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KDM3A (lysine demethylase 3A)

Identity

Alias (NCBI)JHDM2A
JHMD2A
JMJD1
JMJD1A
TSGA
HGNC (Hugo) KDM3A
HGNC Alias symbTSGA
KIAA0742
JHMD2A
HGNC Alias namejumonji C domain-containing histone demethylase 2A
HGNC Previous nameJMJD1
 JMJD1A
HGNC Previous namejumonji domain containing 1
 jumonji domain containing 1A
 lysine (K)-specific demethylase 3A
LocusID (NCBI) 55818
Atlas_Id 51339
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 86441371 and ends at 86492716 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTR3 (2q14.1) / KDM3A (2p11.2)ADCY1 (7p12.3) / KDM3A (2p11.2)KDM3A (2p11.2) / ADCY1 (7p12.3)
KDM3A (2p11.2) / PUS10 (2p16.1)KDM3A (2p11.2) / RFX8 (2q11.2)PARD3 (10p11.22) / KDM3A (2p11.2)
KDM3A 2p11.2 / PUS10 2p16.1KDM3A 2p11.2 / RFX8 2q11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KDM3A   20815
Cards
Entrez_Gene (NCBI)KDM3A    lysine demethylase 3A
AliasesJHDM2A; JHMD2A; JMJD1; JMJD1A; 
TSGA
GeneCards (Weizmann)KDM3A
Ensembl hg19 (Hinxton)ENSG00000115548 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115548 [Gene_View]  ENSG00000115548 [Sequence]  chr2:86441371-86492716 [Contig_View]  KDM3A [Vega]
ICGC DataPortalENSG00000115548
TCGA cBioPortalKDM3A
AceView (NCBI)KDM3A
Genatlas (Paris)KDM3A
SOURCE (Princeton)KDM3A
Genetics Home Reference (NIH)KDM3A
Genomic and cartography
GoldenPath hg38 (UCSC)KDM3A  -     chr2:86441371-86492716 +  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KDM3A  -     2p11.2   [Description]    (hg19-Feb_2009)
GoldenPathKDM3A - 2p11.2 [CytoView hg19]  KDM3A - 2p11.2 [CytoView hg38]
ImmunoBaseENSG00000115548
Genome Data Viewer NCBIKDM3A [Mapview hg19]  
OMIM611512   
Gene and transcription
Genbank (Entrez)AB018285 AI911797 AK074314 AK125045 AK304276
RefSeq transcript (Entrez)NM_001146688 NM_018433
Consensus coding sequences : CCDS (NCBI)KDM3A
Gene ExpressionKDM3A [ NCBI-GEO ]   KDM3A [ EBI - ARRAY_EXPRESS ]   KDM3A [ SEEK ]   KDM3A [ MEM ]
Gene Expression Viewer (FireBrowse)KDM3A [ Firebrowse - Broad ]
GenevisibleExpression of KDM3A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55818
GTEX Portal (Tissue expression)KDM3A
Human Protein AtlasENSG00000115548-KDM3A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4C1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4C1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4C1
PhosPhoSitePlusQ9Y4C1
Domaine pattern : Prosite (Expaxy)JMJC (PS51184)   
Domains : Interpro (EBI)JmjC_dom   
Domain families : Pfam (Sanger)JmjC (PF02373)   
Domain families : Pfam (NCBI)pfam02373   
Domain families : Smart (EMBL)JmjC (SM00558)  
Conserved Domain (NCBI)KDM3A
SuperfamilyQ9Y4C1
AlphaFold pdb e-kbQ9Y4C1   
Human Protein Atlas [tissue]ENSG00000115548-KDM3A [tissue]
HPRD11054
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4C1
IntAct (EBI)Q9Y4C1
BioGRIDKDM3A
STRING (EMBL)KDM3A
ZODIACKDM3A
Ontologies - Pathways
QuickGOQ9Y4C1
Ontology : AmiGOhistone deacetylase complex  chromatin  transcription coregulator activity  iron ion binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  spermatid nucleus elongation  hormone-mediated signaling pathway  membrane  androgen receptor signaling pathway  intracellular receptor signaling pathway  chromatin DNA binding  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  histone H3-K9 demethylation  histone H3-K9 demethylation  histone H3-K9 dimethylation  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  formaldehyde biosynthetic process  androgen receptor binding  dioxygenase activity  negative regulation of histone H3-K9 methylation  positive regulation of cold-induced thermogenesis  cellular response to leukemia inhibitory factor  regulation of stem cell population maintenance  regulation of stem cell differentiation  
Ontology : EGO-EBIhistone deacetylase complex  chromatin  transcription coregulator activity  iron ion binding  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  regulation of transcription by RNA polymerase II  spermatid nucleus elongation  hormone-mediated signaling pathway  membrane  androgen receptor signaling pathway  intracellular receptor signaling pathway  chromatin DNA binding  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  histone H3-K9 demethylation  histone H3-K9 demethylation  histone H3-K9 dimethylation  positive regulation of transcription, DNA-templated  positive regulation of transcription by RNA polymerase II  formaldehyde biosynthetic process  androgen receptor binding  dioxygenase activity  negative regulation of histone H3-K9 methylation  positive regulation of cold-induced thermogenesis  cellular response to leukemia inhibitory factor  regulation of stem cell population maintenance  regulation of stem cell differentiation  
NDEx NetworkKDM3A
Atlas of Cancer Signalling NetworkKDM3A
Wikipedia pathwaysKDM3A
Orthology - Evolution
OrthoDB55818
GeneTree (enSembl)ENSG00000115548
Phylogenetic Trees/Animal Genes : TreeFamKDM3A
Homologs : HomoloGeneKDM3A
Homology/Alignments : Family Browser (UCSC)KDM3A
Gene fusions - Rearrangements
Fusion : MitelmanKDM3A/PUS10 [2p11.2/2p16.1]  
Fusion : MitelmanKDM3A/RFX8 [2p11.2/2q11.2]  
Fusion : QuiverKDM3A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKDM3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KDM3A
dbVarKDM3A
ClinVarKDM3A
MonarchKDM3A
1000_GenomesKDM3A 
Exome Variant ServerKDM3A
GNOMAD BrowserENSG00000115548
Varsome BrowserKDM3A
ACMGKDM3A variants
VarityQ9Y4C1
Genomic Variants (DGV)KDM3A [DGVbeta]
DECIPHERKDM3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKDM3A 
Mutations
ICGC Data PortalKDM3A 
TCGA Data PortalKDM3A 
Broad Tumor PortalKDM3A
OASIS PortalKDM3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKDM3A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKDM3A
Mutations and Diseases : HGMDKDM3A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKDM3A
DgiDB (Drug Gene Interaction Database)KDM3A
DoCM (Curated mutations)KDM3A
CIViC (Clinical Interpretations of Variants in Cancer)KDM3A
Cancer3DKDM3A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611512   
Orphanet
DisGeNETKDM3A
MedgenKDM3A
Genetic Testing Registry KDM3A
NextProtQ9Y4C1 [Medical]
GENETestsKDM3A
Target ValidationKDM3A
Huge Navigator KDM3A [HugePedia]
ClinGenKDM3A
Clinical trials, drugs, therapy
MyCancerGenomeKDM3A
Protein Interactions : CTDKDM3A
Pharm GKB GenePA164721293
PharosQ9Y4C1
Clinical trialKDM3A
Miscellaneous
canSAR (ICR)KDM3A
HarmonizomeKDM3A
DataMed IndexKDM3A
Probes
Litterature
PubMed92 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKDM3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:14:51 CEST 2021

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