Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KCTD2 (potassium channel tetramerization domain containing 2)

Identity

Alias (NCBI)-
HGNC (Hugo) KCTD2
HGNC Alias symbKIAA0176
HGNC Previous namepotassium channel tetramerisation domain containing 2
LocusID (NCBI) 23510
Atlas_Id 54401
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75047225 and ends at 75065886 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C1orf50 (1p34.2) / KCTD2 (17q25.1)IL4I1 (19q13.33) / KCTD2 (17q25.1)KCTD2 (17q25.1) / ARHGEF12 (11q23.3)
KCTD2 (17q25.1) / KCTD2 (17q25.1)KCTD2 (17q25.1) / TMEM104 (17q25.1)NUP85 (17q25.1) / KCTD2 (17q25.1)
PDE4D (5q11.2) / KCTD2 (17q25.1)KCTD2 17q25.1 / TMEM104 17q25.1NUP85 17q25.1 / KCTD2 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)KCTD2   21294
Cards
Entrez_Gene (NCBI)KCTD2    potassium channel tetramerization domain containing 2
Aliases
GeneCards (Weizmann)KCTD2
Ensembl hg19 (Hinxton)ENSG00000180901 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180901 [Gene_View]  ENSG00000180901 [Sequence]  chr17:75047225-75065886 [Contig_View]  KCTD2 [Vega]
ICGC DataPortalENSG00000180901
TCGA cBioPortalKCTD2
AceView (NCBI)KCTD2
Genatlas (Paris)KCTD2
SOURCE (Princeton)KCTD2
Genetics Home Reference (NIH)KCTD2
Genomic and cartography
GoldenPath hg38 (UCSC)KCTD2  -     chr17:75047225-75065886 +  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCTD2  -     17q25.1   [Description]    (hg19-Feb_2009)
GoldenPathKCTD2 - 17q25.1 [CytoView hg19]  KCTD2 - 17q25.1 [CytoView hg38]
ImmunoBaseENSG00000180901
genome Data Viewer NCBIKCTD2 [Mapview hg19]  
OMIM613422   
Gene and transcription
Genbank (Entrez)AF055014 AI871166 AK307083 AK310690 AK311278
RefSeq transcript (Entrez)NM_015353
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCTD2
Alternative Splicing GalleryENSG00000180901
Gene ExpressionKCTD2 [ NCBI-GEO ]   KCTD2 [ EBI - ARRAY_EXPRESS ]   KCTD2 [ SEEK ]   KCTD2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCTD2 [ Firebrowse - Broad ]
GenevisibleExpression of KCTD2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23510
GTEX Portal (Tissue expression)KCTD2
Human Protein AtlasENSG00000180901-KCTD2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14681   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14681  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14681
Splice isoforms : SwissVarQ14681
PhosPhoSitePlusQ14681
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    T1-type_BTB   
Domain families : Pfam (Sanger)BTB_2 (PF02214)   
Domain families : Pfam (NCBI)pfam02214   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCTD2
Blocks (Seattle)KCTD2
SuperfamilyQ14681
Human Protein Atlas [tissue]ENSG00000180901-KCTD2 [tissue]
Peptide AtlasQ14681
HPRD17176
IPIIPI00455348   IPI00440769   
Protein Interaction databases
DIP (DOE-UCLA)Q14681
IntAct (EBI)Q14681
BioGRIDKCTD2
STRING (EMBL)KCTD2
ZODIACKCTD2
Ontologies - Pathways
QuickGOQ14681
Ontology : AmiGOcytoplasm  Cul3-RING ubiquitin ligase complex  proteasome-mediated ubiquitin-dependent protein catabolic process  protein-containing complex binding  protein homooligomerization  cullin family protein binding  
Ontology : EGO-EBIcytoplasm  Cul3-RING ubiquitin ligase complex  proteasome-mediated ubiquitin-dependent protein catabolic process  protein-containing complex binding  protein homooligomerization  cullin family protein binding  
NDEx NetworkKCTD2
Atlas of Cancer Signalling NetworkKCTD2
Wikipedia pathwaysKCTD2
Orthology - Evolution
OrthoDB23510
GeneTree (enSembl)ENSG00000180901
Phylogenetic Trees/Animal Genes : TreeFamKCTD2
HOGENOMQ14681
Homologs : HomoloGeneKCTD2
Homology/Alignments : Family Browser (UCSC)KCTD2
Gene fusions - Rearrangements
Fusion : MitelmanKCTD2/ARHGEF12 [17q25.1/11q23.3]  
Fusion : MitelmanKCTD2/TMEM104 [17q25.1/17q25.1]  
Fusion : MitelmanNUP85/KCTD2 [17q25.1/17q25.1]  
Fusion PortalKCTD2 17q25.1 TMEM104 17q25.1 LUAD
Fusion PortalNUP85 17q25.1 KCTD2 17q25.1 BLCA
Fusion : QuiverKCTD2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCTD2 [hg38]
dbVarKCTD2
ClinVarKCTD2
MonarchKCTD2
1000_GenomesKCTD2 
Exome Variant ServerKCTD2
GNOMAD BrowserENSG00000180901
Varsome BrowserKCTD2
Genomic Variants (DGV)KCTD2 [DGVbeta]
DECIPHERKCTD2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCTD2 
Mutations
ICGC Data PortalKCTD2 
TCGA Data PortalKCTD2 
Broad Tumor PortalKCTD2
OASIS PortalKCTD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCTD2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKCTD2
Mutations and Diseases : HGMDKCTD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCTD2
DgiDB (Drug Gene Interaction Database)KCTD2
DoCM (Curated mutations)KCTD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCTD2 (select a term)
intoGenKCTD2
Cancer3DKCTD2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613422   
Orphanet
DisGeNETKCTD2
MedgenKCTD2
Genetic Testing Registry KCTD2
NextProtQ14681 [Medical]
GENETestsKCTD2
Target ValidationKCTD2
Huge Navigator KCTD2 [HugePedia]
ClinGenKCTD2
Clinical trials, drugs, therapy
MyCancerGenomeKCTD2
Protein Interactions : CTD
Pharm GKB GenePA134890451
PharosQ14681
Clinical trialKCTD2
Miscellaneous
canSAR (ICR)KCTD2 (select the gene name)
HarmonizomeKCTD2
DataMed IndexKCTD2
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKCTD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:27:40 CET 2021
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.