Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KCNK6 (potassium channel, two pore domain subfamily K, member 6)

Identity

Alias_namespotassium channel, subfamily K, member 6
potassium channel, two pore domain subfamily K, member 6
Alias_symbol (synonym)K2p6.1
TWIK-2
Other aliasKCNK8
TOSS
TWIK2
HGNC (Hugo) KCNK6
LocusID (NCBI) 9424
Atlas_Id 64799
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 38810484 and ends at 38819649 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KCNK6 (19q13.2) / KCNK6 (19q13.2)LMBR1L (12q13.12) / KCNK6 (19q13.2)LOC100507412 (-) / KCNK6 (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNK6   6281
Cards
Entrez_Gene (NCBI)KCNK6  9424  potassium channel, two pore domain subfamily K, member 6
AliasesK2p6.1; KCNK8; TOSS; TWIK-2; 
TWIK2
GeneCards (Weizmann)KCNK6
Ensembl hg19 (Hinxton) [Gene_View]  chr19:38810484-38819649 [Contig_View]  KCNK6 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr19:38810484-38819649 [Contig_View]  KCNK6 [Vega]
TCGA cBioPortalKCNK6
AceView (NCBI)KCNK6
Genatlas (Paris)KCNK6
WikiGenes9424
SOURCE (Princeton)KCNK6
Genetics Home Reference (NIH)KCNK6
Genomic and cartography
GoldenPath hg19 (UCSC)KCNK6  -     chr19:38810484-38819649 +  19q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCNK6  -     19q13.2   [Description]    (hg38-Dec_2013)
EnsemblKCNK6 - 19q13.2 [CytoView hg19]  KCNK6 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBIKCNK6 [Mapview hg19]  KCNK6 [Mapview hg38]
OMIM603939   
Gene and transcription
Genbank (Entrez)AF117708 AF134149 AF281302 AF281303 AK022344
RefSeq transcript (Entrez)NM_004823
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)KCNK6
Cluster EST : UnigeneHs.240395 [ NCBI ]
CGAP (NCI)Hs.240395
Gene ExpressionKCNK6 [ NCBI-GEO ]   KCNK6 [ EBI - ARRAY_EXPRESS ]   KCNK6 [ SEEK ]   KCNK6 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNK6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9424
GTEX Portal (Tissue expression)KCNK6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y257   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y257  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y257
Splice isoforms : SwissVarQ9Y257
PhosPhoSitePlusQ9Y257
Domains : Interpro (EBI)2pore_dom_K_chnl    2pore_dom_K_chnl_dom    2pore_dom_K_chnl_TASK    2pore_dom_K_chnl_TWIK    2pore_dom_K_chnl_TWIK2   
Domain families : Pfam (Sanger)Ion_trans_2 (PF07885)   
Domain families : Pfam (NCBI)pfam07885   
Conserved Domain (NCBI)KCNK6
DMDM Disease mutations9424
Blocks (Seattle)KCNK6
SuperfamilyQ9Y257
Peptide AtlasQ9Y257
HPRD06803
IPIIPI00031756   IPI00216922   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y257
IntAct (EBI)Q9Y257
BioGRIDKCNK6
STRING (EMBL)KCNK6
ZODIACKCNK6
Ontologies - Pathways
QuickGOQ9Y257
Ontology : AmiGOnegative regulation of systemic arterial blood pressure  inward rectifier potassium channel activity  plasma membrane  integral component of plasma membrane  potassium ion transport  synaptic transmission  voltage-gated potassium channel complex  potassium ion leak channel activity  stabilization of membrane potential  regulation of ion transmembrane transport  regulation of resting membrane potential  potassium ion transmembrane transport  
Ontology : EGO-EBInegative regulation of systemic arterial blood pressure  inward rectifier potassium channel activity  plasma membrane  integral component of plasma membrane  potassium ion transport  synaptic transmission  voltage-gated potassium channel complex  potassium ion leak channel activity  stabilization of membrane potential  regulation of ion transmembrane transport  regulation of resting membrane potential  potassium ion transmembrane transport  
NDEx NetworkKCNK6
Atlas of Cancer Signalling NetworkKCNK6
Wikipedia pathwaysKCNK6
Orthology - Evolution
OrthoDB9424
Phylogenetic Trees/Animal Genes : TreeFamKCNK6
HOVERGENQ9Y257
HOGENOMQ9Y257
Homologs : HomoloGeneKCNK6
Homology/Alignments : Family Browser (UCSC)KCNK6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNK6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNK6
dbVarKCNK6
ClinVarKCNK6
1000_GenomesKCNK6 
Exome Variant ServerKCNK6
ExAC (Exome Aggregation Consortium)KCNK6 (select the gene name)
Genetic variants : HAPMAP9424
Genomic Variants (DGV)KCNK6 [DGVbeta]
DECIPHER (Syndromes)19:38810484-38819649  
CONAN: Copy Number AnalysisKCNK6 
Mutations
ICGC Data PortalKCNK6 
TCGA Data PortalKCNK6 
Broad Tumor PortalKCNK6
OASIS PortalKCNK6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNK6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNK6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNK6
DgiDB (Drug Gene Interaction Database)KCNK6
DoCM (Curated mutations)KCNK6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNK6 (select a term)
intoGenKCNK6
Cancer3DKCNK6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603939   
Orphanet
MedgenKCNK6
Genetic Testing Registry KCNK6
NextProtQ9Y257 [Medical]
TSGene9424
GENETestsKCNK6
Huge Navigator KCNK6 [HugePedia]
snp3D : Map Gene to Disease9424
BioCentury BCIQKCNK6
ClinGenKCNK6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9424
Chemical/Pharm GKB GenePA30063
Clinical trialKCNK6
Miscellaneous
canSAR (ICR)KCNK6 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNK6
EVEXKCNK6
GoPubMedKCNK6
iHOPKCNK6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:09:29 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.