KCNH6 (potassium voltage-gated channel subfamily H member 6)

2014-06-01  

Identity

HGNC
LOCATION
17q23.3
LOCUSID
ALIAS
ERG-2,ERG2,HERG2,Kv11.2,hERG-2
FUSION GENES

Other Information

Locus ID:

NCBI: 81033
MIM: 608168
HGNC: 18862
Ensembl: ENSG00000173826

Variants:

dbSNP: 81033
ClinVar: 81033
TCGA: ENSG00000173826
COSMIC: KCNH6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173826ENST00000314672J9JID4
ENSG00000173826ENST00000456941Q9H252
ENSG00000173826ENST00000580652Q9H252
ENSG00000173826ENST00000581784Q9H252
ENSG00000173826ENST00000583023Q9H252
ENSG00000173826ENST00000583465J3KSC2

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Potassium ChannelsREACTOMER-HSA-1296071
Voltage gated Potassium channelsREACTOMER-HSA-1296072

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
126349312003HERG K(+) currents in human prolactin-secreting adenoma cells.13
257830512015MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma.9
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5
305900502018From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion.2

Citation

Dessen P

KCNH6 (potassium voltage-gated channel subfamily H member 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53998/kcnh6