| Nomenclature |
|---|
| HGNC (Hugo) | KIF18A 29441 |
| Cards |
|---|
| Entrez_Gene (NCBI) | KIF18A kinesin family member 18A |
| Aliases | MS-KIF18A; PPP1R99 |
| GeneCards (Weizmann) | KIF18A |
| Ensembl hg19 (Hinxton) | ENSG00000121621 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000121621 [Gene_View] ENSG00000121621 [Sequence] chr11:28020619-28108156 [Contig_View] KIF18A [Vega] |
| ICGC DataPortal | ENSG00000121621 |
| TCGA cBioPortal | KIF18A |
| AceView (NCBI) | KIF18A |
| Genatlas (Paris) | KIF18A |
| SOURCE (Princeton) | KIF18A |
| Genetics Home Reference (NIH) | KIF18A |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | KIF18A - chr11:28020619-28108156 - 11p14.1 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | KIF18A - 11p14.1 [Description] (hg19-Feb_2009) |
| GoldenPath | KIF18A - 11p14.1 [CytoView hg19] KIF18A - 11p14.1 [CytoView hg38] |
| ImmunoBase | ENSG00000121621 |
| genome Data Viewer NCBI | KIF18A [Mapview hg19] |
| OMIM | 611271 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AB062483 AK093850 AK312576 AL136819 AW770226 |
| RefSeq transcript (Entrez) | NM_031217 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | KIF18A |
| Alternative Splicing Gallery | ENSG00000121621 |
| Gene Expression | KIF18A [ NCBI-GEO ] KIF18A [ EBI - ARRAY_EXPRESS ]
KIF18A [ SEEK ] KIF18A [ MEM ] |
| Gene Expression Viewer (FireBrowse) | KIF18A [ Firebrowse - Broad ] |
| Genevisible | Expression of KIF18A in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 81930 |
| GTEX Portal (Tissue expression) | KIF18A |
| Human Protein Atlas | ENSG00000121621-KIF18A [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q8NI77 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q8NI77 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q8NI77 |
| Splice isoforms : SwissVar | Q8NI77 |
| PhosPhoSitePlus | Q8NI77 |
| Domaine pattern : Prosite (Expaxy) | KINESIN_MOTOR_1 (PS00411) KINESIN_MOTOR_2 (PS50067) |
| Domains : Interpro (EBI) | Kinesin-like_fam Kinesin_motor_CS Kinesin_motor_dom Kinesin_motor_dom_sf P-loop_NTPase |
| Domain families : Pfam (Sanger) | Kinesin (PF00225) |
| Domain families : Pfam (NCBI) | pfam00225 |
| Domain families : Smart (EMBL) | KISc (SM00129) |
| Conserved Domain (NCBI) | KIF18A |
| Blocks (Seattle) | KIF18A |
| PDB (RSDB) | 3LRE 5OAM 5OCU 5OGC |
| PDB Europe | 3LRE 5OAM 5OCU 5OGC |
| PDB (PDBSum) | 3LRE 5OAM 5OCU 5OGC |
| PDB (IMB) | 3LRE 5OAM 5OCU 5OGC |
| Structural Biology KnowledgeBase | 3LRE 5OAM 5OCU 5OGC |
| SCOP (Structural Classification of Proteins) | 3LRE 5OAM 5OCU 5OGC |
| CATH (Classification of proteins structures) | 3LRE 5OAM 5OCU 5OGC |
| Superfamily | Q8NI77 |
| Human Protein Atlas [tissue] | ENSG00000121621-KIF18A [tissue] |
| Peptide Atlas | Q8NI77 |
| HPRD | 11177 |
| IPI | IPI00171768 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q8NI77 |
| IntAct (EBI) | Q8NI77 |
| BioGRID | KIF18A |
| STRING (EMBL) | KIF18A |
| ZODIAC | KIF18A |
| Ontologies - Pathways |
|---|
| QuickGO | Q8NI77 |
| Ontology : AmiGO | mitotic sister chromatid segregation kinetochore ruffle microtubule motor activity actin binding protein binding ATP binding nucleus nucleus cytoplasm microtubule organizing center kinetochore microtubule cytosol kinesin complex microtubule caveola retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum microtubule-based movement microtubule-based movement microtubule depolymerization microtubule depolymerization mitotic metaphase plate congression male meiotic nuclear division microtubule binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed ATP-dependent microtubule motor activity, plus-end-directed protein transport microtubule cytoskeleton ATPase activity antigen processing and presentation of exogenous peptide antigen via MHC class II microtubule plus-end binding mitotic spindle astral microtubule tubulin-dependent ATPase activity regulation of microtubule cytoskeleton organization cellular response to estradiol stimulus seminiferous tubule development mitotic spindle midzone |
| Ontology : EGO-EBI | mitotic sister chromatid segregation kinetochore ruffle microtubule motor activity actin binding protein binding ATP binding nucleus nucleus cytoplasm microtubule organizing center kinetochore microtubule cytosol kinesin complex microtubule caveola retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum microtubule-based movement microtubule-based movement microtubule depolymerization microtubule depolymerization mitotic metaphase plate congression male meiotic nuclear division microtubule binding microtubule binding ATP-dependent microtubule motor activity, plus-end-directed ATP-dependent microtubule motor activity, plus-end-directed protein transport microtubule cytoskeleton ATPase activity antigen processing and presentation of exogenous peptide antigen via MHC class II microtubule plus-end binding mitotic spindle astral microtubule tubulin-dependent ATPase activity regulation of microtubule cytoskeleton organization cellular response to estradiol stimulus seminiferous tubule development mitotic spindle midzone |
| NDEx Network | KIF18A |
| Atlas of Cancer Signalling Network | KIF18A |
| Wikipedia pathways | KIF18A |
| Orthology - Evolution |
|---|
| OrthoDB | 81930 |
| GeneTree (enSembl) | ENSG00000121621 |
| Phylogenetic Trees/Animal Genes : TreeFam | KIF18A |
| HOGENOM | Q8NI77 |
| Homologs : HomoloGene | KIF18A |
| Homology/Alignments : Family Browser (UCSC) | KIF18A |
| Gene fusions - Rearrangements |
|---|
| Fusion Cancer (Beijing) | KIF18A [11p14.1] - BLVRB [19q13.2] [FUSC001538] |
| Fusion : Quiver | KIF18A |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | KIF18A [hg38] |
| dbVar | KIF18A |
| ClinVar | KIF18A |
| Monarch | KIF18A |
| 1000_Genomes | KIF18A |
| Exome Variant Server | KIF18A |
| GNOMAD Browser | ENSG00000121621 |
| Varsome Browser | KIF18A |
| Genomic Variants (DGV) | KIF18A [DGVbeta] |
| DECIPHER | KIF18A [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | KIF18A |
| Mutations |
|---|
| ICGC Data Portal | KIF18A |
| TCGA Data Portal | KIF18A |
| Broad Tumor Portal | KIF18A |
| OASIS Portal | KIF18A [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | KIF18A [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | KIF18A |
| Mutations and Diseases : HGMD | KIF18A |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search KIF18A |
| DgiDB (Drug Gene Interaction Database) | KIF18A |
| DoCM (Curated mutations) | KIF18A (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | KIF18A (select a term) |
| intoGen | KIF18A |
| Cancer3D | KIF18A(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 611271 |
| Orphanet | |
| DisGeNET | KIF18A |
| Medgen | KIF18A |
| Genetic Testing Registry | KIF18A
|
| NextProt | Q8NI77 [Medical] |
| GENETests | KIF18A |
| Target Validation | KIF18A |
| Huge Navigator |
KIF18A [HugePedia] |
| ClinGen | KIF18A |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | KIF18A |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA134951326 |
| Pharos | Q8NI77 |
| Clinical trial | KIF18A |
| Miscellaneous |
|---|
| canSAR (ICR) | KIF18A (select the gene name) |
| Harmonizome | KIF18A |
| DataMed Index | KIF18A |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 62 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | KIF18A |
