Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KCTD20 (potassium channel tetramerization domain containing 20)

Identity

Other aliasC6orf69
dJ108K11.3
HGNC (Hugo) KCTD20
LocusID (NCBI) 222658
Atlas_Id 57083
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 36442767 and ends at 36491143 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCTD20 (6p21.31) / ETV7 (6p21.31)KCTD20 (6p21.31) / JARID2 (6p22.3)KCTD20 (6p21.31) / STK38 (6p21.31)
PARP12 (7q34) / KCTD20 (6p21.31)USP49 (6p21.1) / KCTD20 (6p21.31)ZFAND3 (6p21.2) / KCTD20 (6p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  KCTD20/ETV7 (6p21)
KCTD20/STK38 (6p21)
USP49/KCTD20 (6p21)
ZFAND3/KCTD20 (6p21)
t(6;6)(p21;p22) KCTD20/JARID2

External links

Nomenclature
HGNC (Hugo)KCTD20   21052
Cards
Entrez_Gene (NCBI)KCTD20  222658  potassium channel tetramerization domain containing 20
AliasesC6orf69; dJ108K11.3
GeneCards (Weizmann)KCTD20
Ensembl hg19 (Hinxton)ENSG00000112078 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112078 [Gene_View]  ENSG00000112078 [Sequence]  chr6:36442767-36491143 [Contig_View]  KCTD20 [Vega]
ICGC DataPortalENSG00000112078
TCGA cBioPortalKCTD20
AceView (NCBI)KCTD20
Genatlas (Paris)KCTD20
WikiGenes222658
SOURCE (Princeton)KCTD20
Genetics Home Reference (NIH)KCTD20
Genomic and cartography
GoldenPath hg38 (UCSC)KCTD20  -     chr6:36442767-36491143 +  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCTD20  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblKCTD20 - 6p21.31 [CytoView hg19]  KCTD20 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBIKCTD20 [Mapview hg19]  KCTD20 [Mapview hg38]
OMIM615932   
Gene and transcription
Genbank (Entrez)AK295717 AK302861 AK304377 AK316456 AL049282
RefSeq transcript (Entrez)NM_001286579 NM_001286580 NM_173562
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCTD20
Cluster EST : UnigeneHs.188757 [ NCBI ]
CGAP (NCI)Hs.188757
Alternative Splicing GalleryENSG00000112078
Gene ExpressionKCTD20 [ NCBI-GEO ]   KCTD20 [ EBI - ARRAY_EXPRESS ]   KCTD20 [ SEEK ]   KCTD20 [ MEM ]
Gene Expression Viewer (FireBrowse)KCTD20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)222658
GTEX Portal (Tissue expression)KCTD20
Human Protein AtlasENSG00000112078-KCTD20 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5Y7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z5Y7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z5Y7
Splice isoforms : SwissVarQ7Z5Y7
PhosPhoSitePlusQ7Z5Y7
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)BTB (SM00225)  
Conserved Domain (NCBI)KCTD20
DMDM Disease mutations222658
Blocks (Seattle)KCTD20
SuperfamilyQ7Z5Y7
Human Protein Atlas [tissue]ENSG00000112078-KCTD20 [tissue]
Peptide AtlasQ7Z5Y7
IPIIPI00796097   IPI00418430   IPI01010159   IPI01011165   IPI00947232   IPI00945817   IPI00945070   IPI00947420   IPI00945047   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5Y7
IntAct (EBI)Q7Z5Y7
FunCoupENSG00000112078
BioGRIDKCTD20
STRING (EMBL)KCTD20
ZODIACKCTD20
Ontologies - Pathways
QuickGOQ7Z5Y7
Ontology : AmiGOcytoplasm  positive regulation of phosphorylation  
Ontology : EGO-EBIcytoplasm  positive regulation of phosphorylation  
NDEx NetworkKCTD20
Atlas of Cancer Signalling NetworkKCTD20
Wikipedia pathwaysKCTD20
Orthology - Evolution
OrthoDB222658
GeneTree (enSembl)ENSG00000112078
Phylogenetic Trees/Animal Genes : TreeFamKCTD20
HOGENOMQ7Z5Y7
Homologs : HomoloGeneKCTD20
Homology/Alignments : Family Browser (UCSC)KCTD20
Gene fusions - Rearrangements
Fusion : QuiverKCTD20
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCTD20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCTD20
dbVarKCTD20
ClinVarKCTD20
1000_GenomesKCTD20 
Exome Variant ServerKCTD20
ExAC (Exome Aggregation Consortium)ENSG00000112078
GNOMAD BrowserENSG00000112078
Varsome BrowserKCTD20
Genetic variants : HAPMAP222658
Genomic Variants (DGV)KCTD20 [DGVbeta]
DECIPHERKCTD20 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCTD20 
Mutations
ICGC Data PortalKCTD20 
TCGA Data PortalKCTD20 
Broad Tumor PortalKCTD20
OASIS PortalKCTD20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCTD20  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCTD20
BioMutasearch KCTD20
DgiDB (Drug Gene Interaction Database)KCTD20
DoCM (Curated mutations)KCTD20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCTD20 (select a term)
intoGenKCTD20
Cancer3DKCTD20(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615932   
Orphanet
DisGeNETKCTD20
MedgenKCTD20
Genetic Testing Registry KCTD20
NextProtQ7Z5Y7 [Medical]
TSGene222658
GENETestsKCTD20
Target ValidationKCTD20
Huge Navigator KCTD20 [HugePedia]
snp3D : Map Gene to Disease222658
BioCentury BCIQKCTD20
ClinGenKCTD20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD222658
Chemical/Pharm GKB GenePA134913479
Clinical trialKCTD20
Miscellaneous
canSAR (ICR)KCTD20 (select the gene name)
DataMed IndexKCTD20
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCTD20
EVEXKCTD20
GoPubMedKCTD20
iHOPKCTD20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 17 18:19:02 CET 2019
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