Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNH7 (potassium voltage-gated channel subfamily H member 7)

Identity

Alias_namespotassium voltage-gated channel
Alias_symbol (synonym)Kv11.3
HERG3
erg3
Other aliasERG3
HGNC (Hugo) KCNH7
LocusID (NCBI) 90134
Atlas_Id 54005
Location 2q24.2  [Link to chromosome band 2q24]
Location_base_pair Starts at 163227917 and ends at 163695257 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KCNH7 (2q24.2) / GCNT2 (6p24.3)KCNH7 (2q24.2) / ZNF16 (8q24.3)MYT1L (2p25.3) / KCNH7 (2q24.2)
TMEM167A (5q14.2) / KCNH7 (2q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNH7   18863
Cards
Entrez_Gene (NCBI)KCNH7  90134  potassium voltage-gated channel subfamily H member 7
AliasesERG3; HERG3; Kv11.3
GeneCards (Weizmann)KCNH7
Ensembl hg19 (Hinxton)ENSG00000184611 [Gene_View]  chr2:163227917-163695257 [Contig_View]  KCNH7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000184611 [Gene_View]  chr2:163227917-163695257 [Contig_View]  KCNH7 [Vega]
ICGC DataPortalENSG00000184611
TCGA cBioPortalKCNH7
AceView (NCBI)KCNH7
Genatlas (Paris)KCNH7
WikiGenes90134
SOURCE (Princeton)KCNH7
Genetics Home Reference (NIH)KCNH7
Genomic and cartography
GoldenPath hg19 (UCSC)KCNH7  -     chr2:163227917-163695257 -  2q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNH7  -     2q24.2   [Description]    (hg38-Dec_2013)
EnsemblKCNH7 - 2q24.2 [CytoView hg19]  KCNH7 - 2q24.2 [CytoView hg38]
Mapping of homologs : NCBIKCNH7 [Mapview hg19]  KCNH7 [Mapview hg38]
OMIM608169   
Gene and transcription
Genbank (Entrez)AF032897 AK098545 BC035815 DR002425
RefSeq transcript (Entrez)NM_033272 NM_173162
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_041938 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)KCNH7
Cluster EST : UnigeneHs.657413 [ NCBI ]
CGAP (NCI)Hs.657413
Alternative Splicing GalleryENSG00000184611
Gene ExpressionKCNH7 [ NCBI-GEO ]   KCNH7 [ EBI - ARRAY_EXPRESS ]   KCNH7 [ SEEK ]   KCNH7 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNH7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)90134
GTEX Portal (Tissue expression)KCNH7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS40
Splice isoforms : SwissVarQ9NS40
PhosPhoSitePlusQ9NS40
Domaine pattern : Prosite (Expaxy)CNMP_BINDING_3 (PS50042)   
Domains : Interpro (EBI)cNMP-bd-like    cNMP-bd_dom    Ion_trans_dom    K_chnl_volt-dep_EAG/ELK/ERG    K_chnl_volt-dep_ERG    PAC    PAS    RmlC-like_jellyroll   
Domain families : Pfam (Sanger)cNMP_binding (PF00027)    Ion_trans (PF00520)    PAS_9 (PF13426)   
Domain families : Pfam (NCBI)pfam00027    pfam00520    pfam13426   
Domain families : Smart (EMBL)cNMP (SM00100)  PAC (SM00086)  PAS (SM00091)  
Conserved Domain (NCBI)KCNH7
DMDM Disease mutations90134
Blocks (Seattle)KCNH7
SuperfamilyQ9NS40
Human Protein AtlasENSG00000184611
Peptide AtlasQ9NS40
HPRD16295
IPIIPI00299946   IPI00175643   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS40
IntAct (EBI)Q9NS40
FunCoupENSG00000184611
BioGRIDKCNH7
STRING (EMBL)KCNH7
ZODIACKCNH7
Ontologies - Pathways
QuickGOQ9NS40
Ontology : AmiGOvoltage-gated potassium channel activity  plasma membrane  integral component of plasma membrane  regulation of ion transmembrane transport  regulation of membrane potential  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  plasma membrane  integral component of plasma membrane  regulation of ion transmembrane transport  regulation of membrane potential  potassium ion transmembrane transport  
NDEx NetworkKCNH7
Atlas of Cancer Signalling NetworkKCNH7
Wikipedia pathwaysKCNH7
Orthology - Evolution
OrthoDB90134
GeneTree (enSembl)ENSG00000184611
Phylogenetic Trees/Animal Genes : TreeFamKCNH7
HOVERGENQ9NS40
HOGENOMQ9NS40
Homologs : HomoloGeneKCNH7
Homology/Alignments : Family Browser (UCSC)KCNH7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNH7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNH7
dbVarKCNH7
ClinVarKCNH7
1000_GenomesKCNH7 
Exome Variant ServerKCNH7
ExAC (Exome Aggregation Consortium)KCNH7 (select the gene name)
Genetic variants : HAPMAP90134
Genomic Variants (DGV)KCNH7 [DGVbeta]
DECIPHER (Syndromes)2:163227917-163695257  ENSG00000184611
CONAN: Copy Number AnalysisKCNH7 
Mutations
ICGC Data PortalKCNH7 
TCGA Data PortalKCNH7 
Broad Tumor PortalKCNH7
OASIS PortalKCNH7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNH7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNH7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNH7
DgiDB (Drug Gene Interaction Database)KCNH7
DoCM (Curated mutations)KCNH7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNH7 (select a term)
intoGenKCNH7
Cancer3DKCNH7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608169   
Orphanet
MedgenKCNH7
Genetic Testing Registry KCNH7
NextProtQ9NS40 [Medical]
TSGene90134
GENETestsKCNH7
Huge Navigator KCNH7 [HugePedia]
snp3D : Map Gene to Disease90134
BioCentury BCIQKCNH7
ClinGenKCNH7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD90134
Chemical/Pharm GKB GenePA38723
Clinical trialKCNH7
Miscellaneous
canSAR (ICR)KCNH7 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNH7
EVEXKCNH7
GoPubMedKCNH7
iHOPKCNH7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:11:30 CET 2017

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