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KCTD14 (potassium channel tetramerization domain containing 14)

Identity

Alias_namespotassium channel tetramerisation domain containing 14
Alias_symbol (synonym)MGC2376
Other alias-
HGNC (Hugo) KCTD14
LocusID (NCBI) 65987
Atlas_Id 54400
Location 11q14.1  [Link to chromosome band 11q14]
Location_base_pair Starts at 78015715 and ends at 78046191 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
INTS4 (11q14.1) / KCTD14 (11q14.1)KCNIP1 (5q35.1) / KCTD14 (11q14.1)PAK1 (11q13.5) / KCTD14 (11q14.1)
PARG (10q11.23) / KCTD14 (11q14.1)THRSP (11q14.1) / KCTD14 (11q14.1)INTS4 11q14.1 / KCTD14 11q14.1
PAK1 11q13.5 / KCTD14 11q14.1THRSP 11q14.1 / KCTD14 11q14.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Squamous Cell Carcinoma


External links

Nomenclature
HGNC (Hugo)KCTD14   23295
Cards
Entrez_Gene (NCBI)KCTD14  65987  potassium channel tetramerization domain containing 14
Aliases
GeneCards (Weizmann)KCTD14
Ensembl hg19 (Hinxton)ENSG00000151364 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151364 [Gene_View]  chr11:78015715-78046191 [Contig_View]  KCTD14 [Vega]
ICGC DataPortalENSG00000151364
TCGA cBioPortalKCTD14
AceView (NCBI)KCTD14
Genatlas (Paris)KCTD14
WikiGenes65987
SOURCE (Princeton)KCTD14
Genetics Home Reference (NIH)KCTD14
Genomic and cartography
GoldenPath hg38 (UCSC)KCTD14  -     chr11:78015715-78046191 -  11q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCTD14  -     11q14.1   [Description]    (hg19-Feb_2009)
EnsemblKCTD14 - 11q14.1 [CytoView hg19]  KCTD14 - 11q14.1 [CytoView hg38]
Mapping of homologs : NCBIKCTD14 [Mapview hg19]  KCTD14 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK313892 BC001062 BC001929 BU631809 CB993622
RefSeq transcript (Entrez)NM_001282406 NM_023930
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCTD14
Cluster EST : UnigeneHs.709780 [ NCBI ]
CGAP (NCI)Hs.709780
Alternative Splicing GalleryENSG00000151364
Gene ExpressionKCTD14 [ NCBI-GEO ]   KCTD14 [ EBI - ARRAY_EXPRESS ]   KCTD14 [ SEEK ]   KCTD14 [ MEM ]
Gene Expression Viewer (FireBrowse)KCTD14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65987
GTEX Portal (Tissue expression)KCTD14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQ13   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQ13  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQ13
Splice isoforms : SwissVarQ9BQ13
PhosPhoSitePlusQ9BQ13
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    T1-type_BTB   
Domain families : Pfam (Sanger)BTB_2 (PF02214)   
Domain families : Pfam (NCBI)pfam02214   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCTD14
DMDM Disease mutations65987
Blocks (Seattle)KCTD14
SuperfamilyQ9BQ13
Human Protein AtlasENSG00000151364
Peptide AtlasQ9BQ13
HPRD13764
IPIIPI00181836   IPI00985441   
Protein Interaction databases
DIP (DOE-UCLA)Q9BQ13
IntAct (EBI)Q9BQ13
FunCoupENSG00000151364
BioGRIDKCTD14
STRING (EMBL)KCTD14
ZODIACKCTD14
Ontologies - Pathways
QuickGOQ9BQ13
Ontology : AmiGOprotein binding  protein homooligomerization  
Ontology : EGO-EBIprotein binding  protein homooligomerization  
NDEx NetworkKCTD14
Atlas of Cancer Signalling NetworkKCTD14
Wikipedia pathwaysKCTD14
Orthology - Evolution
OrthoDB65987
GeneTree (enSembl)ENSG00000151364
Phylogenetic Trees/Animal Genes : TreeFamKCTD14
HOVERGENQ9BQ13
HOGENOMQ9BQ13
Homologs : HomoloGeneKCTD14
Homology/Alignments : Family Browser (UCSC)KCTD14
Gene fusions - Rearrangements
Fusion : MitelmanINTS4/KCTD14 [11q14.1/11q14.1]  [t(11;11)(q14;q14)]  
Fusion : MitelmanKCNIP1/KCTD14 [5q35.1/11q14.1]  [t(5;11)(q35;q14)]  
Fusion : MitelmanPAK1/KCTD14 [11q13.5/11q14.1]  [t(11;11)(q14;q14)]  
Fusion : MitelmanTHRSP/KCTD14 [11q14.1/11q14.1]  [t(11;11)(q14;q14)]  
Fusion: TCGAINTS4 11q14.1 KCTD14 11q14.1 BRCA
Fusion: TCGAPAK1 11q13.5 KCTD14 11q14.1 BRCA
Fusion: TCGATHRSP 11q14.1 KCTD14 11q14.1 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCTD14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCTD14
dbVarKCTD14
ClinVarKCTD14
1000_GenomesKCTD14 
Exome Variant ServerKCTD14
ExAC (Exome Aggregation Consortium)KCTD14 (select the gene name)
Genetic variants : HAPMAP65987
Genomic Variants (DGV)KCTD14 [DGVbeta]
DECIPHERKCTD14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCTD14 
Mutations
ICGC Data PortalKCTD14 
TCGA Data PortalKCTD14 
Broad Tumor PortalKCTD14
OASIS PortalKCTD14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCTD14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCTD14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCTD14
DgiDB (Drug Gene Interaction Database)KCTD14
DoCM (Curated mutations)KCTD14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCTD14 (select a term)
intoGenKCTD14
Cancer3DKCTD14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenKCTD14
Genetic Testing Registry KCTD14
NextProtQ9BQ13 [Medical]
TSGene65987
GENETestsKCTD14
Target ValidationKCTD14
Huge Navigator KCTD14 [HugePedia]
snp3D : Map Gene to Disease65987
BioCentury BCIQKCTD14
ClinGenKCTD14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65987
Chemical/Pharm GKB GenePA134875104
Clinical trialKCTD14
Miscellaneous
canSAR (ICR)KCTD14 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCTD14
EVEXKCTD14
GoPubMedKCTD14
iHOPKCTD14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:14:15 CEST 2017

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