Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNIP3 (potassium voltage-gated channel interacting protein 3)

Identity

Other namesCSEN
DREAM
KCHIP3
HGNC (Hugo) KCNIP3
LocusID (NCBI) 30818
Atlas_Id 45968
Location 2q11.1  [Link to chromosome band 2q11]
Location_base_pair Starts at 96012768 and ends at 96051825 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCL7A (12q24.31) / KCNIP3 (2q11.1)KCNIP3 (2q11.1) / KCNIP3 (2q11.1)KCNIP3 (2q11.1) / PDE2A (11q13.4)
TM4SF4 (3q25.1) / KCNIP3 (2q11.1)BCL7A 12q24.31 / KCNIP3 2q11.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNIP3   15523
Cards
Entrez_Gene (NCBI)KCNIP3  30818  potassium voltage-gated channel interacting protein 3
AliasesCSEN; DREAM; KCHIP3
GeneCards (Weizmann)KCNIP3
Ensembl hg19 (Hinxton)ENSG00000115041 [Gene_View]  chr2:96012768-96051825 [Contig_View]  KCNIP3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000115041 [Gene_View]  chr2:96012768-96051825 [Contig_View]  KCNIP3 [Vega]
ICGC DataPortalENSG00000115041
TCGA cBioPortalKCNIP3
AceView (NCBI)KCNIP3
Genatlas (Paris)KCNIP3
WikiGenes30818
SOURCE (Princeton)KCNIP3
Genomic and cartography
GoldenPath hg19 (UCSC)KCNIP3  -     chr2:96012768-96051825 +  2q11.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNIP3  -     2q11.1   [Description]    (hg38-Dec_2013)
EnsemblKCNIP3 - 2q11.1 [CytoView hg19]  KCNIP3 - 2q11.1 [CytoView hg38]
Mapping of homologs : NCBIKCNIP3 [Mapview hg19]  KCNIP3 [Mapview hg38]
OMIM604662   
Gene and transcription
Genbank (Entrez)AB209076 AF120102 AF199599 AF367022 AJ131730
RefSeq transcript (Entrez)NM_001034914 NM_013434
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929303
Consensus coding sequences : CCDS (NCBI)KCNIP3
Cluster EST : UnigeneHs.437376 [ NCBI ]
CGAP (NCI)Hs.437376
Alternative Splicing GalleryENSG00000115041
Gene ExpressionKCNIP3 [ NCBI-GEO ]   KCNIP3 [ EBI - ARRAY_EXPRESS ]   KCNIP3 [ SEEK ]   KCNIP3 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNIP3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)30818
GTEX Portal (Tissue expression)KCNIP3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2W7 (Uniprot)
NextProtQ9Y2W7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2W7
Splice isoforms : SwissVarQ9Y2W7 (Swissvar)
PhosPhoSitePlusQ9Y2W7
Domaine pattern : Prosite (Expaxy)EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    Recoverin   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)    EF-hand_8 (PF13833)   
Domain families : Pfam (NCBI)pfam13499    pfam13833   
Domain families : Smart (EMBL)EFh (SM00054)  
DMDM Disease mutations30818
Blocks (Seattle)KCNIP3
PDB (SRS)2E6W   
PDB (PDBSum)2E6W   
PDB (IMB)2E6W   
PDB (RSDB)2E6W   
Structural Biology KnowledgeBase2E6W   
SCOP (Structural Classification of Proteins)2E6W   
CATH (Classification of proteins structures)2E6W   
SuperfamilyQ9Y2W7
Human Protein AtlasENSG00000115041
Peptide AtlasQ9Y2W7
HPRD05232
IPIIPI00294320   IPI00045895   IPI00651627   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2W7
IntAct (EBI)Q9Y2W7
FunCoupENSG00000115041
BioGRIDKCNIP3
STRING (EMBL)KCNIP3
ZODIACKCNIP3
Ontologies - Pathways
QuickGOQ9Y2W7
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  DNA binding  transcription corepressor activity  voltage-gated ion channel activity  potassium channel activity  calcium ion binding  protein binding  nucleus  endoplasmic reticulum  Golgi apparatus  cytosol  plasma membrane  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  intracellular protein transport  apoptotic process  signal transduction  voltage-gated potassium channel complex  potassium channel regulator activity  dendrite  protein-DNA complex  axon terminus  ion channel binding  cardiac conduction  potassium ion transmembrane transport  protein localization to plasma membrane  regulation of potassium ion transmembrane transport  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  DNA binding  transcription corepressor activity  voltage-gated ion channel activity  potassium channel activity  calcium ion binding  protein binding  nucleus  endoplasmic reticulum  Golgi apparatus  cytosol  plasma membrane  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  intracellular protein transport  apoptotic process  signal transduction  voltage-gated potassium channel complex  potassium channel regulator activity  dendrite  protein-DNA complex  axon terminus  ion channel binding  cardiac conduction  potassium ion transmembrane transport  protein localization to plasma membrane  regulation of potassium ion transmembrane transport  
Pathways : BIOCARTARepression of Pain Sensation by the Transcriptional Regulator DREAM [Genes]   
NDEx NetworkKCNIP3
Atlas of Cancer Signalling NetworkKCNIP3
Wikipedia pathwaysKCNIP3
Orthology - Evolution
OrthoDB30818
GeneTree (enSembl)ENSG00000115041
Phylogenetic Trees/Animal Genes : TreeFamKCNIP3
Homologs : HomoloGeneKCNIP3
Homology/Alignments : Family Browser (UCSC)KCNIP3
Gene fusions - Rearrangements
Fusion: TCGABCL7A 12q24.31 KCNIP3 2q11.1 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerKCNIP3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNIP3
dbVarKCNIP3
ClinVarKCNIP3
1000_GenomesKCNIP3 
Exome Variant ServerKCNIP3
ExAC (Exome Aggregation Consortium)KCNIP3 (select the gene name)
Genetic variants : HAPMAP30818
Genomic Variants (DGV)KCNIP3 [DGVbeta]
Mutations
ICGC Data PortalKCNIP3 
TCGA Data PortalKCNIP3 
Broad Tumor PortalKCNIP3
OASIS PortalKCNIP3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNIP3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNIP3
DgiDB (Drug Gene Interaction Database)KCNIP3
DoCM (Curated mutations)KCNIP3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNIP3 (select a term)
intoGenKCNIP3
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:96012768-96051825  ENSG00000115041
CONAN: Copy Number AnalysisKCNIP3 
Mutations and Diseases : HGMDKCNIP3
OMIM604662   
MedgenKCNIP3
Genetic Testing Registry KCNIP3
NextProtQ9Y2W7 [Medical]
TSGene30818
GENETestsKCNIP3
Huge Navigator KCNIP3 [HugePedia]
snp3D : Map Gene to Disease30818
BioCentury BCIQKCNIP3
ClinGenKCNIP3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD30818
Chemical/Pharm GKB GenePA26934
Clinical trialKCNIP3
Miscellaneous
canSAR (ICR)KCNIP3 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNIP3
EVEXKCNIP3
GoPubMedKCNIP3
iHOPKCNIP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 19 18:55:57 CEST 2016

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