Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KDM4E (lysine demethylase 4E)

Identity

Alias_namesKDM4DL
lysine (K)-specific demethylase 4D-like
lysine (K)-specific demethylase 4E
Alias_symbol (synonym)JMJD2E
Other aliasKDM5E
HGNC (Hugo) KDM4E
LocusID (NCBI) 390245
Atlas_Id 64837
Location 11q21  [Link to chromosome band 11q21]
Location_base_pair Starts at 95025258 and ends at 95027596 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KDM4E   37098
Cards
Entrez_Gene (NCBI)KDM4E  390245  lysine demethylase 4E
AliasesJMJD2E; KDM4DL; KDM5E
GeneCards (Weizmann)KDM4E
Ensembl hg19 (Hinxton)ENSG00000235268 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000235268 [Gene_View]  chr11:95025258-95027596 [Contig_View]  KDM4E [Vega]
ICGC DataPortalENSG00000235268
TCGA cBioPortalKDM4E
AceView (NCBI)KDM4E
Genatlas (Paris)KDM4E
WikiGenes390245
SOURCE (Princeton)KDM4E
Genetics Home Reference (NIH)KDM4E
Genomic and cartography
GoldenPath hg38 (UCSC)KDM4E  -     chr11:95025258-95027596 +  11q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KDM4E  -     11q21   [Description]    (hg19-Feb_2009)
EnsemblKDM4E - 11q21 [CytoView hg19]  KDM4E - 11q21 [CytoView hg38]
Mapping of homologs : NCBIKDM4E [Mapview hg19]  KDM4E [Mapview hg38]
OMIM616581   
Gene and transcription
Genbank (Entrez)BC157851 BC157889 BC171916
RefSeq transcript (Entrez)NM_001161630
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KDM4E
Cluster EST : UnigeneHs.714692 [ NCBI ]
CGAP (NCI)Hs.714692
Alternative Splicing GalleryENSG00000235268
Gene ExpressionKDM4E [ NCBI-GEO ]   KDM4E [ EBI - ARRAY_EXPRESS ]   KDM4E [ SEEK ]   KDM4E [ MEM ]
Gene Expression Viewer (FireBrowse)KDM4E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)390245
GTEX Portal (Tissue expression)KDM4E
Protein : pattern, domain, 3D structure
UniProt/SwissProtB2RXH2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtB2RXH2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProB2RXH2
Splice isoforms : SwissVarB2RXH2
Catalytic activity : Enzyme1.14.11.- [ Enzyme-Expasy ]   1.14.11.-1.14.11.- [ IntEnz-EBI ]   1.14.11.- [ BRENDA ]   1.14.11.- [ KEGG ]   
PhosPhoSitePlusB2RXH2
Domaine pattern : Prosite (Expaxy)JMJC (PS51184)    JMJN (PS51183)   
Domains : Interpro (EBI)JmjC_dom    JmjN   
Domain families : Pfam (Sanger)JmjC (PF02373)    JmjN (PF02375)   
Domain families : Pfam (NCBI)pfam02373    pfam02375   
Domain families : Smart (EMBL)JmjC (SM00558)  JmjN (SM00545)  
Conserved Domain (NCBI)KDM4E
DMDM Disease mutations390245
Blocks (Seattle)KDM4E
PDB (SRS)2W2I   
PDB (PDBSum)2W2I   
PDB (IMB)2W2I   
PDB (RSDB)2W2I   
Structural Biology KnowledgeBase2W2I   
SCOP (Structural Classification of Proteins)2W2I   
CATH (Classification of proteins structures)2W2I   
SuperfamilyB2RXH2
Human Protein AtlasENSG00000235268
Peptide AtlasB2RXH2
IPIIPI00887640   
Protein Interaction databases
DIP (DOE-UCLA)B2RXH2
IntAct (EBI)B2RXH2
FunCoupENSG00000235268
BioGRIDKDM4E
STRING (EMBL)KDM4E
ZODIACKDM4E
Ontologies - Pathways
QuickGOB2RXH2
Ontology : AmiGOnucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  covalent chromatin modification  metal ion binding  dioxygenase activity  oxidation-reduction process  
Ontology : EGO-EBInucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  covalent chromatin modification  metal ion binding  dioxygenase activity  oxidation-reduction process  
NDEx NetworkKDM4E
Atlas of Cancer Signalling NetworkKDM4E
Wikipedia pathwaysKDM4E
Orthology - Evolution
OrthoDB390245
GeneTree (enSembl)ENSG00000235268
Phylogenetic Trees/Animal Genes : TreeFamKDM4E
HOVERGENB2RXH2
HOGENOMB2RXH2
Homologs : HomoloGeneKDM4E
Homology/Alignments : Family Browser (UCSC)KDM4E
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKDM4E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KDM4E
dbVarKDM4E
ClinVarKDM4E
1000_GenomesKDM4E 
Exome Variant ServerKDM4E
ExAC (Exome Aggregation Consortium)KDM4E (select the gene name)
Genetic variants : HAPMAP390245
Genomic Variants (DGV)KDM4E [DGVbeta]
DECIPHERKDM4E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKDM4E 
Mutations
ICGC Data PortalKDM4E 
TCGA Data PortalKDM4E 
Broad Tumor PortalKDM4E
OASIS PortalKDM4E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKDM4E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKDM4E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KDM4E
DgiDB (Drug Gene Interaction Database)KDM4E
DoCM (Curated mutations)KDM4E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KDM4E (select a term)
intoGenKDM4E
Cancer3DKDM4E(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616581   
Orphanet
MedgenKDM4E
Genetic Testing Registry KDM4E
NextProtB2RXH2 [Medical]
TSGene390245
GENETestsKDM4E
Target ValidationKDM4E
Huge Navigator KDM4E [HugePedia]
snp3D : Map Gene to Disease390245
BioCentury BCIQKDM4E
ClinGenKDM4E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD390245
Chemical/Pharm GKB GenePA165543440
Clinical trialKDM4E
Miscellaneous
canSAR (ICR)KDM4E (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKDM4E
EVEXKDM4E
GoPubMedKDM4E
iHOPKDM4E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:54:19 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.