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KERA (keratocan)

Identity

Alias_namesCNA2
Alias_symbol (synonym)SLRR2B
Other aliasKTN
HGNC (Hugo) KERA
LocusID (NCBI) 11081
Atlas_Id 64839
Location 12q21.33  [Link to chromosome band 12q21]
Location_base_pair Starts at 91050494 and ends at 91058354 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KERA   6309
LRG (Locus Reference Genomic)LRG_538
Cards
Entrez_Gene (NCBI)KERA  11081  keratocan
AliasesCNA2; KTN; SLRR2B
GeneCards (Weizmann)KERA
Ensembl hg19 (Hinxton)ENSG00000139330 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139330 [Gene_View]  chr12:91050494-91058354 [Contig_View]  KERA [Vega]
ICGC DataPortalENSG00000139330
TCGA cBioPortalKERA
AceView (NCBI)KERA
Genatlas (Paris)KERA
WikiGenes11081
SOURCE (Princeton)KERA
Genetics Home Reference (NIH)KERA
Genomic and cartography
GoldenPath hg38 (UCSC)KERA  -     chr12:91050494-91058354 -  12q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KERA  -     12q21.33   [Description]    (hg19-Feb_2009)
EnsemblKERA - 12q21.33 [CytoView hg19]  KERA - 12q21.33 [CytoView hg38]
Mapping of homologs : NCBIKERA [Mapview hg19]  KERA [Mapview hg38]
OMIM217300   603288   
Gene and transcription
Genbank (Entrez)AF063301 AF205403 AK314990 BC032667 BM722433
RefSeq transcript (Entrez)NM_007035
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KERA
Cluster EST : UnigeneHs.125750 [ NCBI ]
CGAP (NCI)Hs.125750
Alternative Splicing GalleryENSG00000139330
Gene ExpressionKERA [ NCBI-GEO ]   KERA [ EBI - ARRAY_EXPRESS ]   KERA [ SEEK ]   KERA [ MEM ]
Gene Expression Viewer (FireBrowse)KERA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11081
GTEX Portal (Tissue expression)KERA
Human Protein AtlasENSG00000139330-KERA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60938   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60938  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60938
Splice isoforms : SwissVarO60938
PhosPhoSitePlusO60938
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)L_dom-like    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRRNT   
Domain families : Pfam (Sanger)LRR_6 (PF13516)    LRR_8 (PF13855)   
Domain families : Pfam (NCBI)pfam13516    pfam13855   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
Conserved Domain (NCBI)KERA
DMDM Disease mutations11081
Blocks (Seattle)KERA
SuperfamilyO60938
Human Protein Atlas [tissue]ENSG00000139330-KERA [tissue]
Peptide AtlasO60938
HPRD04477
IPIIPI00013049   
Protein Interaction databases
DIP (DOE-UCLA)O60938
IntAct (EBI)O60938
FunCoupENSG00000139330
BioGRIDKERA
STRING (EMBL)KERA
ZODIACKERA
Ontologies - Pathways
QuickGOO60938
Ontology : AmiGOmolecular_function  extracellular region  proteinaceous extracellular matrix  proteinaceous extracellular matrix  extracellular space  Golgi lumen  axonogenesis  visual perception  keratan sulfate biosynthetic process  keratan sulfate catabolic process  lysosomal lumen  response to stimulus  cornea development in camera-type eye  
Ontology : EGO-EBImolecular_function  extracellular region  proteinaceous extracellular matrix  proteinaceous extracellular matrix  extracellular space  Golgi lumen  axonogenesis  visual perception  keratan sulfate biosynthetic process  keratan sulfate catabolic process  lysosomal lumen  response to stimulus  cornea development in camera-type eye  
Pathways : BIOCARTASmall Leucine-rich Proteoglycan (SLRP) molecules [Genes]   
NDEx NetworkKERA
Atlas of Cancer Signalling NetworkKERA
Wikipedia pathwaysKERA
Orthology - Evolution
OrthoDB11081
GeneTree (enSembl)ENSG00000139330
Phylogenetic Trees/Animal Genes : TreeFamKERA
HOVERGENO60938
HOGENOMO60938
Homologs : HomoloGeneKERA
Homology/Alignments : Family Browser (UCSC)KERA
Gene fusions - Rearrangements
Tumor Fusion PortalKERA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKERA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KERA
dbVarKERA
ClinVarKERA
1000_GenomesKERA 
Exome Variant ServerKERA
ExAC (Exome Aggregation Consortium)ENSG00000139330
GNOMAD BrowserENSG00000139330
Genetic variants : HAPMAP11081
Genomic Variants (DGV)KERA [DGVbeta]
DECIPHERKERA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKERA 
Mutations
ICGC Data PortalKERA 
TCGA Data PortalKERA 
Broad Tumor PortalKERA
OASIS PortalKERA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKERA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKERA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KERA
DgiDB (Drug Gene Interaction Database)KERA
DoCM (Curated mutations)KERA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KERA (select a term)
intoGenKERA
Cancer3DKERA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM217300    603288   
Orphanet10736   
DisGeNETKERA
MedgenKERA
Genetic Testing Registry KERA
NextProtO60938 [Medical]
TSGene11081
GENETestsKERA
Target ValidationKERA
Huge Navigator KERA [HugePedia]
snp3D : Map Gene to Disease11081
BioCentury BCIQKERA
ClinGenKERA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11081
Chemical/Pharm GKB GenePA30088
Clinical trialKERA
Miscellaneous
canSAR (ICR)KERA (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKERA
EVEXKERA
GoPubMedKERA
iHOPKERA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:26:19 CET 2017

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