KCNS3 (potassium voltage-gated channel modifier subfamily S member 3)

2014-08-01  

Identity

HGNC
LOCATION
2p24.2
LOCUSID
ALIAS
KV9.3

Other Information

Locus ID:

NCBI: 3790
MIM: 603888
HGNC: 6302
Ensembl: ENSG00000170745

Variants:

dbSNP: 3790
ClinVar: 3790
TCGA: ENSG00000170745
COSMIC: KCNS3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170745ENST00000304101Q9BQ31
ENSG00000170745ENST00000403915Q9BQ31
ENSG00000170745ENST00000419802C9J187

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Potassium ChannelsREACTOMER-HSA-1296071
Voltage gated Potassium channelsREACTOMER-HSA-1296072
MetabolismREACTOMER-HSA-1430728
Integration of energy metabolismREACTOMER-HSA-163685
Regulation of insulin secretionREACTOMER-HSA-422356
Glucagon-like Peptide-1 (GLP1) regulates insulin secretionREACTOMER-HSA-381676

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208761972010Stromatoxin-sensitive, heteromultimeric Kv2.1/Kv9.3 channels contribute to myogenic control of cerebral arterial diameter.28
158271172005Fluorescence measurements reveal stoichiometry of K+ channels formed by modulatory and delayed rectifier alpha-subunits.25
241702942014Lower gene expression for KCNS3 potassium channel subunit in parvalbumin-containing neurons in the prefrontal cortex in schizophrenia.25
186769882008A high-density association screen of 155 ion transport genes for involvement with common migraine.22
224223952012Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.12
157143332005Single-nucleotide polymorphisms of the KCNS3 gene are significantly associated with airway hyperresponsiveness.6
157143332005Single-nucleotide polymorphisms of the KCNS3 gene are significantly associated with airway hyperresponsiveness.6
229437052012Expression of an electrically silent voltage-gated potassium channel in the human placenta.4

Citation

Dessen P

KCNS3 (potassium voltage-gated channel modifier subfamily S member 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54398/kcns3