Fusion genes
(updated 2016) | KHSRP (19p13.3) / BHLHE41 (12p12.1) | KHSRP (19p13.3) / CD70 (19p13.3) | KHSRP (19p13.3) / CRTAP (3p22.3) |
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KHSRP (19p13.3) / FUBP1 (1p31.1) | KHSRP (19p13.3) / IGFBP5 (2q35) | KHSRP (19p13.3) / KHSRP (19p13.3) |
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SAFB2 (19p13.3) / KHSRP (19p13.3) | KHSRP 19p13.3 / CD70 19p13.3 | SAFB2 19p13.3 / KHSRP 19p13.3 |
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| Nomenclature |
|---|
| HGNC (Hugo) | KHSRP 6316 |
| Cards |
|---|
| Entrez_Gene (NCBI) | KHSRP 8570 KH-type splicing regulatory protein |
| Aliases | FBP2; FUBP2; KSRP |
| GeneCards (Weizmann) | KHSRP |
| Ensembl hg19 (Hinxton) | ENSG00000088247 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000088247 [Gene_View] chr19:6413108-6424811 [Contig_View] KHSRP [Vega] |
| ICGC DataPortal | ENSG00000088247 |
| TCGA cBioPortal | KHSRP |
| AceView (NCBI) | KHSRP |
| Genatlas (Paris) | KHSRP |
| WikiGenes | 8570 |
| SOURCE (Princeton) | KHSRP |
| Genetics Home Reference (NIH) | KHSRP |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | KHSRP - chr19:6413108-6424811 - 19p13.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | KHSRP - 19p13.3 [Description] (hg19-Feb_2009) |
| Ensembl | KHSRP - 19p13.3 [CytoView hg19] KHSRP - 19p13.3 [CytoView hg38] |
| Mapping of homologs : NCBI | KHSRP [Mapview hg19] KHSRP [Mapview hg38] |
| OMIM | 603445 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA976482 AB209662 AK300957 BC009473 BC085004 |
| RefSeq transcript (Entrez) | NM_003685 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | KHSRP |
| Cluster EST : Unigene | Hs.727344 [ NCBI ] |
| CGAP (NCI) | Hs.727344 |
| Alternative Splicing Gallery | ENSG00000088247 |
| Gene Expression | KHSRP [ NCBI-GEO ] KHSRP [ EBI - ARRAY_EXPRESS ]
KHSRP [ SEEK ] KHSRP [ MEM ] |
| Gene Expression Viewer (FireBrowse) | KHSRP [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevisible | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 8570 |
| GTEX Portal (Tissue expression) | KHSRP |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q92945 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q92945 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q92945 |
| Splice isoforms : SwissVar | Q92945 |
| PhosPhoSitePlus | Q92945 |
| Domaine pattern : Prosite (Expaxy) | KH_TYPE_1 (PS50084) |
| Domains : Interpro (EBI) | DUF1897 KH_dom KH_dom_type_1 |
| Domain families : Pfam (Sanger) | DUF1897 (PF09005) KH_1 (PF00013) |
| Domain families : Pfam (NCBI) | pfam09005 pfam00013 |
| Domain families : Smart (EMBL) | KH (SM00322) |
| Conserved Domain (NCBI) | KHSRP |
| DMDM Disease mutations | 8570 |
| Blocks (Seattle) | KHSRP |
| PDB (SRS) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| PDB (PDBSum) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| PDB (IMB) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| PDB (RSDB) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| Structural Biology KnowledgeBase | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| SCOP (Structural Classification of Proteins) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| CATH (Classification of proteins structures) | 2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T |
| Superfamily | Q92945 |
| Human Protein Atlas | ENSG00000088247 |
| Peptide Atlas | Q92945 |
| HPRD | 10350 |
| IPI | IPI00479786 IPI00855957 IPI00909344 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q92945 |
| IntAct (EBI) | Q92945 |
| FunCoup | ENSG00000088247 |
| BioGRID | KHSRP |
| STRING (EMBL) | KHSRP |
| ZODIAC | KHSRP |
| Ontologies - Pathways |
|---|
| QuickGO | Q92945 |
| Ontology : AmiGO | exosome (RNase complex) RNA splicing, via transesterification reactions DNA binding RNA binding protein binding nucleoplasm nucleoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated mRNA processing mRNA catabolic process RNA splicing cytoplasmic stress granule miRNA metabolic process membrane mRNA 3'-UTR AU-rich region binding regulation of mRNA stability regulation of mRNA stability negative regulation of nitric oxide biosynthetic process mRNA transport positive regulation of mRNA catabolic process 3'-UTR-mediated mRNA destabilization cellular response to cytokine stimulus regulation of miRNA metabolic process |
| Ontology : EGO-EBI | exosome (RNase complex) RNA splicing, via transesterification reactions DNA binding RNA binding protein binding nucleoplasm nucleoplasm cytosol transcription, DNA-templated regulation of transcription, DNA-templated mRNA processing mRNA catabolic process RNA splicing cytoplasmic stress granule miRNA metabolic process membrane mRNA 3'-UTR AU-rich region binding regulation of mRNA stability regulation of mRNA stability negative regulation of nitric oxide biosynthetic process mRNA transport positive regulation of mRNA catabolic process 3'-UTR-mediated mRNA destabilization cellular response to cytokine stimulus regulation of miRNA metabolic process |
| NDEx Network | KHSRP |
| Atlas of Cancer Signalling Network | KHSRP |
| Wikipedia pathways | KHSRP |
| Orthology - Evolution |
|---|
| OrthoDB | 8570 |
| GeneTree (enSembl) | ENSG00000088247 |
| Phylogenetic Trees/Animal Genes : TreeFam | KHSRP |
| HOVERGEN | Q92945 |
| HOGENOM | Q92945 |
| Homologs : HomoloGene | KHSRP |
| Homology/Alignments : Family Browser (UCSC) | KHSRP |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | KHSRP/CD70 [19p13.3/19p13.3] |
| Fusion : Mitelman | SAFB2/KHSRP [19p13.3/19p13.3] [t(19;19)(p13;p13)] |
| Fusion: TCGA | KHSRP 19p13.3 CD70 19p13.3 BRCA |
| Fusion: TCGA | SAFB2 19p13.3 KHSRP 19p13.3 PRAD |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | KHSRP [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | KHSRP |
| dbVar | KHSRP |
| ClinVar | KHSRP |
| 1000_Genomes | KHSRP |
| Exome Variant Server | KHSRP |
| ExAC (Exome Aggregation Consortium) | KHSRP (select the gene name) |
| Genetic variants : HAPMAP | 8570 |
| Genomic Variants (DGV) | KHSRP [DGVbeta] |
| DECIPHER | KHSRP [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | KHSRP |
| Mutations |
|---|
| ICGC Data Portal | KHSRP |
| TCGA Data Portal | KHSRP |
| Broad Tumor Portal | KHSRP |
| OASIS Portal | KHSRP [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | KHSRP [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | KHSRP |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search KHSRP |
| DgiDB (Drug Gene Interaction Database) | KHSRP |
| DoCM (Curated mutations) | KHSRP (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | KHSRP (select a term) |
| intoGen | KHSRP |
| Cancer3D | KHSRP(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 603445 |
| Orphanet | |
| Medgen | KHSRP |
| Genetic Testing Registry | KHSRP
|
| NextProt | Q92945 [Medical] |
| TSGene | 8570 |
| GENETests | KHSRP |
| Target Validation | KHSRP |
| Huge Navigator |
KHSRP [HugePedia] |
| snp3D : Map Gene to Disease | 8570 |
| BioCentury BCIQ | KHSRP |
| ClinGen | KHSRP |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 8570 |
| Chemical/Pharm GKB Gene | PA30097 |
| Clinical trial | KHSRP |
| Miscellaneous |
|---|
| canSAR (ICR) | KHSRP (select the gene name) |
| Probes |
|---|
| Litterature |
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| PubMed | 90 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | KHSRP |
| EVEX | KHSRP |
| GoPubMed | KHSRP |
| iHOP | KHSRP |
