Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNJ10 (potassium inwardly rectifying channel subfamily J member 10)

Identity

Alias (NCBI)BIRK-10
KCNJ13-PEN
KIR1.2
KIR4.1
SESAME
HGNC (Hugo) KCNJ10
HGNC Alias symbKir4.1
Kir1.2
HGNC Previous namepotassium inwardly-rectifying channel, subfamily J, member 10
LocusID (NCBI) 3766
Atlas_Id 64786
Location 1q23.2  [Link to chromosome band 1q23]
Location_base_pair Starts at 160037467 and ends at 160070160 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCNJ10 (1q23.2) / CISD2 (4q24)KCNJ10 (1q23.2) / DCTN1 (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KCNJ10   6256
Cards
Entrez_Gene (NCBI)KCNJ10    potassium inwardly rectifying channel subfamily J member 10
AliasesBIRK-10; KCNJ13-PEN; KIR1.2; KIR4.1; 
SESAME
GeneCards (Weizmann)KCNJ10
Ensembl hg19 (Hinxton)ENSG00000177807 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177807 [Gene_View]  ENSG00000177807 [Sequence]  chr1:160037467-160070160 [Contig_View]  KCNJ10 [Vega]
ICGC DataPortalENSG00000177807
TCGA cBioPortalKCNJ10
AceView (NCBI)KCNJ10
Genatlas (Paris)KCNJ10
SOURCE (Princeton)KCNJ10
Genetics Home Reference (NIH)KCNJ10
Genomic and cartography
GoldenPath hg38 (UCSC)KCNJ10  -     chr1:160037467-160070160 -  1q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNJ10  -     1q23.2   [Description]    (hg19-Feb_2009)
GoldenPathKCNJ10 - 1q23.2 [CytoView hg19]  KCNJ10 - 1q23.2 [CytoView hg38]
ImmunoBaseENSG00000177807
Genome Data Viewer NCBIKCNJ10 [Mapview hg19]  
OMIM274600   600791   602208   612780   
Gene and transcription
Genbank (Entrez)AK312383 BC034036 BC037840 BC131627 BE466069
RefSeq transcript (Entrez)NM_002241
Consensus coding sequences : CCDS (NCBI)KCNJ10
Gene ExpressionKCNJ10 [ NCBI-GEO ]   KCNJ10 [ EBI - ARRAY_EXPRESS ]   KCNJ10 [ SEEK ]   KCNJ10 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNJ10 [ Firebrowse - Broad ]
GenevisibleExpression of KCNJ10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3766
GTEX Portal (Tissue expression)KCNJ10
Human Protein AtlasENSG00000177807-KCNJ10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP78508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP78508
PhosPhoSitePlusP78508
Domains : Interpro (EBI)Ig_E-set    IRK_C    K_chnl_inward-rec_Kir    K_chnl_inward-rec_Kir1.2    K_chnl_inward-rec_Kir_cyto    Kir_TM   
Domain families : Pfam (Sanger)IRK (PF01007)    IRK_C (PF17655)   
Domain families : Pfam (NCBI)pfam01007    pfam17655   
Conserved Domain (NCBI)KCNJ10
SuperfamilyP78508
AlphaFold pdb e-kbP78508   
Human Protein Atlas [tissue]ENSG00000177807-KCNJ10 [tissue]
HPRD03732
Protein Interaction databases
DIP (DOE-UCLA)P78508
IntAct (EBI)P78508
BioGRIDKCNJ10
STRING (EMBL)KCNJ10
ZODIACKCNJ10
Ontologies - Pathways
QuickGOP78508
Ontology : AmiGOinward rectifier potassium channel activity  protein binding  ATP binding  plasma membrane  plasma membrane  integral component of plasma membrane  potassium ion transport  visual perception  adult walking behavior  ATP-activated inward rectifier potassium channel activity  basolateral plasma membrane  central nervous system myelination  regulation of ion transmembrane transport  cell body  regulation of long-term neuronal synaptic plasticity  glutamate reuptake  potassium ion homeostasis  regulation of resting membrane potential  potassium ion transmembrane transport  astrocyte projection  ciliary base  presynapse  positive regulation of potassium ion transmembrane transport  non-motile cilium assembly  potassium ion import across plasma membrane  
Ontology : EGO-EBIinward rectifier potassium channel activity  protein binding  ATP binding  plasma membrane  plasma membrane  integral component of plasma membrane  potassium ion transport  visual perception  adult walking behavior  ATP-activated inward rectifier potassium channel activity  basolateral plasma membrane  central nervous system myelination  regulation of ion transmembrane transport  cell body  regulation of long-term neuronal synaptic plasticity  glutamate reuptake  potassium ion homeostasis  regulation of resting membrane potential  potassium ion transmembrane transport  astrocyte projection  ciliary base  presynapse  positive regulation of potassium ion transmembrane transport  non-motile cilium assembly  potassium ion import across plasma membrane  
NDEx NetworkKCNJ10
Atlas of Cancer Signalling NetworkKCNJ10
Wikipedia pathwaysKCNJ10
Orthology - Evolution
OrthoDB3766
GeneTree (enSembl)ENSG00000177807
Phylogenetic Trees/Animal Genes : TreeFamKCNJ10
Homologs : HomoloGeneKCNJ10
Homology/Alignments : Family Browser (UCSC)KCNJ10
Gene fusions - Rearrangements
Fusion : QuiverKCNJ10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNJ10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNJ10
dbVarKCNJ10
ClinVarKCNJ10
MonarchKCNJ10
1000_GenomesKCNJ10 
Exome Variant ServerKCNJ10
GNOMAD BrowserENSG00000177807
Varsome BrowserKCNJ10
ACMGKCNJ10 variants
VarityP78508
Genomic Variants (DGV)KCNJ10 [DGVbeta]
DECIPHERKCNJ10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNJ10 
Mutations
ICGC Data PortalKCNJ10 
TCGA Data PortalKCNJ10 
Broad Tumor PortalKCNJ10
OASIS PortalKCNJ10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNJ10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKCNJ10
Mutations and Diseases : HGMDKCNJ10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKCNJ10
DgiDB (Drug Gene Interaction Database)KCNJ10
DoCM (Curated mutations)KCNJ10
CIViC (Clinical Interpretations of Variants in Cancer)KCNJ10
Cancer3DKCNJ10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM274600    600791    602208    612780   
Orphanet558    18406   
DisGeNETKCNJ10
MedgenKCNJ10
Genetic Testing Registry KCNJ10
NextProtP78508 [Medical]
GENETestsKCNJ10
Target ValidationKCNJ10
Huge Navigator KCNJ10 [HugePedia]
ClinGenKCNJ10
Clinical trials, drugs, therapy
MyCancerGenomeKCNJ10
Protein Interactions : CTDKCNJ10
Pharm GKB GenePA30043
PharosP78508
Clinical trialKCNJ10
Miscellaneous
canSAR (ICR)KCNJ10
HarmonizomeKCNJ10
DataMed IndexKCNJ10
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKCNJ10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:54:20 CEST 2021

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