Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIF18A (kinesin family member 18A)

Identity

Alias_namesregulatory subunit 99
Alias_symbol (synonym)DKFZP434G2226
PPP1R99
Other aliasMS-KIF18A
HGNC (Hugo) KIF18A
LocusID (NCBI) 81930
Atlas_Id 51714
Location 11p14.1  [Link to chromosome band 11p14]
Location_base_pair Starts at 28020616 and ends at 28108199 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIF18A (11p14.1) / BLVRB (19q13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF18A   29441
Cards
Entrez_Gene (NCBI)KIF18A  81930  kinesin family member 18A
AliasesMS-KIF18A; PPP1R99
GeneCards (Weizmann)KIF18A
Ensembl hg19 (Hinxton)ENSG00000121621 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000121621 [Gene_View]  chr11:28020616-28108199 [Contig_View]  KIF18A [Vega]
ICGC DataPortalENSG00000121621
TCGA cBioPortalKIF18A
AceView (NCBI)KIF18A
Genatlas (Paris)KIF18A
WikiGenes81930
SOURCE (Princeton)KIF18A
Genetics Home Reference (NIH)KIF18A
Genomic and cartography
GoldenPath hg38 (UCSC)KIF18A  -     chr11:28020616-28108199 -  11p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF18A  -     11p14.1   [Description]    (hg19-Feb_2009)
EnsemblKIF18A - 11p14.1 [CytoView hg19]  KIF18A - 11p14.1 [CytoView hg38]
Mapping of homologs : NCBIKIF18A [Mapview hg19]  KIF18A [Mapview hg38]
OMIM611271   
Gene and transcription
Genbank (Entrez)AB062483 AK093850 AK312576 AL136819 AM393105
RefSeq transcript (Entrez)NM_031217
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF18A
Cluster EST : UnigeneHs.301052 [ NCBI ]
CGAP (NCI)Hs.301052
Alternative Splicing GalleryENSG00000121621
Gene ExpressionKIF18A [ NCBI-GEO ]   KIF18A [ EBI - ARRAY_EXPRESS ]   KIF18A [ SEEK ]   KIF18A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF18A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81930
GTEX Portal (Tissue expression)KIF18A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NI77   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NI77  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NI77
Splice isoforms : SwissVarQ8NI77
PhosPhoSitePlusQ8NI77
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF18A
DMDM Disease mutations81930
Blocks (Seattle)KIF18A
PDB (SRS)3LRE   
PDB (PDBSum)3LRE   
PDB (IMB)3LRE   
PDB (RSDB)3LRE   
Structural Biology KnowledgeBase3LRE   
SCOP (Structural Classification of Proteins)3LRE   
CATH (Classification of proteins structures)3LRE   
SuperfamilyQ8NI77
Human Protein AtlasENSG00000121621
Peptide AtlasQ8NI77
HPRD11177
IPIIPI00171768   
Protein Interaction databases
DIP (DOE-UCLA)Q8NI77
IntAct (EBI)Q8NI77
FunCoupENSG00000121621
BioGRIDKIF18A
STRING (EMBL)KIF18A
ZODIACKIF18A
Ontologies - Pathways
QuickGOQ8NI77
Ontology : AmiGOkinetochore  ruffle  actin binding  protein binding  ATP binding  nucleus  cytoplasm  microtubule organizing center  kinetochore microtubule  cytosol  kinesin complex  caveola  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  microtubule depolymerization  sister chromatid cohesion  mitotic metaphase plate congression  male meiotic nuclear division  microtubule binding  ATP-dependent microtubule motor activity, plus-end-directed  protein transport  microtubule cytoskeleton  antigen processing and presentation of exogenous peptide antigen via MHC class II  ubiquitin binding  microtubule plus-end binding  tubulin-dependent ATPase activity  regulation of microtubule cytoskeleton organization  cellular response to estradiol stimulus  seminiferous tubule development  mitotic spindle midzone  
Ontology : EGO-EBIkinetochore  ruffle  actin binding  protein binding  ATP binding  nucleus  cytoplasm  microtubule organizing center  kinetochore microtubule  cytosol  kinesin complex  caveola  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  microtubule depolymerization  sister chromatid cohesion  mitotic metaphase plate congression  male meiotic nuclear division  microtubule binding  ATP-dependent microtubule motor activity, plus-end-directed  protein transport  microtubule cytoskeleton  antigen processing and presentation of exogenous peptide antigen via MHC class II  ubiquitin binding  microtubule plus-end binding  tubulin-dependent ATPase activity  regulation of microtubule cytoskeleton organization  cellular response to estradiol stimulus  seminiferous tubule development  mitotic spindle midzone  
NDEx NetworkKIF18A
Atlas of Cancer Signalling NetworkKIF18A
Wikipedia pathwaysKIF18A
Orthology - Evolution
OrthoDB81930
GeneTree (enSembl)ENSG00000121621
Phylogenetic Trees/Animal Genes : TreeFamKIF18A
HOVERGENQ8NI77
HOGENOMQ8NI77
Homologs : HomoloGeneKIF18A
Homology/Alignments : Family Browser (UCSC)KIF18A
Gene fusions - Rearrangements
Fusion Cancer (Beijing)KIF18A [11p14.1]  -  BLVRB [19q13.2]  [FUSC001538]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF18A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF18A
dbVarKIF18A
ClinVarKIF18A
1000_GenomesKIF18A 
Exome Variant ServerKIF18A
ExAC (Exome Aggregation Consortium)KIF18A (select the gene name)
Genetic variants : HAPMAP81930
Genomic Variants (DGV)KIF18A [DGVbeta]
DECIPHERKIF18A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF18A 
Mutations
ICGC Data PortalKIF18A 
TCGA Data PortalKIF18A 
Broad Tumor PortalKIF18A
OASIS PortalKIF18A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF18A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF18A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF18A
DgiDB (Drug Gene Interaction Database)KIF18A
DoCM (Curated mutations)KIF18A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF18A (select a term)
intoGenKIF18A
Cancer3DKIF18A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611271   
Orphanet
MedgenKIF18A
Genetic Testing Registry KIF18A
NextProtQ8NI77 [Medical]
TSGene81930
GENETestsKIF18A
Target ValidationKIF18A
Huge Navigator KIF18A [HugePedia]
snp3D : Map Gene to Disease81930
BioCentury BCIQKIF18A
ClinGenKIF18A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81930
Chemical/Pharm GKB GenePA134951326
Clinical trialKIF18A
Miscellaneous
canSAR (ICR)KIF18A (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF18A
EVEXKIF18A
GoPubMedKIF18A
iHOPKIF18A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:14:26 CEST 2017

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