Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KCNMB3 (potassium calcium-activated channel subfamily M regulatory beta subunit 3)

Identity

Alias_namesKCNMB2
KCNMBL
potassium large conductance calcium-activated channel, subfamily M beta member 3
potassium channel subfamily M regulatory beta subunit 3
Other aliasBKBETA3
HBETA3
K(VCA)BETA-3
SLO-BETA-3
SLOBETA3
HGNC (Hugo) KCNMB3
LocusID (NCBI) 27094
Atlas_Id 54396
Location 3q26.32  [Link to chromosome band 3q26]
Location_base_pair Starts at 179239749 and ends at 179267050 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PIK3CA (3q26.32) / KCNMB3 (3q26.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNMB3   6287
Cards
Entrez_Gene (NCBI)KCNMB3  27094  potassium calcium-activated channel subfamily M regulatory beta subunit 3
AliasesBKBETA3; HBETA3; K(VCA)BETA-3; KCNMB2; 
KCNMBL; SLO-BETA-3; SLOBETA3
GeneCards (Weizmann)KCNMB3
Ensembl hg19 (Hinxton)ENSG00000171121 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171121 [Gene_View]  chr3:179239749-179267050 [Contig_View]  KCNMB3 [Vega]
ICGC DataPortalENSG00000171121
TCGA cBioPortalKCNMB3
AceView (NCBI)KCNMB3
Genatlas (Paris)KCNMB3
WikiGenes27094
SOURCE (Princeton)KCNMB3
Genetics Home Reference (NIH)KCNMB3
Genomic and cartography
GoldenPath hg38 (UCSC)KCNMB3  -     chr3:179239749-179267050 -  3q26.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNMB3  -     3q26.32   [Description]    (hg19-Feb_2009)
EnsemblKCNMB3 - 3q26.32 [CytoView hg19]  KCNMB3 - 3q26.32 [CytoView hg38]
Mapping of homologs : NCBIKCNMB3 [Mapview hg19]  KCNMB3 [Mapview hg38]
OMIM605222   
Gene and transcription
Genbank (Entrez)AF139471 AF160968 AF170916 AF214561 AI990131
RefSeq transcript (Entrez)NM_001163677 NM_014407 NM_171828 NM_171829 NM_171830
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNMB3
Cluster EST : UnigeneHs.591285 [ NCBI ]
CGAP (NCI)Hs.591285
Alternative Splicing GalleryENSG00000171121
Gene ExpressionKCNMB3 [ NCBI-GEO ]   KCNMB3 [ EBI - ARRAY_EXPRESS ]   KCNMB3 [ SEEK ]   KCNMB3 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNMB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27094
GTEX Portal (Tissue expression)KCNMB3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NPA1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NPA1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NPA1
Splice isoforms : SwissVarQ9NPA1
PhosPhoSitePlusQ9NPA1
Domains : Interpro (EBI)K_chnl_Ca-activ_BK_bsu   
Domain families : Pfam (Sanger)CaKB (PF03185)   
Domain families : Pfam (NCBI)pfam03185   
Conserved Domain (NCBI)KCNMB3
DMDM Disease mutations27094
Blocks (Seattle)KCNMB3
SuperfamilyQ9NPA1
Human Protein AtlasENSG00000171121
Peptide AtlasQ9NPA1
HPRD05563
IPIIPI00299315   IPI00299880   IPI00296154   IPI00249414   IPI00922327   
Protein Interaction databases
DIP (DOE-UCLA)Q9NPA1
IntAct (EBI)Q9NPA1
FunCoupENSG00000171121
BioGRIDKCNMB3
STRING (EMBL)KCNMB3
ZODIACKCNMB3
Ontologies - Pathways
QuickGOQ9NPA1
Ontology : AmiGOaction potential  detection of calcium ion  plasma membrane  integral component of plasma membrane  potassium ion transport  chemical synaptic transmission  voltage-gated potassium channel complex  calcium-activated potassium channel activity  potassium channel regulator activity  potassium channel regulator activity  neuronal action potential  regulation of molecular function  potassium ion transmembrane transport  
Ontology : EGO-EBIaction potential  detection of calcium ion  plasma membrane  integral component of plasma membrane  potassium ion transport  chemical synaptic transmission  voltage-gated potassium channel complex  calcium-activated potassium channel activity  potassium channel regulator activity  potassium channel regulator activity  neuronal action potential  regulation of molecular function  potassium ion transmembrane transport  
Pathways : KEGGVascular smooth muscle contraction    Insulin secretion   
NDEx NetworkKCNMB3
Atlas of Cancer Signalling NetworkKCNMB3
Wikipedia pathwaysKCNMB3
Orthology - Evolution
OrthoDB27094
GeneTree (enSembl)ENSG00000171121
Phylogenetic Trees/Animal Genes : TreeFamKCNMB3
HOVERGENQ9NPA1
HOGENOMQ9NPA1
Homologs : HomoloGeneKCNMB3
Homology/Alignments : Family Browser (UCSC)KCNMB3
Gene fusions - Rearrangements
Fusion : MitelmanPIK3CA/KCNMB3 [3q26.32/3q26.32]  [inv(3)(q26q26)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNMB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNMB3
dbVarKCNMB3
ClinVarKCNMB3
1000_GenomesKCNMB3 
Exome Variant ServerKCNMB3
ExAC (Exome Aggregation Consortium)KCNMB3 (select the gene name)
Genetic variants : HAPMAP27094
Genomic Variants (DGV)KCNMB3 [DGVbeta]
DECIPHERKCNMB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNMB3 
Mutations
ICGC Data PortalKCNMB3 
TCGA Data PortalKCNMB3 
Broad Tumor PortalKCNMB3
OASIS PortalKCNMB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNMB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNMB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNMB3
DgiDB (Drug Gene Interaction Database)KCNMB3
DoCM (Curated mutations)KCNMB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNMB3 (select a term)
intoGenKCNMB3
Cancer3DKCNMB3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605222   
Orphanet
MedgenKCNMB3
Genetic Testing Registry KCNMB3
NextProtQ9NPA1 [Medical]
TSGene27094
GENETestsKCNMB3
Target ValidationKCNMB3
Huge Navigator KCNMB3 [HugePedia]
snp3D : Map Gene to Disease27094
BioCentury BCIQKCNMB3
ClinGenKCNMB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27094
Chemical/Pharm GKB GenePA30067
Clinical trialKCNMB3
Miscellaneous
canSAR (ICR)KCNMB3 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNMB3
EVEXKCNMB3
GoPubMedKCNMB3
iHOPKCNMB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:14:11 CEST 2017

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