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KIF20A (kinesin family member 20A)

Identity

Alias (NCBI)MKLP2
RAB6KIFL
RCM6
HGNC (Hugo) KIF20A
HGNC Previous nameRAB6KIFL
HGNC Previous nameRAB6 interacting, kinesin-like (rabkinesin6)
LocusID (NCBI) 10112
Atlas_Id 45523
Location 5q31.2  [Link to chromosome band 5q31]
Location_base_pair Starts at 138179112 and ends at 138187720 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KIF20A (5q31.2)::C3orf62 (3p21.31)KIF20A (5q31.2)::CDC23 (5q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)KIF20A   9787
Cards
Entrez_Gene (NCBI)KIF20A    kinesin family member 20A
AliasesMKLP2; RAB6KIFL; RCM6
GeneCards (Weizmann)KIF20A
Ensembl hg19 (Hinxton)ENSG00000112984 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112984 [Gene_View]  ENSG00000112984 [Sequence]  chr5:138179112-138187720 [Contig_View]  KIF20A [Vega]
ICGC DataPortalENSG00000112984
TCGA cBioPortalKIF20A
AceView (NCBI)KIF20A
Genatlas (Paris)KIF20A
SOURCE (Princeton)KIF20A
Genetics Home Reference (NIH)KIF20A
Genomic and cartography
GoldenPath hg38 (UCSC)KIF20A  -     chr5:138179112-138187720 +  5q31.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF20A  -     5q31.2   [Description]    (hg19-Feb_2009)
GoldenPathKIF20A - 5q31.2 [CytoView hg19]  KIF20A - 5q31.2 [CytoView hg38]
ImmunoBaseENSG00000112984
Genome Data Viewer NCBIKIF20A [Mapview hg19]  
OMIM605664   619433   
Gene and transcription
Genbank (Entrez)AF070672 AF153329 AK024804 AK025790 AK296879
RefSeq transcript (Entrez)NM_005733
Consensus coding sequences : CCDS (NCBI)KIF20A
Gene ExpressionKIF20A [ NCBI-GEO ]   KIF20A [ EBI - ARRAY_EXPRESS ]   KIF20A [ SEEK ]   KIF20A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF20A [ Firebrowse - Broad ]
GenevisibleExpression of KIF20A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10112
GTEX Portal (Tissue expression)KIF20A
Human Protein AtlasENSG00000112984-KIF20A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95235   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95235  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95235
PhosPhoSitePlusO95235
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)KIF20A    Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    Kinesin_motor_dom_sf    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF20A
PDB (RSDB)6YIP   
PDB Europe6YIP   
PDB (PDBSum)6YIP   
PDB (IMB)6YIP   
Structural Biology KnowledgeBase6YIP   
SCOP (Structural Classification of Proteins)6YIP   
CATH (Classification of proteins structures)6YIP   
SuperfamilyO95235
AlphaFold pdb e-kbO95235   
Human Protein Atlas [tissue]ENSG00000112984-KIF20A [tissue]
HPRD09292
Protein Interaction databases
DIP (DOE-UCLA)O95235
IntAct (EBI)O95235
BioGRIDKIF20A
STRING (EMBL)KIF20A
ZODIACKIF20A
Ontologies - Pathways
QuickGOO95235
Ontology : AmiGOmitotic cytokinesis  microtubule bundle formation  microtubule motor activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  spindle  kinesin complex  microtubule  microtubule-based movement  microtubule binding  protein transport  ATP hydrolysis activity  protein kinase binding  midbody  cleavage furrow  regulation of cytokinesis  intercellular bridge  midbody abscission  
Ontology : EGO-EBImitotic cytokinesis  microtubule bundle formation  microtubule motor activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  Golgi apparatus  spindle  kinesin complex  microtubule  microtubule-based movement  microtubule binding  protein transport  ATP hydrolysis activity  protein kinase binding  midbody  cleavage furrow  regulation of cytokinesis  intercellular bridge  midbody abscission  
NDEx NetworkKIF20A
Atlas of Cancer Signalling NetworkKIF20A
Wikipedia pathwaysKIF20A
Orthology - Evolution
OrthoDB10112
GeneTree (enSembl)ENSG00000112984
Phylogenetic Trees/Animal Genes : TreeFamKIF20A
Homologs : HomoloGeneKIF20A
Homology/Alignments : Family Browser (UCSC)KIF20A
Gene fusions - Rearrangements
Fusion : QuiverKIF20A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF20A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF20A
dbVarKIF20A
ClinVarKIF20A
MonarchKIF20A
1000_GenomesKIF20A 
Exome Variant ServerKIF20A
GNOMAD BrowserENSG00000112984
Varsome BrowserKIF20A
ACMGKIF20A variants
VarityO95235
Genomic Variants (DGV)KIF20A [DGVbeta]
DECIPHERKIF20A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF20A 
Mutations
ICGC Data PortalKIF20A 
TCGA Data PortalKIF20A 
Broad Tumor PortalKIF20A
OASIS PortalKIF20A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF20A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKIF20A
Mutations and Diseases : HGMDKIF20A
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaKIF20A
DgiDB (Drug Gene Interaction Database)KIF20A
DoCM (Curated mutations)KIF20A
CIViC (Clinical Interpretations of Variants in Cancer)KIF20A
Cancer3DKIF20A
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605664    619433   
Orphanet11069   
DisGeNETKIF20A
MedgenKIF20A
Genetic Testing Registry KIF20A
NextProtO95235 [Medical]
GENETestsKIF20A
Target ValidationKIF20A
Huge Navigator KIF20A [HugePedia]
ClinGenKIF20A
Clinical trials, drugs, therapy
MyCancerGenomeKIF20A
Protein Interactions : CTDKIF20A
Pharm GKB GenePA34149
PharosO95235
Clinical trialKIF20A
Miscellaneous
canSAR (ICR)KIF20A
HarmonizomeKIF20A
ARCHS4KIF20A
DataMed IndexKIF20A
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKIF20A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:39:46 CET 2022

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