Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KCNK9 (potassium two pore domain channel subfamily K member 9)

Identity

Alias (NCBI)K2p9.1
KT3.2
TASK-3
TASK3
HGNC (Hugo) KCNK9
HGNC Alias symbK2p9.1
TASK3
TASK-3
HGNC Previous namepotassium channel, subfamily K, member 9
 potassium channel, two pore domain subfamily K, member 9
LocusID (NCBI) 51305
Atlas_Id 43764
Location 8q24.3  [Link to chromosome band 8q24]
Location_base_pair Starts at 139617121 and ends at 139703123 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
NRDC (1p32.3) / KCNK9 (8q24.3)TRAPPC9 (8q24.3) / KCNK9 (8q24.3)USP2 (11q23.3) / KCNK9 (8q24.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Lung: Translocations in Squamous Cell Carcinoma
t(1;8)(p32;q24) NRD1/KCNK9

External links

Nomenclature
HGNC (Hugo)KCNK9   6283
LRG (Locus Reference Genomic)LRG_1042
Cards
Entrez_Gene (NCBI)KCNK9    potassium two pore domain channel subfamily K member 9
AliasesK2p9.1; KT3.2; TASK-3; TASK3
GeneCards (Weizmann)KCNK9
Ensembl hg19 (Hinxton)ENSG00000169427 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169427 [Gene_View]  ENSG00000169427 [Sequence]  chr8:139617121-139703123 [Contig_View]  KCNK9 [Vega]
ICGC DataPortalENSG00000169427
TCGA cBioPortalKCNK9
AceView (NCBI)KCNK9
Genatlas (Paris)KCNK9
SOURCE (Princeton)KCNK9
Genetics Home Reference (NIH)KCNK9
Genomic and cartography
GoldenPath hg38 (UCSC)KCNK9  -     chr8:139617121-139703123 -  8q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNK9  -     8q24.3   [Description]    (hg19-Feb_2009)
GoldenPathKCNK9 - 8q24.3 [CytoView hg19]  KCNK9 - 8q24.3 [CytoView hg38]
ImmunoBaseENSG00000169427
genome Data Viewer NCBIKCNK9 [Mapview hg19]  
OMIM605874   612292   
Gene and transcription
Genbank (Entrez)AF212829 AF248241 AF257080 AF279809 AK090707
RefSeq transcript (Entrez)NM_001282534
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNK9
Alternative Splicing GalleryENSG00000169427
Gene ExpressionKCNK9 [ NCBI-GEO ]   KCNK9 [ EBI - ARRAY_EXPRESS ]   KCNK9 [ SEEK ]   KCNK9 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNK9 [ Firebrowse - Broad ]
GenevisibleExpression of KCNK9 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51305
GTEX Portal (Tissue expression)KCNK9
Human Protein AtlasENSG00000169427-KCNK9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPC2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPC2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPC2
Splice isoforms : SwissVarQ9NPC2
PhosPhoSitePlusQ9NPC2
Domains : Interpro (EBI)2pore_dom_K_chnl    2pore_dom_K_chnl_TASK    K_chnl_dom    KCNK9   
Domain families : Pfam (Sanger)Ion_trans_2 (PF07885)   
Domain families : Pfam (NCBI)pfam07885   
Conserved Domain (NCBI)KCNK9
Blocks (Seattle)KCNK9
PDB (RSDB)3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
PDB Europe3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
PDB (PDBSum)3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
PDB (IMB)3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
Structural Biology KnowledgeBase3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
SCOP (Structural Classification of Proteins)3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
CATH (Classification of proteins structures)3P1N    3P1O    3P1P    3P1Q    3P1R    3P1S    3SMK    3SML    3SMM    3SMN    3SMO    3SP5    3SPR    3UX0    4FR3    6GHP   
SuperfamilyQ9NPC2
Human Protein Atlas [tissue]ENSG00000169427-KCNK9 [tissue]
Peptide AtlasQ9NPC2
HPRD16167
IPIIPI00014792   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPC2
IntAct (EBI)Q9NPC2
BioGRIDKCNK9
STRING (EMBL)KCNK9
ZODIACKCNK9
Ontologies - Pathways
QuickGOQ9NPC2
Ontology : AmiGOvoltage-gated potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  integral component of plasma membrane  potassium ion transport  synaptic vesicle  potassium ion leak channel activity  stabilization of membrane potential  potassium ion transmembrane transport  potassium ion import across plasma membrane  
Ontology : EGO-EBIvoltage-gated potassium channel activity  potassium channel activity  plasma membrane  plasma membrane  integral component of plasma membrane  potassium ion transport  synaptic vesicle  potassium ion leak channel activity  stabilization of membrane potential  potassium ion transmembrane transport  potassium ion import across plasma membrane  
NDEx NetworkKCNK9
Atlas of Cancer Signalling NetworkKCNK9
Wikipedia pathwaysKCNK9
Orthology - Evolution
OrthoDB51305
GeneTree (enSembl)ENSG00000169427
Phylogenetic Trees/Animal Genes : TreeFamKCNK9
HOGENOMQ9NPC2
Homologs : HomoloGeneKCNK9
Homology/Alignments : Family Browser (UCSC)KCNK9
Gene fusions - Rearrangements
Fusion : MitelmanNRD1/KCNK9 [1p32.3/8q24.3]  
Fusion : QuiverKCNK9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNK9 [hg38]
dbVarKCNK9
ClinVarKCNK9
MonarchKCNK9
1000_GenomesKCNK9 
Exome Variant ServerKCNK9
GNOMAD BrowserENSG00000169427
Varsome BrowserKCNK9
Genomic Variants (DGV)KCNK9 [DGVbeta]
DECIPHERKCNK9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNK9 
Mutations
ICGC Data PortalKCNK9 
TCGA Data PortalKCNK9 
Broad Tumor PortalKCNK9
OASIS PortalKCNK9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNK9  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKCNK9
Mutations and Diseases : HGMDKCNK9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNK9
DgiDB (Drug Gene Interaction Database)KCNK9
DoCM (Curated mutations)KCNK9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNK9 (select a term)
intoGenKCNK9
Cancer3DKCNK9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605874    612292   
Orphanet17620   
DisGeNETKCNK9
MedgenKCNK9
Genetic Testing Registry KCNK9
NextProtQ9NPC2 [Medical]
GENETestsKCNK9
Target ValidationKCNK9
Huge Navigator KCNK9 [HugePedia]
ClinGenKCNK9 (curated)
Clinical trials, drugs, therapy
MyCancerGenomeKCNK9
Protein Interactions : CTD
Pharm GKB GenePA30065
Pharm GKB PathwaysPA162355621   
PharosQ9NPC2
Clinical trialKCNK9
Miscellaneous
canSAR (ICR)KCNK9 (select the gene name)
HarmonizomeKCNK9
DataMed IndexKCNK9
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKCNK9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:21:06 CET 2021
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