KCNJ9 (potassium inwardly rectifying channel subfamily J member 9)

2007-02-01  

Identity

HGNC
LOCATION
1q23.2
LOCUSID
ALIAS
GIRK3,KIR3.3

Other Information

Locus ID:

NCBI: 3765
MIM: 600932
HGNC: 6270
Ensembl: ENSG00000162728

Variants:

dbSNP: 3765
ClinVar: 3765
TCGA: ENSG00000162728
COSMIC: KCNJ9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162728ENST00000368088Q92806

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Dopaminergic synapseKEGGko04728
Dopaminergic synapseKEGGhsa04728
Serotonergic synapseKEGGhsa04726
Retrograde endocannabinoid signalingKEGGhsa04723
Retrograde endocannabinoid signalingKEGGko04723
Morphine addictionKEGGhsa05032
Morphine addictionKEGGko05032
Circadian entrainmentKEGGhsa04713
Circadian entrainmentKEGGko04713
Estrogen signaling pathwayKEGGhsa04915
Estrogen signaling pathwayKEGGko04915
Oxytocin signaling pathwayKEGGhsa04921
Oxytocin signaling pathwayKEGGko04921
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellREACTOMER-HSA-112314
GABA receptor activationREACTOMER-HSA-977443
GABA B receptor activationREACTOMER-HSA-977444
Activation of GABAB receptorsREACTOMER-HSA-991365
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunitsREACTOMER-HSA-997272
Potassium ChannelsREACTOMER-HSA-1296071
Inwardly rectifying K+ channelsREACTOMER-HSA-1296065
G protein gated Potassium channelsREACTOMER-HSA-1296059
Activation of G protein gated Potassium channelsREACTOMER-HSA-1296041

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
161091702005Expression of G-protein inwardly rectifying potassium channels (GIRKs) in lung cancer cell lines.16
206103892010Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3.7
199956712010Are GRIK3 (T928G) gene variants in schizophrenia patients different from those in their first-degree relatives?5
113501892001Analysis of linkage disequilibrium between polymorphisms in the KCNJ9 gene with type 2 diabetes mellitus in Pima Indians.2
159111172005No association between common variations in the human alpha 2 subunit gene (ATP1A2) of the sodium-potassium-transporting ATPase and idiopathic generalized epilepsy.1
177277312007Association analysis of chromosome 1 migraine candidate genes.1
216379182011Identification of GIRK2-4 subunits in human esophageal smooth muscle cells.0

Citation

Dessen P

KCNJ9 (potassium inwardly rectifying channel subfamily J member 9)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45699/kcnj9