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KCTD2 (potassium channel tetramerization domain containing 2)

Identity

Alias_namespotassium channel tetramerisation domain containing 2
Alias_symbol (synonym)KIAA0176
Other alias-
HGNC (Hugo) KCTD2
LocusID (NCBI) 23510
Atlas_Id 54401
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 73043279 and ends at 73061984 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
C1orf50 (1p34.2) / KCTD2 (17q25.1)IL4I1 (19q13.33) / KCTD2 (17q25.1)KCTD2 (17q25.1) / ARHGEF12 (11q23.3)
KCTD2 (17q25.1) / KCTD2 (17q25.1)KCTD2 (17q25.1) / TMEM104 (17q25.1)NUP85 (17q25.1) / KCTD2 (17q25.1)
PDE4D (5q11.2) / KCTD2 (17q25.1)KCTD2 17q25.1 / TMEM104 17q25.1NUP85 17q25.1 / KCTD2 17q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KCTD2   21294
Cards
Entrez_Gene (NCBI)KCTD2  23510  potassium channel tetramerization domain containing 2
Aliases
GeneCards (Weizmann)KCTD2
Ensembl hg19 (Hinxton)ENSG00000180901 [Gene_View]  chr17:73043279-73061984 [Contig_View]  KCTD2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000180901 [Gene_View]  chr17:73043279-73061984 [Contig_View]  KCTD2 [Vega]
ICGC DataPortalENSG00000180901
TCGA cBioPortalKCTD2
AceView (NCBI)KCTD2
Genatlas (Paris)KCTD2
WikiGenes23510
SOURCE (Princeton)KCTD2
Genetics Home Reference (NIH)KCTD2
Genomic and cartography
GoldenPath hg19 (UCSC)KCTD2  -     chr17:73043279-73061984 +  17q25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KCTD2  -     17q25.1   [Description]    (hg38-Dec_2013)
EnsemblKCTD2 - 17q25.1 [CytoView hg19]  KCTD2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBIKCTD2 [Mapview hg19]  KCTD2 [Mapview hg38]
OMIM613422   
Gene and transcription
Genbank (Entrez)AF055014 AI871166 AK307083 AK310690 AK311278
RefSeq transcript (Entrez)NM_015353
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)KCTD2
Cluster EST : UnigeneHs.733235 [ NCBI ]
CGAP (NCI)Hs.733235
Alternative Splicing GalleryENSG00000180901
Gene ExpressionKCTD2 [ NCBI-GEO ]   KCTD2 [ EBI - ARRAY_EXPRESS ]   KCTD2 [ SEEK ]   KCTD2 [ MEM ]
Gene Expression Viewer (FireBrowse)KCTD2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23510
GTEX Portal (Tissue expression)KCTD2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14681   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14681  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14681
Splice isoforms : SwissVarQ14681
PhosPhoSitePlusQ14681
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ    T1-type_BTB   
Domain families : Pfam (Sanger)BTB_2 (PF02214)   
Domain families : Pfam (NCBI)pfam02214   
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCTD2
DMDM Disease mutations23510
Blocks (Seattle)KCTD2
SuperfamilyQ14681
Human Protein AtlasENSG00000180901
Peptide AtlasQ14681
HPRD17176
IPIIPI00455348   IPI00440769   
Protein Interaction databases
DIP (DOE-UCLA)Q14681
IntAct (EBI)Q14681
FunCoupENSG00000180901
BioGRIDKCTD2
STRING (EMBL)KCTD2
ZODIACKCTD2
Ontologies - Pathways
QuickGOQ14681
Ontology : AmiGOprotein complex binding  protein homooligomerization  
Ontology : EGO-EBIprotein complex binding  protein homooligomerization  
NDEx NetworkKCTD2
Atlas of Cancer Signalling NetworkKCTD2
Wikipedia pathwaysKCTD2
Orthology - Evolution
OrthoDB23510
GeneTree (enSembl)ENSG00000180901
Phylogenetic Trees/Animal Genes : TreeFamKCTD2
HOVERGENQ14681
HOGENOMQ14681
Homologs : HomoloGeneKCTD2
Homology/Alignments : Family Browser (UCSC)KCTD2
Gene fusions - Rearrangements
Fusion : MitelmanKCTD2/ARHGEF12 [17q25.1/11q23.3]  
Fusion : MitelmanKCTD2/TMEM104 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion : MitelmanNUP85/KCTD2 [17q25.1/17q25.1]  [t(17;17)(q25;q25)]  
Fusion: TCGAKCTD2 17q25.1 TMEM104 17q25.1 LUAD
Fusion: TCGANUP85 17q25.1 KCTD2 17q25.1 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCTD2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCTD2
dbVarKCTD2
ClinVarKCTD2
1000_GenomesKCTD2 
Exome Variant ServerKCTD2
ExAC (Exome Aggregation Consortium)KCTD2 (select the gene name)
Genetic variants : HAPMAP23510
Genomic Variants (DGV)KCTD2 [DGVbeta]
DECIPHER (Syndromes)17:73043279-73061984  ENSG00000180901
CONAN: Copy Number AnalysisKCTD2 
Mutations
ICGC Data PortalKCTD2 
TCGA Data PortalKCTD2 
Broad Tumor PortalKCTD2
OASIS PortalKCTD2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCTD2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCTD2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCTD2
DgiDB (Drug Gene Interaction Database)KCTD2
DoCM (Curated mutations)KCTD2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCTD2 (select a term)
intoGenKCTD2
Cancer3DKCTD2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613422   
Orphanet
MedgenKCTD2
Genetic Testing Registry KCTD2
NextProtQ14681 [Medical]
TSGene23510
GENETestsKCTD2
Huge Navigator KCTD2 [HugePedia]
snp3D : Map Gene to Disease23510
BioCentury BCIQKCTD2
ClinGenKCTD2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23510
Chemical/Pharm GKB GenePA134890451
Clinical trialKCTD2
Miscellaneous
canSAR (ICR)KCTD2 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCTD2
EVEXKCTD2
GoPubMedKCTD2
iHOPKCTD2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:05:59 CEST 2017

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