenes23630
SOURCE (Princeton)KCNE5
Genetics Home Reference (NIH)KCNE5
Genomic and cartography
GoldenPath hg38 (UCSC)KCNE5  -     chrX:109623700-109625168 -  Xq23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNE5  -     Xq23   [Description]    (hg19-Feb_2009)
EnsemblKCNE5 - Xq23 [CytoView hg19]  KCNE5 - Xq23 [CytoView hg38]
Mapping of homologs : NCBIKCNE5 [Mapview hg19]  KCNE5 [Mapview hg38]
OMIM300328   
Gene and transcription
Genbank (Entrez)AF086499 AJ012743 AK223306 AK314923 BC035330
RefSeq transcript (Entrez)NM_012282
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNE5
Cluster EST : UnigeneHs.522753 [ NCBI ]
CGAP (NCI)Hs.522753
Alternative Splicing GalleryENSG00000176076
Gene ExpressionKCNE5 [ NCBI-GEO ]   KCNE5 [ EBI - ARRAY_EXPRESS ]   KCNE5 [ SEEK ]   KCNE5 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNE5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23630
GTEX Portal (Tissue expression)KCNE5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJ90   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJ90  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJ90
Splice isoforms : SwissVarQ9UJ90
PhosPhoSitePlusQ9UJ90
Domains : Interpro (EBI)K_chnl_KCNE   
Domain families : Pfam (Sanger)ISK_Channel (PF02060)   
Domain families : Pfam (NCBI)pfam02060   
Conserved Domain (NCBI)KCNE5
DMDM Disease mutations23630
Blocks (Seattle)KCNE5
SuperfamilyQ9UJ90
Human Protein AtlasENSG00000176076
Peptide AtlasQ9UJ90
HPRD02268
IPIIPI00017519   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJ90
IntAct (EBI)Q9UJ90
FunCoupENSG00000176076
BioGRIDKCNE5
STRING (EMBL)KCNE5
ZODIACKCNE5
Ontologies - Pathways
QuickGOQ9UJ90
Ontology : AmiGOvoltage-gated potassium channel activity  protein binding  plasma membrane  regulation of heart contraction  voltage-gated potassium channel complex  potassium channel regulator activity  ion channel binding  cardiac muscle contraction  regulation of membrane repolarization  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of atrial cardiac muscle cell membrane repolarization  potassium ion export  potassium ion transmembrane transport  ventricular cardiac muscle cell action potential  voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization  membrane repolarization during cardiac muscle cell action potential  atrial cardiac muscle cell action potential  regulation of heart rate by cardiac conduction  regulation of potassium ion transmembrane transport  negative regulation of potassium ion transmembrane transport  positive regulation of potassium ion transmembrane transport  regulation of cation channel activity  
Ontology : EGO-EBIvoltage-gated potassium channel activity  protein binding  plasma membrane  regulation of heart contraction  voltage-gated potassium channel complex  potassium channel regulator activity  ion channel binding  cardiac muscle contraction  regulation of membrane repolarization  regulation of ventricular cardiac muscle cell membrane repolarization  regulation of atrial cardiac muscle cell membrane repolarization  potassium ion export  potassium ion transmembrane transport  ventricular cardiac muscle cell action potential  voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization  membrane repolarization during cardiac muscle cell action potential  atrial cardiac muscle cell action potential  regulation of heart rate by cardiac conduction  regulation of potassium ion transmembrane transport  negative regulation of potassium ion transmembrane transport  positive regulation of potassium ion transmembrane transport  regulation of cation channel activity  
NDEx NetworkKCNE5
Atlas of Cancer Signalling NetworkKCNE5
Wikipedia pathwaysKCNE5
Orthology - Evolution
OrthoDB23630
GeneTree (enSembl)ENSG00000176076
Phylogenetic Trees/Animal Genes : TreeFamKCNE5
HOVERGENQ9UJ90
HOGENOMQ9UJ90
Homologs : HomoloGeneKCNE5
Homology/Alignments : Family Browser (UCSC)KCNE5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNE5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNE5
dbVarKCNE5
ClinVarKCNE5
1000_GenomesKCNE5 
Exome Variant ServerKCNE5
ExAC (Exome Aggregation Consortium)KCNE5 (select the gene name)
Genetic variants : HAPMAP23630
Genomic Variants (DGV)KCNE5 [DGVbeta]
DECIPHERKCNE5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNE5 
Mutations
ICGC Data PortalKCNE5 
TCGA Data PortalKCNE5 
Broad Tumor PortalKCNE5
OASIS PortalKCNE5 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDKCNE5
BioMutasearch KCNE5
DgiDB (Drug Gene Interaction Database)KCNE5
DoCM (Curated mutations)KCNE5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNE5 (select a term)
intoGenKCNE5
Cancer3DKCNE5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300328   
Orphanet11738   
MedgenKCNE5
Genetic Testing Registry KCNE5
NextProtQ9UJ90 [Medical]
TSGene23630
GENETestsKCNE5
Huge Navigator KCNE5 [HugePedia]
snp3D : Map Gene to Disease23630
BioCentury BCIQKCNE5
ClinGenKCNE5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23630
Chemical/Pharm GKB GenePA30031
Clinical trialKCNE5
Miscellaneous
canSAR (ICR)KCNE5 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNE5
EVEXKCNE5
GoPubMedKCNE5
iHOPKCNE5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 11:17:32 CEST 2017

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