Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNK5 (potassium channel, two pore domain subfamily K, member 5)

Identity

Other namesK2p5.1
KCNK5b
TASK-2
TASK2
HGNC (Hugo) KCNK5
LocusID (NCBI) 8645
Atlas_Id 51772
Location 6p21.2
Location_base_pair Starts at 39156747 and ends at 39197251 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KCNK5   6280
Cards
Entrez_Gene (NCBI)KCNK5  8645  potassium channel, two pore domain subfamily K, member 5
GeneCards (Weizmann)KCNK5
Ensembl hg19 (Hinxton)ENSG00000164626 [Gene_View]  chr6:39156747-39197251 [Contig_View]  KCNK5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164626 [Gene_View]  chr6:39156747-39197251 [Contig_View]  KCNK5 [Vega]
ICGC DataPortalENSG00000164626
TCGA cBioPortalKCNK5
AceView (NCBI)KCNK5
Genatlas (Paris)KCNK5
WikiGenes8645
SOURCE (Princeton)KCNK5
Genomic and cartography
GoldenPath hg19 (UCSC)KCNK5  -     chr6:39156747-39197251 -  6p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNK5  -     6p21.2   [Description]    (hg38-Dec_2013)
EnsemblKCNK5 - 6p21.2 [CytoView hg19]  KCNK5 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBIKCNK5 [Mapview hg19]  KCNK5 [Mapview hg38]
OMIM603493   
Gene and transcription
Genbank (Entrez)AB743589 AF084830 AK001897 AK314298 BC060793
RefSeq transcript (Entrez)NM_003740
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)KCNK5
Cluster EST : UnigeneHs.444448 [ NCBI ]
CGAP (NCI)Hs.444448
Alternative Splicing : Fast-db (Paris)GSHG0026585
Alternative Splicing GalleryENSG00000164626
Gene ExpressionKCNK5 [ NCBI-GEO ]     KCNK5 [ SEEK ]   KCNK5 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95279 (Uniprot)
NextProtO95279  [Medical]  [Publications]
With graphics : InterProO95279
Splice isoforms : SwissVarO95279 (Swissvar)
Domains : Interpro (EBI)2pore_dom_K_chnl    2pore_dom_K_chnl_dom    2pore_dom_K_chnl_TASK   
Related proteins : CluSTrO95279
Domain families : Pfam (Sanger)Ion_trans_2 (PF07885)   
Domain families : Pfam (NCBI)pfam07885   
DMDM Disease mutations8645
Blocks (Seattle)O95279
Human Protein AtlasENSG00000164626
Peptide AtlasO95279
HPRD04604
IPIIPI00029507   
Protein Interaction databases
DIP (DOE-UCLA)O95279
IntAct (EBI)O95279
FunCoupENSG00000164626
BioGRIDKCNK5
IntegromeDBKCNK5
STRING (EMBL)KCNK5
Ontologies - Pathways
QuickGOO95279
Ontology : AmiGOvoltage-gated ion channel activity  potassium channel activity  integral component of plasma membrane  potassium ion transport  excretion  potassium ion leak channel activity  stabilization of membrane potential  regulation of ion transmembrane transport  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated ion channel activity  potassium channel activity  integral component of plasma membrane  potassium ion transport  excretion  potassium ion leak channel activity  stabilization of membrane potential  regulation of ion transmembrane transport  potassium ion transmembrane transport  
Pathways : KEGGProtein digestion and absorption   
Protein Interaction DatabaseKCNK5
DoCM (Curated mutations)KCNK5
Wikipedia pathwaysKCNK5
Gene fusion - Rearrangements
Gene fusion: TCGAKCNK5 PDE4DIP  KCNK5 KIF6  
Polymorphisms : SNP, variants
NCBI Variation ViewerKCNK5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNK5
dbVarKCNK5
ClinVarKCNK5
1000_GenomesKCNK5 
Exome Variant ServerKCNK5
SNP (GeneSNP Utah)KCNK5
SNP : HGBaseKCNK5
Genetic variants : HAPMAPKCNK5
Genomic Variants (DGV)KCNK5 [DGVbeta]
Mutations
ICGC Data PortalKCNK5 
TCGA Data PortalKCNK5 
Tumor PortalKCNK5
Somatic Mutations in Cancer : COSMICKCNK5 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:39156747-39197251
CONAN: Copy Number AnalysisKCNK5 
Mutations and Diseases : HGMDKCNK5
OMIM603493   
MedgenKCNK5
NextProtO95279 [Medical]
GENETestsKCNK5
Disease Genetic AssociationKCNK5
Huge Navigator KCNK5 [HugePedia]  KCNK5 [HugeCancerGEM]
snp3D : Map Gene to Disease8645
DGIdb (Drug Gene Interaction db)KCNK5
BioCentury BCIQKCNK5
General knowledge
Homologs : HomoloGeneKCNK5
Homology/Alignments : Family Browser (UCSC)KCNK5
Phylogenetic Trees/Animal Genes : TreeFamKCNK5
Chemical/Protein Interactions : CTD8645
Chemical/Pharm GKB GenePA30062
Clinical trialKCNK5
Cancer Resource (Charite)ENSG00000164626
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
CoreMineKCNK5
GoPubMedKCNK5
iHOPKCNK5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jun 27 11:45:08 CEST 2015

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