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KIDINS220 (kinase D-interacting substrate 220kDa)

Identity

Alias_nameskinase D-interacting substrate
Alias_symbol (synonym)ARMS
Other alias
HGNC (Hugo) KIDINS220
LocusID (NCBI) 57498
Atlas_Id 49984
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 8868987 and ends at 8977755 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KIDINS220 (2p25.1) / COL15A1 (9q22.33)KIDINS220 (2p25.1) / EYS (6q12)KIDINS220 (2p25.1) / FHAD1 (1p36.21)
KIDINS220 (2p25.1) / SND1 (7q32.1)KIDINS220 2p25.1 / EYS 6q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIDINS220   29508
Cards
Entrez_Gene (NCBI)KIDINS220  57498  kinase D-interacting substrate 220kDa
AliasesARMS
GeneCards (Weizmann)KIDINS220
Ensembl hg19 (Hinxton)ENSG00000134313 [Gene_View]  chr2:8868987-8977755 [Contig_View]  KIDINS220 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134313 [Gene_View]  chr2:8868987-8977755 [Contig_View]  KIDINS220 [Vega]
ICGC DataPortalENSG00000134313
TCGA cBioPortalKIDINS220
AceView (NCBI)KIDINS220
Genatlas (Paris)KIDINS220
WikiGenes57498
SOURCE (Princeton)KIDINS220
Genetics Home Reference (NIH)KIDINS220
Genomic and cartography
GoldenPath hg19 (UCSC)KIDINS220  -     chr2:8868987-8977755 -  2p25.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIDINS220  -     2p25.1   [Description]    (hg38-Dec_2013)
EnsemblKIDINS220 - 2p25.1 [CytoView hg19]  KIDINS220 - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBIKIDINS220 [Mapview hg19]  KIDINS220 [Mapview hg38]
OMIM615759   
Gene and transcription
Genbank (Entrez)AB033076 AB621829 AI088931 AK022873 AK023926
RefSeq transcript (Entrez)NM_020738
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005334 NW_004929298
Consensus coding sequences : CCDS (NCBI)KIDINS220
Cluster EST : UnigeneHs.9873 [ NCBI ]
CGAP (NCI)Hs.9873
Alternative Splicing GalleryENSG00000134313
Gene ExpressionKIDINS220 [ NCBI-GEO ]   KIDINS220 [ EBI - ARRAY_EXPRESS ]   KIDINS220 [ SEEK ]   KIDINS220 [ MEM ]
Gene Expression Viewer (FireBrowse)KIDINS220 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57498
GTEX Portal (Tissue expression)KIDINS220
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULH0
Splice isoforms : SwissVarQ9ULH0
PhosPhoSitePlusQ9ULH0
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom    KAP_P-loop    SAM/pointed   
Domain families : Pfam (Sanger)Ank_2 (PF12796)    KAP_NTPase (PF07693)   
Domain families : Pfam (NCBI)pfam12796    pfam07693   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)KIDINS220
DMDM Disease mutations57498
Blocks (Seattle)KIDINS220
SuperfamilyQ9ULH0
Human Protein AtlasENSG00000134313
Peptide AtlasQ9ULH0
HPRD17235
IPIIPI00885055   IPI00384909   IPI00183964   IPI00885052   IPI00884985   IPI00945293   IPI00947245   IPI00946906   IPI00945435   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULH0
IntAct (EBI)Q9ULH0
FunCoupENSG00000134313
BioGRIDKIDINS220
STRING (EMBL)KIDINS220
ZODIACKIDINS220
Ontologies - Pathways
QuickGOQ9ULH0
Ontology : AmiGOactivation of MAPKK activity  in utero embryonic development  late endosome  cytosol  positive regulation of neuron projection development  membrane  integral component of membrane  protein kinase regulator activity  PDZ domain binding  PDZ domain binding  nerve growth factor signaling pathway  nerve growth factor signaling pathway  protein complex  regulation of protein kinase activity  dendrite morphogenesis  cellular response to nerve growth factor stimulus  
Ontology : EGO-EBIactivation of MAPKK activity  in utero embryonic development  late endosome  cytosol  positive regulation of neuron projection development  membrane  integral component of membrane  protein kinase regulator activity  PDZ domain binding  PDZ domain binding  nerve growth factor signaling pathway  nerve growth factor signaling pathway  protein complex  regulation of protein kinase activity  dendrite morphogenesis  cellular response to nerve growth factor stimulus  
Pathways : KEGGNeurotrophin signaling pathway   
NDEx NetworkKIDINS220
Atlas of Cancer Signalling NetworkKIDINS220
Wikipedia pathwaysKIDINS220
Orthology - Evolution
OrthoDB57498
GeneTree (enSembl)ENSG00000134313
Phylogenetic Trees/Animal Genes : TreeFamKIDINS220
HOVERGENQ9ULH0
HOGENOMQ9ULH0
Homologs : HomoloGeneKIDINS220
Homology/Alignments : Family Browser (UCSC)KIDINS220
Gene fusions - Rearrangements
Fusion : MitelmanKIDINS220/EYS [2p25.1/6q12]  
Fusion: TCGAKIDINS220 2p25.1 EYS 6q12 BLCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIDINS220 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIDINS220
dbVarKIDINS220
ClinVarKIDINS220
1000_GenomesKIDINS220 
Exome Variant ServerKIDINS220
ExAC (Exome Aggregation Consortium)KIDINS220 (select the gene name)
Genetic variants : HAPMAP57498
Genomic Variants (DGV)KIDINS220 [DGVbeta]
DECIPHER (Syndromes)2:8868987-8977755  ENSG00000134313
CONAN: Copy Number AnalysisKIDINS220 
Mutations
ICGC Data PortalKIDINS220 
TCGA Data PortalKIDINS220 
Broad Tumor PortalKIDINS220
OASIS PortalKIDINS220 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIDINS220  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIDINS220
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIDINS220
DgiDB (Drug Gene Interaction Database)KIDINS220
DoCM (Curated mutations)KIDINS220 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIDINS220 (select a term)
intoGenKIDINS220
Cancer3DKIDINS220(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615759   
Orphanet
MedgenKIDINS220
Genetic Testing Registry KIDINS220
NextProtQ9ULH0 [Medical]
TSGene57498
GENETestsKIDINS220
Huge Navigator KIDINS220 [HugePedia]
snp3D : Map Gene to Disease57498
BioCentury BCIQKIDINS220
ClinGenKIDINS220
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57498
Chemical/Pharm GKB GenePA164721911
Clinical trialKIDINS220
Miscellaneous
canSAR (ICR)KIDINS220 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIDINS220
EVEXKIDINS220
GoPubMedKIDINS220
iHOPKIDINS220
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:06:08 CEST 2017

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