Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KCNIP2 (potassium voltage-gated channel interacting protein 2)

Identity

Alias_namesKv channel-interacting protein 2
Alias_symbol (synonym)KCHIP2
Other alias
HGNC (Hugo) KCNIP2
LocusID (NCBI) 30819
Atlas_Id 64782
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 101825974 and ends at 101843920 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		C10orf76 (10q24.32) / KCNIP2 (10q24.32)KCNIP2 (10q24.32) / C10orf76 (10q24.32)KCNIP2 (10q24.32) / CBFA2T3 (16q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KCNIP2   15522
Cards
Entrez_Gene (NCBI)KCNIP2  30819  potassium voltage-gated channel interacting protein 2
AliasesKCHIP2
GeneCards (Weizmann)KCNIP2
Ensembl hg19 (Hinxton)ENSG00000120049 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120049 [Gene_View]  chr10:101825974-101843920 [Contig_View]  KCNIP2 [Vega]
ICGC DataPortalENSG00000120049
TCGA cBioPortalKCNIP2
AceView (NCBI)KCNIP2
Genatlas (Paris)KCNIP2
WikiGenes30819
SOURCE (Princeton)KCNIP2
Genetics Home Reference (NIH)KCNIP2
Genomic and cartography
GoldenPath hg38 (UCSC)KCNIP2  -     chr10:101825974-101843920 -  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNIP2  -     10q24.32   [Description]    (hg19-Feb_2009)
EnsemblKCNIP2 - 10q24.32 [CytoView hg19]  KCNIP2 - 10q24.32 [CytoView hg38]
Mapping of homologs : NCBIKCNIP2 [Mapview hg19]  KCNIP2 [Mapview hg38]
OMIM604661   
Gene and transcription
Genbank (Entrez)AB044584 AB044585 AF199598 AF295076 AF295530
RefSeq transcript (Entrez)NM_014591 NM_173191 NM_173192 NM_173193 NM_173194 NM_173195 NM_173197 NM_173342
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNIP2
Cluster EST : UnigeneHs.97044 [ NCBI ]
CGAP (NCI)Hs.97044
Alternative Splicing GalleryENSG00000120049
Gene ExpressionKCNIP2 [ NCBI-GEO ]   KCNIP2 [ EBI - ARRAY_EXPRESS ]   KCNIP2 [ SEEK ]   KCNIP2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNIP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30819
GTEX Portal (Tissue expression)KCNIP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NS61   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NS61  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NS61
Splice isoforms : SwissVarQ9NS61
PhosPhoSitePlusQ9NS61
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    KCNIP2   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)    EF-hand_8 (PF13833)   
Domain families : Pfam (NCBI)pfam13499    pfam13833   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)KCNIP2
DMDM Disease mutations30819
Blocks (Seattle)KCNIP2
SuperfamilyQ9NS61
Human Protein AtlasENSG00000120049
Peptide AtlasQ9NS61
HPRD06880
IPIIPI00173952   IPI00005558   IPI00289162   IPI00306640   IPI00646538   IPI00298990   IPI00008959   IPI00045897   IPI00045898   IPI00902591   IPI00910655   IPI00911000   IPI00651753   IPI00642758   
Protein Interaction databases
DIP (DOE-UCLA)Q9NS61
IntAct (EBI)Q9NS61
FunCoupENSG00000120049
BioGRIDKCNIP2
STRING (EMBL)KCNIP2
ZODIACKCNIP2
Ontologies - Pathways
QuickGOQ9NS61
Ontology : AmiGOA-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  calcium ion binding  detection of calcium ion  protein binding  cytoplasm  plasma membrane  potassium ion transport  muscle contraction  signal transduction  chemical synaptic transmission  regulation of heart contraction  voltage-gated potassium channel complex  voltage-gated potassium channel complex  potassium channel regulator activity  potassium channel complex  ion channel binding  clustering of voltage-gated potassium channels  ER retention sequence binding  protein N-terminus binding  cardiac conduction  potassium ion export  potassium ion transmembrane transport  voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization  membrane repolarization  membrane repolarization during cardiac muscle cell action potential  potassium ion export across plasma membrane  potassium ion export across plasma membrane  regulation of potassium ion transmembrane transport  regulation of cation channel activity  
Ontology : EGO-EBIA-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  A-type (transient outward) potassium channel activity  calcium ion binding  detection of calcium ion  protein binding  cytoplasm  plasma membrane  potassium ion transport  muscle contraction  signal transduction  chemical synaptic transmission  regulation of heart contraction  voltage-gated potassium channel complex  voltage-gated potassium channel complex  potassium channel regulator activity  potassium channel complex  ion channel binding  clustering of voltage-gated potassium channels  ER retention sequence binding  protein N-terminus binding  cardiac conduction  potassium ion export  potassium ion transmembrane transport  voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization  membrane repolarization  membrane repolarization during cardiac muscle cell action potential  potassium ion export across plasma membrane  potassium ion export across plasma membrane  regulation of potassium ion transmembrane transport  regulation of cation channel activity  
NDEx NetworkKCNIP2
Atlas of Cancer Signalling NetworkKCNIP2
Wikipedia pathwaysKCNIP2
Orthology - Evolution
OrthoDB30819
GeneTree (enSembl)ENSG00000120049
Phylogenetic Trees/Animal Genes : TreeFamKCNIP2
HOVERGENQ9NS61
HOGENOMQ9NS61
Homologs : HomoloGeneKCNIP2
Homology/Alignments : Family Browser (UCSC)KCNIP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNIP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNIP2
dbVarKCNIP2
ClinVarKCNIP2
1000_GenomesKCNIP2 
Exome Variant ServerKCNIP2
ExAC (Exome Aggregation Consortium)KCNIP2 (select the gene name)
Genetic variants : HAPMAP30819
Genomic Variants (DGV)KCNIP2 [DGVbeta]
DECIPHERKCNIP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNIP2 
Mutations
ICGC Data PortalKCNIP2 
TCGA Data PortalKCNIP2 
Broad Tumor PortalKCNIP2
OASIS PortalKCNIP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNIP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNIP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNIP2
DgiDB (Drug Gene Interaction Database)KCNIP2
DoCM (Curated mutations)KCNIP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNIP2 (select a term)
intoGenKCNIP2
Cancer3DKCNIP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604661   
Orphanet
MedgenKCNIP2
Genetic Testing Registry KCNIP2
NextProtQ9NS61 [Medical]
TSGene30819
GENETestsKCNIP2
Target ValidationKCNIP2
Huge Navigator KCNIP2 [HugePedia]
snp3D : Map Gene to Disease30819
BioCentury BCIQKCNIP2
ClinGenKCNIP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30819
Chemical/Pharm GKB GenePA30042
Clinical trialKCNIP2
Miscellaneous
canSAR (ICR)KCNIP2 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNIP2
EVEXKCNIP2
GoPubMedKCNIP2
iHOPKCNIP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:11:37 CEST 2017
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