Atlas of Genetics and Cytogenetics in Oncology and Haematology

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KCTD3 (potassium channel tetramerization domain containing 3)

Identity

Alias_namespotassium channel tetramerisation domain containing 3
Alias_symbol (synonym)NY-REN-45
Other alias
HGNC (Hugo) KCTD3
LocusID (NCBI) 51133
Atlas_Id 41054
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 215567379 and ends at 215621821 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KCTD3 (1q41) / KCTD3 (1q41)KCTD3 (1q41) / TACC3 (4p16.3)KCTD3 (1q41) / TXNDC16 (14q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;14)(q41;q22) KCTD3/TXNDC16

External links

Nomenclature
HGNC (Hugo)KCTD3   21305
Cards
Entrez_Gene (NCBI)KCTD3  51133  potassium channel tetramerization domain containing 3
AliasesNY-REN-45
GeneCards (Weizmann)KCTD3
Ensembl hg19 (Hinxton)ENSG00000136636 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136636 [Gene_View]  ENSG00000136636 [Sequence]  chr1:215567379-215621821 [Contig_View]  KCTD3 [Vega]
ICGC DataPortalENSG00000136636
TCGA cBioPortalKCTD3
AceView (NCBI)KCTD3
Genatlas (Paris)KCTD3
WikiGenes51133
SOURCE (Princeton)KCTD3
Genetics Home Reference (NIH)KCTD3
Genomic and cartography
GoldenPath hg38 (UCSC)KCTD3  -     chr1:215567379-215621821 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KCTD3  -     1q41   [Description]    (hg19-Feb_2009)
EnsemblKCTD3 - 1q41 [CytoView hg19]  KCTD3 - 1q41 [CytoView hg38]
Mapping of homologs : NCBIKCTD3 [Mapview hg19]  KCTD3 [Mapview hg38]
OMIM613272   
Gene and transcription
Genbank (Entrez)AK024547 AK055925 AK296275 AK316272 AL833887
RefSeq transcript (Entrez)NM_001319294 NM_001319295 NM_016121
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KCTD3
Cluster EST : UnigeneHs.335139 [ NCBI ]
CGAP (NCI)Hs.335139
Alternative Splicing GalleryENSG00000136636
Gene ExpressionKCTD3 [ NCBI-GEO ]   KCTD3 [ EBI - ARRAY_EXPRESS ]   KCTD3 [ SEEK ]   KCTD3 [ MEM ]
Gene Expression Viewer (FireBrowse)KCTD3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51133
GTEX Portal (Tissue expression)KCTD3
Human Protein AtlasENSG00000136636-KCTD3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y597   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y597  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y597
Splice isoforms : SwissVarQ9Y597
PhosPhoSitePlusQ9Y597
Domaine pattern : Prosite (Expaxy)BTB (PS50097)    WD_REPEATS_1 (PS00678)   
Domains : Interpro (EBI)BTB/POZ_dom    SKP1/BTB/POZ_sf    T1-type_BTB    WD40/YVTN_repeat-like_dom_sf    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom_sf   
Domain families : Pfam (Sanger)BTB_2 (PF02214)   
Domain families : Pfam (NCBI)pfam02214   
Domain families : Smart (EMBL)BTB (SM00225)  WD40 (SM00320)  
Conserved Domain (NCBI)KCTD3
DMDM Disease mutations51133
Blocks (Seattle)KCTD3
SuperfamilyQ9Y597
Human Protein Atlas [tissue]ENSG00000136636-KCTD3 [tissue]
Peptide AtlasQ9Y597
HPRD13766
IPIIPI00410103   IPI00783521   IPI00783650   IPI00478748   IPI00480013   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y597
IntAct (EBI)Q9Y597
FunCoupENSG00000136636
BioGRIDKCTD3
STRING (EMBL)KCTD3
ZODIACKCTD3
Ontologies - Pathways
QuickGOQ9Y597
Ontology : AmiGOplasma membrane  protein homooligomerization  
Ontology : EGO-EBIplasma membrane  protein homooligomerization  
NDEx NetworkKCTD3
Atlas of Cancer Signalling NetworkKCTD3
Wikipedia pathwaysKCTD3
Orthology - Evolution
OrthoDB51133
GeneTree (enSembl)ENSG00000136636
Phylogenetic Trees/Animal Genes : TreeFamKCTD3
HOVERGENQ9Y597
HOGENOMQ9Y597
Homologs : HomoloGeneKCTD3
Homology/Alignments : Family Browser (UCSC)KCTD3
Gene fusions - Rearrangements
Fusion : MitelmanKCTD3/TXNDC16 [1q41/14q22.1]  
Fusion : QuiverKCTD3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKCTD3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KCTD3
dbVarKCTD3
ClinVarKCTD3
1000_GenomesKCTD3 
Exome Variant ServerKCTD3
ExAC (Exome Aggregation Consortium)ENSG00000136636
GNOMAD BrowserENSG00000136636
Varsome BrowserKCTD3
Genetic variants : HAPMAP51133
Genomic Variants (DGV)KCTD3 [DGVbeta]
DECIPHERKCTD3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKCTD3 
Mutations
ICGC Data PortalKCTD3 
TCGA Data PortalKCTD3 
Broad Tumor PortalKCTD3
OASIS PortalKCTD3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKCTD3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKCTD3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KCTD3
DgiDB (Drug Gene Interaction Database)KCTD3
DoCM (Curated mutations)KCTD3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KCTD3 (select a term)
intoGenKCTD3
Cancer3DKCTD3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613272   
Orphanet
DisGeNETKCTD3
MedgenKCTD3
Genetic Testing Registry KCTD3
NextProtQ9Y597 [Medical]
TSGene51133
GENETestsKCTD3
Target ValidationKCTD3
Huge Navigator KCTD3 [HugePedia]
snp3D : Map Gene to Disease51133
BioCentury BCIQKCTD3
ClinGenKCTD3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51133
Chemical/Pharm GKB GenePA134945859
Clinical trialKCTD3
Miscellaneous
canSAR (ICR)KCTD3 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKCTD3
EVEXKCTD3
GoPubMedKCTD3
iHOPKCTD3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:14:44 CET 2018
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