KCNJ14 (potassium inwardly rectifying channel subfamily J member 14)

2014-11-01 Affiliation

Identity

HGNC

KCNJ14

LOCATION

19q13.33

LOCUSID

3770

ALIAS

IRK4,KIR2.4

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3770
MIM: 603953
HGNC: 6260
Ensembl: ENSG00000182324

Variants:

dbSNP: 3770
ClinVar: 3770
TCGA: ENSG00000182324
COSMIC: KCNJ14

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000182324	ENST00000342291	Q9UNX9
ENSG00000182324	ENST00000391884	Q9UNX9

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Cholinergic synapse	KEGG	hsa04725
Oxytocin signaling pathway	KEGG	hsa04921
Oxytocin signaling pathway	KEGG	ko04921
Neuronal System	REACTOME	R-HSA-112316
Potassium Channels	REACTOME	R-HSA-1296071
Inwardly rectifying K+ channels	REACTOME	R-HSA-1296065
Classical Kir channels	REACTOME	R-HSA-1296053
Muscle contraction	REACTOME	R-HSA-397014
Cardiac conduction	REACTOME	R-HSA-5576891
Phase 4 - resting membrane potential	REACTOME	R-HSA-5576886

References

Pubmed ID	Year	Title	Citations
15958527	2005	Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.	28
17347781	2006	Functional expression of inward rectifier potassium channels in cultured human pulmonary smooth muscle cells: evidence for a major role of Kir2.4 subunits.	4
20424473	2010	L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.	0

Citation

Dessen P

KCNJ14 (potassium inwardly rectifying channel subfamily J member 14)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/64787/kcnj14