Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KIAA1804 (mixed lineage kinase 4)

Identity

Other aliasMLK4
dJ862P8.3
HGNC (Hugo) -
LocusID (NCBI) 84451
Atlas_Id 64902
Location 1q42.2  [Link to chromosome band 1q42]
Location_base_pair Starts at 233463514 and ends at 233520894 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)-   -
Cards
Entrez_Gene (NCBI)KIAA1804  84451  mixed lineage kinase 4
AliasesMLK4; dJ862P8.3
GeneCards (Weizmann)KIAA1804
Ensembl hg19 (Hinxton)ENSG00000143674 [Gene_View]  chr1:233463514-233520894 [Contig_View]  KIAA1804 [Vega]
Ensembl hg38 (Hinxton)ENSG00000143674 [Gene_View]  chr1:233463514-233520894 [Contig_View]  KIAA1804 [Vega]
ICGC DataPortalENSG00000143674
TCGA cBioPortalKIAA1804
AceView (NCBI)KIAA1804
Genatlas (Paris)KIAA1804
WikiGenes84451
SOURCE (Princeton)KIAA1804
Genetics Home Reference (NIH)KIAA1804
Genomic and cartography
GoldenPath hg19 (UCSC)KIAA1804  -     chr1:233463514-233520894 +  1q42.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIAA1804  -     1q42.2   [Description]    (hg38-Dec_2013)
EnsemblKIAA1804 - 1q42.2 [CytoView hg19]  KIAA1804 - 1q42.2 [CytoView hg38]
Mapping of homologs : NCBIKIAA1804 [Mapview hg19]  KIAA1804 [Mapview hg38]
OMIM614793   
Gene and transcription
Genbank (Entrez)AB058707 AJ311797 AJ311798 AK309811 BC136648
RefSeq transcript (Entrez)NM_032435
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_167186 NW_004929294
Consensus coding sequences : CCDS (NCBI)KIAA1804
Cluster EST : UnigeneHs.547779 [ NCBI ]
CGAP (NCI)Hs.547779
Alternative Splicing GalleryENSG00000143674
Gene ExpressionKIAA1804 [ NCBI-GEO ]   KIAA1804 [ EBI - ARRAY_EXPRESS ]   KIAA1804 [ SEEK ]   KIAA1804 [ MEM ]
Gene Expression Viewer (FireBrowse)KIAA1804 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84451
GTEX Portal (Tissue expression)KIAA1804
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TCX8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TCX8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TCX8
Splice isoforms : SwissVarQ5TCX8
Catalytic activity : Enzyme2.7.11.25 [ Enzyme-Expasy ]   2.7.11.252.7.11.25 [ IntEnz-EBI ]   2.7.11.25 [ BRENDA ]   2.7.11.25 [ KEGG ]   
PhosPhoSitePlusQ5TCX8
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)    SH3 (PS50002)   
Domains : Interpro (EBI)Kinase-like_dom    MLK1/MLK2/MLK4    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser-Thr/Tyr_kinase_cat_dom    Ser/Thr_kinase_AS    SH3_domain    Tyr_kinase_cat_dom   
Domain families : Pfam (Sanger)Pkinase_Tyr (PF07714)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam07714    pfam14604   
Domain families : Smart (EMBL)SH3 (SM00326)  TyrKc (SM00219)  
Conserved Domain (NCBI)KIAA1804
DMDM Disease mutations84451
Blocks (Seattle)KIAA1804
SuperfamilyQ5TCX8
Human Protein AtlasENSG00000143674
Peptide AtlasQ5TCX8
HPRD10087
IPIIPI00142487   IPI00607875   IPI00607654   
Protein Interaction databases
DIP (DOE-UCLA)Q5TCX8
IntAct (EBI)Q5TCX8
FunCoupENSG00000143674
BioGRIDKIAA1804
STRING (EMBL)KIAA1804
ZODIACKIAA1804
Ontologies - Pathways
QuickGOQ5TCX8
Ontology : AmiGOactivation of MAPKK activity  MAP kinase kinase kinase activity  protein tyrosine kinase activity  ATP binding  cellular_component  intracellular  protein phosphorylation  activation of JUN kinase activity  peptidyl-tyrosine phosphorylation  protein homodimerization activity  protein autophosphorylation  
Ontology : EGO-EBIactivation of MAPKK activity  MAP kinase kinase kinase activity  protein tyrosine kinase activity  ATP binding  cellular_component  intracellular  protein phosphorylation  activation of JUN kinase activity  peptidyl-tyrosine phosphorylation  protein homodimerization activity  protein autophosphorylation  
NDEx NetworkKIAA1804
Atlas of Cancer Signalling NetworkKIAA1804
Wikipedia pathwaysKIAA1804
Orthology - Evolution
OrthoDB84451
GeneTree (enSembl)ENSG00000143674
Phylogenetic Trees/Animal Genes : TreeFam-
HOVERGENQ5TCX8
HOGENOMQ5TCX8
Homologs : HomoloGeneKIAA1804
Homology/Alignments : Family Browser (UCSC)KIAA1804
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIAA1804 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIAA1804
dbVarKIAA1804
ClinVarKIAA1804
1000_GenomesKIAA1804 
Exome Variant ServerKIAA1804
ExAC (Exome Aggregation Consortium)KIAA1804 (select the gene name)
Genetic variants : HAPMAP84451
Genomic Variants (DGV)KIAA1804 [DGVbeta]
DECIPHER (Syndromes)1:233463514-233520894  ENSG00000143674
CONAN: Copy Number AnalysisKIAA1804 
Mutations
ICGC Data Portal- 
TCGA Data Portal- 
Broad Tumor Portal-
OASIS Portal- [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIAA1804  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMD-
BioMutasearch KIAA1804
DgiDB (Drug Gene Interaction Database)KIAA1804
DoCM (Curated mutations)KIAA1804 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIAA1804 (select a term)
intoGenKIAA1804
Cancer3DKIAA1804(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM614793   
Orphanet
MedgenKIAA1804
Genetic Testing Registry KIAA1804
NextProtQ5TCX8 [Medical]
TSGene84451
GENETestsKIAA1804
Huge Navigator - [HugePedia]
snp3D : Map Gene to Disease84451
BioCentury BCIQKIAA1804
ClinGenKIAA1804
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84451
Clinical trialKIAA1804
Miscellaneous
canSAR (ICR)KIAA1804 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIAA1804
EVEXKIAA1804
GoPubMedKIAA1804
iHOPKIAA1804
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:09:49 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.