KCTD11 (potassium channel tetramerization domain containing 11)

2003-05-01  

Identity

HGNC
KCTD11
LOCATION
17p13.1
LOCUSID
147040
ALIAS
C17orf36,KCASH1,REN,REN/KCTD11

Other Information

Locus ID:

NCBI: 147040
MIM: 609848
HGNC: 21302
Ensembl: ENSG00000213859

Variants:

dbSNP: 147040
ClinVar: 147040
TCGA: ENSG00000213859
COSMIC: KCTD11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213859ENST00000333751A0A2U3TZI5
ENSG00000213859ENST00000576980Q693B1
ENSG00000213859ENST00000576980A0A158RFT7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
152496782004REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma.51
205911932010The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors.11
250456672014KCTD11 tumor suppressor gene expression is reduced in prostate adenocarcinoma.6

Citation

Dessen P

KCTD11 (potassium channel tetramerization domain containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41053/kctd11