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KIF20B (kinesin family member 20B)

Identity

Alias_namesMPHOSPH1
M-phase phosphoprotein 1
Alias_symbol (synonym)MPP1
KRMP1
CT90
Other aliasMPP-1
HGNC (Hugo) KIF20B
LocusID (NCBI) 9585
Atlas_Id 56542
Location 10q23.31  [Link to chromosome band 10q23]
Location_base_pair Starts at 91461347 and ends at 91534700 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CRIP2 (14q32.33) / KIF20B (10q23.31)GBE1 (3p12.2) / KIF20B (10q23.31)INPP5A (10q26.3) / KIF20B (10q23.31)
KIF20B (10q23.31) / GBE1 (3p12.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF20B   7212
Cards
Entrez_Gene (NCBI)KIF20B  9585  kinesin family member 20B
AliasesCT90; KRMP1; MPHOSPH1; MPP-1; 
MPP1
GeneCards (Weizmann)KIF20B
Ensembl hg19 (Hinxton)ENSG00000138182 [Gene_View]  chr10:91461347-91534700 [Contig_View]  KIF20B [Vega]
Ensembl hg38 (Hinxton)ENSG00000138182 [Gene_View]  chr10:91461347-91534700 [Contig_View]  KIF20B [Vega]
ICGC DataPortalENSG00000138182
TCGA cBioPortalKIF20B
AceView (NCBI)KIF20B
Genatlas (Paris)KIF20B
WikiGenes9585
SOURCE (Princeton)KIF20B
Genetics Home Reference (NIH)KIF20B
Genomic and cartography
GoldenPath hg19 (UCSC)KIF20B  -     chr10:91461347-91534700 +  10q23.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIF20B  -     10q23.31   [Description]    (hg38-Dec_2013)
EnsemblKIF20B - 10q23.31 [CytoView hg19]  KIF20B - 10q23.31 [CytoView hg38]
Mapping of homologs : NCBIKIF20B [Mapview hg19]  KIF20B [Mapview hg38]
OMIM605498   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001284259 NM_016195
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF20B
Cluster EST : UnigeneHs.240 [ NCBI ]
CGAP (NCI)Hs.240
Alternative Splicing GalleryENSG00000138182
Gene ExpressionKIF20B [ NCBI-GEO ]   KIF20B [ EBI - ARRAY_EXPRESS ]   KIF20B [ SEEK ]   KIF20B [ MEM ]
Gene Expression Viewer (FireBrowse)KIF20B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9585
GTEX Portal (Tissue expression)KIF20B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96Q89   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96Q89  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96Q89
Splice isoforms : SwissVarQ96Q89
PhosPhoSitePlusQ96Q89
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)KIF20B    Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF20B
DMDM Disease mutations9585
Blocks (Seattle)KIF20B
SuperfamilyQ96Q89
Human Protein AtlasENSG00000138182
Peptide AtlasQ96Q89
HPRD09268
IPIIPI00827503   IPI00412862   IPI00644494   IPI00827980   IPI00044751   IPI00643326   
Protein Interaction databases
DIP (DOE-UCLA)Q96Q89
IntAct (EBI)Q96Q89
FunCoupENSG00000138182
BioGRIDKIF20B
STRING (EMBL)KIF20B
ZODIACKIF20B
Ontologies - Pathways
QuickGOQ96Q89
Ontology : AmiGOneural tube closure  protein binding  ATP binding  nucleus  nucleoplasm  nucleolus  cytoplasm  centrosome  kinesin complex  microtubule  microtubule-based movement  cell cycle arrest  mitotic nuclear division  regulation of mitotic nuclear division  microtubule binding  positive regulation of cell proliferation  positive regulation of cell proliferation  ATP-dependent microtubule motor activity, plus-end-directed  ATPase activity  axon  growth cone  midbody  midbody  positive regulation of cytokinesis  protein localization to microtubule  protein homodimerization activity  perinuclear region of cytoplasm  neuron projection morphogenesis  WW domain binding  spindle midzone  cell division  contractile ring  positive regulation of intracellular protein transport  mitotic spindle pole  positive regulation of mitotic cytokinetic process  mitotic spindle midzone  regulation of establishment of cell polarity  positive regulation of neuron migration  
Ontology : EGO-EBIneural tube closure  protein binding  ATP binding  nucleus  nucleoplasm  nucleolus  cytoplasm  centrosome  kinesin complex  microtubule  microtubule-based movement  cell cycle arrest  mitotic nuclear division  regulation of mitotic nuclear division  microtubule binding  positive regulation of cell proliferation  positive regulation of cell proliferation  ATP-dependent microtubule motor activity, plus-end-directed  ATPase activity  axon  growth cone  midbody  midbody  positive regulation of cytokinesis  protein localization to microtubule  protein homodimerization activity  perinuclear region of cytoplasm  neuron projection morphogenesis  WW domain binding  spindle midzone  cell division  contractile ring  positive regulation of intracellular protein transport  mitotic spindle pole  positive regulation of mitotic cytokinetic process  mitotic spindle midzone  regulation of establishment of cell polarity  positive regulation of neuron migration  
NDEx NetworkKIF20B
Atlas of Cancer Signalling NetworkKIF20B
Wikipedia pathwaysKIF20B
Orthology - Evolution
OrthoDB9585
GeneTree (enSembl)ENSG00000138182
Phylogenetic Trees/Animal Genes : TreeFamKIF20B
HOVERGENQ96Q89
HOGENOMQ96Q89
Homologs : HomoloGeneKIF20B
Homology/Alignments : Family Browser (UCSC)KIF20B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF20B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF20B
dbVarKIF20B
ClinVarKIF20B
1000_GenomesKIF20B 
Exome Variant ServerKIF20B
ExAC (Exome Aggregation Consortium)KIF20B (select the gene name)
Genetic variants : HAPMAP9585
Genomic Variants (DGV)KIF20B [DGVbeta]
DECIPHER (Syndromes)10:91461347-91534700  ENSG00000138182
CONAN: Copy Number AnalysisKIF20B 
Mutations
ICGC Data PortalKIF20B 
TCGA Data PortalKIF20B 
Broad Tumor PortalKIF20B
OASIS PortalKIF20B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF20B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF20B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF20B
DgiDB (Drug Gene Interaction Database)KIF20B
DoCM (Curated mutations)KIF20B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF20B (select a term)
intoGenKIF20B
Cancer3DKIF20B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605498   
Orphanet
MedgenKIF20B
Genetic Testing Registry KIF20B
NextProtQ96Q89 [Medical]
TSGene9585
GENETestsKIF20B
Huge Navigator KIF20B [HugePedia]
snp3D : Map Gene to Disease9585
BioCentury BCIQKIF20B
ClinGenKIF20B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9585
Chemical/Pharm GKB GenePA162393285
Clinical trialKIF20B
Miscellaneous
canSAR (ICR)KIF20B (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF20B
EVEXKIF20B
GoPubMedKIF20B
iHOPKIF20B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:11:52 CET 2017

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