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KCNT2 (potassium sodium-activated channel subfamily T member 2)

Identity

Alias_namespotassium channel, subfamily T, member 2
potassium channel, sodium activated subfamily T, member 2
Alias_symbol (synonym)KCa4.2
SLICK
SLO2.1
Other alias
HGNC (Hugo) KCNT2
LocusID (NCBI) 343450
Atlas_Id 64813
Location 1q31.3  [Link to chromosome band 1q31]
Location_base_pair Starts at 196225781 and ends at 196608576 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KCNT2 (1q31.3) / KCNT2 (1q31.3)PNPO (17q21.32) / KCNT2 (1q31.3)SKI (1p36.33) / KCNT2 (1q31.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCNT2   18866
Cards
Entrez_Gene (NCBI)KCNT2  343450  potassium sodium-activated channel subfamily T member 2
AliasesKCa4.2; SLICK; SLO2.1
GeneCards (Weizmann)KCNT2
Ensembl hg19 (Hinxton)ENSG00000162687 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162687 [Gene_View]  chr1:196225781-196608576 [Contig_View]  KCNT2 [Vega]
ICGC DataPortalENSG00000162687
TCGA cBioPortalKCNT2
AceView (NCBI)KCNT2
Genatlas (Paris)KCNT2
WikiGenes343450
SOURCE (Princeton)KCNT2
Genetics Home Reference (NIH)KCNT2
Genomic and cartography
GoldenPath hg38 (UCSC)KCNT2  -     chr1:196225781-196608576 -  1q31.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCNT2  -     1q31.3   [Description]    (hg19-Feb_2009)
EnsemblKCNT2 - 1q31.3 [CytoView hg19]  KCNT2 - 1q31.3 [CytoView hg38]
Mapping of homologs : NCBIKCNT2 [Mapview hg19]  KCNT2 [Mapview hg38]
OMIM610044   
Gene and transcription
Genbank (Entrez)AK127807 AK131498 AK309729 AY359444 BC103947
RefSeq transcript (Entrez)NM_001287819 NM_001287820 NM_198503
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCNT2
Cluster EST : UnigeneHs.657046 [ NCBI ]
CGAP (NCI)Hs.657046
Alternative Splicing GalleryENSG00000162687
Gene ExpressionKCNT2 [ NCBI-GEO ]   KCNT2 [ EBI - ARRAY_EXPRESS ]   KCNT2 [ SEEK ]   KCNT2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCNT2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)343450
GTEX Portal (Tissue expression)KCNT2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UVM3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UVM3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UVM3
Splice isoforms : SwissVarQ6UVM3
PhosPhoSitePlusQ6UVM3
Domains : Interpro (EBI)K_chnl_BK_asu    K_chnl_dom    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)BK_channel_a (PF03493)    Ion_trans_2 (PF07885)   
Domain families : Pfam (NCBI)pfam03493    pfam07885   
Conserved Domain (NCBI)KCNT2
DMDM Disease mutations343450
Blocks (Seattle)KCNT2
SuperfamilyQ6UVM3
Human Protein AtlasENSG00000162687
Peptide AtlasQ6UVM3
HPRD11584
IPIIPI00398421   IPI00645277   IPI00876957   IPI01010438   IPI01011736   IPI00843803   
Protein Interaction databases
DIP (DOE-UCLA)Q6UVM3
IntAct (EBI)Q6UVM3
FunCoupENSG00000162687
BioGRIDKCNT2
STRING (EMBL)KCNT2
ZODIACKCNT2
Ontologies - Pathways
QuickGOQ6UVM3
Ontology : AmiGOvoltage-gated potassium channel activity  ATP binding  voltage-gated potassium channel complex  calcium-activated potassium channel activity  potassium ion transmembrane transport  
Ontology : EGO-EBIvoltage-gated potassium channel activity  ATP binding  voltage-gated potassium channel complex  calcium-activated potassium channel activity  potassium ion transmembrane transport  
NDEx NetworkKCNT2
Atlas of Cancer Signalling NetworkKCNT2
Wikipedia pathwaysKCNT2
Orthology - Evolution
OrthoDB343450
GeneTree (enSembl)ENSG00000162687
Phylogenetic Trees/Animal Genes : TreeFamKCNT2
HOVERGENQ6UVM3
HOGENOMQ6UVM3
Homologs : HomoloGeneKCNT2
Homology/Alignments : Family Browser (UCSC)KCNT2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCNT2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCNT2
dbVarKCNT2
ClinVarKCNT2
1000_GenomesKCNT2 
Exome Variant ServerKCNT2
ExAC (Exome Aggregation Consortium)KCNT2 (select the gene name)
Genetic variants : HAPMAP343450
Genomic Variants (DGV)KCNT2 [DGVbeta]
DECIPHERKCNT2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCNT2 
Mutations
ICGC Data PortalKCNT2 
TCGA Data PortalKCNT2 
Broad Tumor PortalKCNT2
OASIS PortalKCNT2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCNT2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCNT2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCNT2
DgiDB (Drug Gene Interaction Database)KCNT2
DoCM (Curated mutations)KCNT2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCNT2 (select a term)
intoGenKCNT2
Cancer3DKCNT2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610044   
Orphanet
MedgenKCNT2
Genetic Testing Registry KCNT2
NextProtQ6UVM3 [Medical]
TSGene343450
GENETestsKCNT2
Target ValidationKCNT2
Huge Navigator KCNT2 [HugePedia]
snp3D : Map Gene to Disease343450
BioCentury BCIQKCNT2
ClinGenKCNT2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD343450
Chemical/Pharm GKB GenePA38726
Clinical trialKCNT2
Miscellaneous
canSAR (ICR)KCNT2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCNT2
EVEXKCNT2
GoPubMedKCNT2
iHOPKCNT2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:54:14 CEST 2017

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