Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNJ10 (potassium voltage-gated channel subfamily J member 10)

Identity

Alias_namespotassium inwardly-rectifying channel, subfamily J, member 10
Alias_symbol (synonym)Kir4.1
Kir1.2
Other aliasBIRK-10
KCNJ13-PEN
KIR1.2
KIR4.1
SESAME
HGNC (Hugo) KCNJ10
LocusID (NCBI) 3766
Atlas_Id 64786
Location 1q23.2  [Link to chromosome band 1q23]
Location_base_pair Starts at 160037467 and ends at 160070261 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KCNJ10 (1q23.2) / CISD2 (4q24)KCNJ10 (1q23.2) / DCTN1 (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNJ10   6256
Cards
Entrez_Gene (NCBI)KCNJ10  3766  potassium voltage-gated channel subfamily J member 10
AliasesBIRK-10; KCNJ13-PEN; KIR1.2; KIR4.1; 
SESAME
GeneCards (Weizmann)KCNJ10
Ensembl hg19 (Hinxton)ENSG00000177807 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177807 [Gene_View]  chr1:160037467-160070261 [Contig_View]  KCNJ10 [Vega]
ICGC DataPortalENSG00000177807
TCGA cBioPortalKCNJ10
AceView (NCBI)KCNJ10
Genatlas (Paris)KCNJ10
WikiGenes3766
SOURCE (Princeton)KCNJ10
Genetics Home Reference (NIH)KCNJ10
Genomic and cartography
GoldenPath hg38 (UCSC)KCNJ10  -     chr1:160037467-160070261 -  1q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNJ10  -     1q23.2   [Description]    (hg19-Feb_2009)
EnsemblKCNJ10 - 1q23.2 [CytoView hg19]  KCNJ10 - 1q23.2 [CytoView hg38]
Mapping of homologs : NCBIKCNJ10 [Mapview hg19]  KCNJ10 [Mapview hg38]
OMIM274600   600791   602208   612780   
Gene and transcription
Genbank (Entrez)AK312383 BC034036 BC037840 BC131627 BE466069
RefSeq transcript (Entrez)NM_002241
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNJ10
Cluster EST : UnigeneHs.408960 [ NCBI ]
CGAP (NCI)Hs.408960
Alternative Splicing GalleryENSG00000177807
Gene ExpressionKCNJ10 [ NCBI-GEO ]   KCNJ10 [ EBI - ARRAY_EXPRESS ]   KCNJ10 [ SEEK ]   KCNJ10 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNJ10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3766
GTEX Portal (Tissue expression)KCNJ10
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78508
Splice isoforms : SwissVarP78508
PhosPhoSitePlusP78508
Domains : Interpro (EBI)Ig_E-set    K_chnl_inward-rec_Kir    K_chnl_inward-rec_Kir1.2    K_chnl_inward-rec_Kir_cyto   
Domain families : Pfam (Sanger)IRK (PF01007)   
Domain families : Pfam (NCBI)pfam01007   
Conserved Domain (NCBI)KCNJ10
DMDM Disease mutations3766
Blocks (Seattle)KCNJ10
SuperfamilyP78508
Human Protein AtlasENSG00000177807
Peptide AtlasP78508
HPRD03732
IPIIPI00020273   
Protein Interaction databases
DIP (DOE-UCLA)P78508
IntAct (EBI)P78508
FunCoupENSG00000177807
BioGRIDKCNJ10
STRING (EMBL)KCNJ10
ZODIACKCNJ10
Ontologies - Pathways
QuickGOP78508
Ontology : AmiGOinward rectifier potassium channel activity  protein binding  ATP binding  plasma membrane  integral component of plasma membrane  potassium ion transport  visual perception  adult walking behavior  potassium ion import  ATP-activated inward rectifier potassium channel activity  G-protein activated inward rectifier potassium channel activity  basolateral plasma membrane  central nervous system myelination  regulation of ion transmembrane transport  regulation of long-term neuronal synaptic plasticity  glutamate reuptake  potassium ion homeostasis  regulation of resting membrane potential  presynapse  
Ontology : EGO-EBIinward rectifier potassium channel activity  protein binding  ATP binding  plasma membrane  integral component of plasma membrane  potassium ion transport  visual perception  adult walking behavior  potassium ion import  ATP-activated inward rectifier potassium channel activity  G-protein activated inward rectifier potassium channel activity  basolateral plasma membrane  central nervous system myelination  regulation of ion transmembrane transport  regulation of long-term neuronal synaptic plasticity  glutamate reuptake  potassium ion homeostasis  regulation of resting membrane potential  presynapse  
Pathways : KEGGGastric acid secretion   
NDEx NetworkKCNJ10
Atlas of Cancer Signalling NetworkKCNJ10
Wikipedia pathwaysKCNJ10
Orthology - Evolution
OrthoDB3766
GeneTree (enSembl)ENSG00000177807
Phylogenetic Trees/Animal Genes : TreeFamKCNJ10
HOVERGENP78508
HOGENOMP78508
Homologs : HomoloGeneKCNJ10
Homology/Alignments : Family Browser (UCSC)KCNJ10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNJ10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNJ10
dbVarKCNJ10
ClinVarKCNJ10
1000_GenomesKCNJ10 
Exome Variant ServerKCNJ10
ExAC (Exome Aggregation Consortium)KCNJ10 (select the gene name)
Genetic variants : HAPMAP3766
Genomic Variants (DGV)KCNJ10 [DGVbeta]
DECIPHERKCNJ10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNJ10 
Mutations
ICGC Data PortalKCNJ10 
TCGA Data PortalKCNJ10 
Broad Tumor PortalKCNJ10
OASIS PortalKCNJ10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNJ10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNJ10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch KCNJ10
DgiDB (Drug Gene Interaction Database)KCNJ10
DoCM (Curated mutations)KCNJ10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNJ10 (select a term)
intoGenKCNJ10
Cancer3DKCNJ10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM274600    600791    602208    612780   
Orphanet558    18406   
MedgenKCNJ10
Genetic Testing Registry KCNJ10
NextProtP78508 [Medical]
TSGene3766
GENETestsKCNJ10
Target ValidationKCNJ10
Huge Navigator KCNJ10 [HugePedia]
snp3D : Map Gene to Disease3766
BioCentury BCIQKCNJ10
ClinGenKCNJ10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3766
Chemical/Pharm GKB GenePA30043
Clinical trialKCNJ10
Miscellaneous
canSAR (ICR)KCNJ10 (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNJ10
EVEXKCNJ10
GoPubMedKCNJ10
iHOPKCNJ10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:54:07 CEST 2017

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