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KDM4E (lysine demethylase 4E)

Identity

Alias (NCBI)JMJD2E
KDM4DL
KDM5E
HGNC (Hugo) KDM4E
HGNC Alias symbJMJD2E
HGNC Previous nameKDM4DL
HGNC Previous namelysine (K)-specific demethylase 4D-like
 lysine (K)-specific demethylase 4E
LocusID (NCBI) 390245
Atlas_Id 64837
Location 11q21  [Link to chromosome band 11q21]
Location_base_pair Starts at 95025258 and ends at 95027596 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KDM4E   37098
Cards
Entrez_Gene (NCBI)KDM4E    lysine demethylase 4E
AliasesJMJD2E; KDM4DL; KDM5E
GeneCards (Weizmann)KDM4E
Ensembl hg19 (Hinxton)ENSG00000235268 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000235268 [Gene_View]  ENSG00000235268 [Sequence]  chr11:95025258-95027596 [Contig_View]  KDM4E [Vega]
ICGC DataPortalENSG00000235268
TCGA cBioPortalKDM4E
AceView (NCBI)KDM4E
Genatlas (Paris)KDM4E
SOURCE (Princeton)KDM4E
Genetics Home Reference (NIH)KDM4E
Genomic and cartography
GoldenPath hg38 (UCSC)KDM4E  -     chr11:95025258-95027596 +  11q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KDM4E  -     11q21   [Description]    (hg19-Feb_2009)
GoldenPathKDM4E - 11q21 [CytoView hg19]  KDM4E - 11q21 [CytoView hg38]
ImmunoBaseENSG00000235268
Genome Data Viewer NCBIKDM4E [Mapview hg19]  
OMIM616581   
Gene and transcription
Genbank (Entrez)BC157851 BC157889 BC171916
RefSeq transcript (Entrez)NM_001161630
Consensus coding sequences : CCDS (NCBI)KDM4E
Gene ExpressionKDM4E [ NCBI-GEO ]   KDM4E [ EBI - ARRAY_EXPRESS ]   KDM4E [ SEEK ]   KDM4E [ MEM ]
Gene Expression Viewer (FireBrowse)KDM4E [ Firebrowse - Broad ]
GenevisibleExpression of KDM4E in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)390245
GTEX Portal (Tissue expression)KDM4E
Human Protein AtlasENSG00000235268-KDM4E [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtB2RXH2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtB2RXH2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProB2RXH2
PhosPhoSitePlusB2RXH2
Domaine pattern : Prosite (Expaxy)JMJC (PS51184)    JMJN (PS51183)   
Domains : Interpro (EBI)JmjC_dom    JmjN   
Domain families : Pfam (Sanger)JmjC (PF02373)    JmjN (PF02375)   
Domain families : Pfam (NCBI)pfam02373    pfam02375   
Domain families : Smart (EMBL)JmjC (SM00558)  JmjN (SM00545)  
Conserved Domain (NCBI)KDM4E
PDB (RSDB)2W2I   
PDB Europe2W2I   
PDB (PDBSum)2W2I   
PDB (IMB)2W2I   
Structural Biology KnowledgeBase2W2I   
SCOP (Structural Classification of Proteins)2W2I   
CATH (Classification of proteins structures)2W2I   
SuperfamilyB2RXH2
AlphaFold pdb e-kbB2RXH2   
Human Protein Atlas [tissue]ENSG00000235268-KDM4E [tissue]
Protein Interaction databases
DIP (DOE-UCLA)B2RXH2
IntAct (EBI)B2RXH2
BioGRIDKDM4E
STRING (EMBL)KDM4E
ZODIACKDM4E
Ontologies - Pathways
QuickGOB2RXH2
Ontology : AmiGOnucleus  nucleus  chromatin remodeling  histone demethylase activity  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  metal ion binding  dioxygenase activity  
Ontology : EGO-EBInucleus  nucleus  chromatin remodeling  histone demethylase activity  histone demethylase activity (H3-K9 specific)  histone demethylase activity (H3-K9 specific)  histone H3-K9 demethylation  metal ion binding  dioxygenase activity  
NDEx NetworkKDM4E
Atlas of Cancer Signalling NetworkKDM4E
Wikipedia pathwaysKDM4E
Orthology - Evolution
OrthoDB390245
GeneTree (enSembl)ENSG00000235268
Phylogenetic Trees/Animal Genes : TreeFamKDM4E
Homologs : HomoloGeneKDM4E
Homology/Alignments : Family Browser (UCSC)KDM4E
Gene fusions - Rearrangements
Fusion : QuiverKDM4E
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKDM4E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KDM4E
dbVarKDM4E
ClinVarKDM4E
MonarchKDM4E
1000_GenomesKDM4E 
Exome Variant ServerKDM4E
GNOMAD BrowserENSG00000235268
Varsome BrowserKDM4E
ACMGKDM4E variants
VarityB2RXH2
Genomic Variants (DGV)KDM4E [DGVbeta]
DECIPHERKDM4E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKDM4E 
Mutations
ICGC Data PortalKDM4E 
TCGA Data PortalKDM4E 
Broad Tumor PortalKDM4E
OASIS PortalKDM4E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKDM4E  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKDM4E
Mutations and Diseases : HGMDKDM4E
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKDM4E
DgiDB (Drug Gene Interaction Database)KDM4E
DoCM (Curated mutations)KDM4E
CIViC (Clinical Interpretations of Variants in Cancer)KDM4E
Cancer3DKDM4E
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616581   
Orphanet
DisGeNETKDM4E
MedgenKDM4E
Genetic Testing Registry KDM4E
NextProtB2RXH2 [Medical]
GENETestsKDM4E
Target ValidationKDM4E
Huge Navigator KDM4E [HugePedia]
ClinGenKDM4E
Clinical trials, drugs, therapy
MyCancerGenomeKDM4E
Protein Interactions : CTDKDM4E
Pharm GKB GenePA165543440
PharosB2RXH2
Clinical trialKDM4E
Miscellaneous
canSAR (ICR)KDM4E
HarmonizomeKDM4E
DataMed IndexKDM4E
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKDM4E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:54:29 CEST 2021

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