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KIF21A (kinesin family member 21A)

Identity

Alias_namesFEOM1
fibrosis of the extraocular muscles, congenital, 1
Alias_symbol (synonym)FLJ20052
Other aliasCFEOM1
FEOM3A
HGNC (Hugo) KIF21A
LocusID (NCBI) 55605
Atlas_Id 64919
Location 12q12  [Link to chromosome band 12q12]
Location_base_pair Starts at 39293228 and ends at 39443390 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KIF21A (12q12) / CADPS (3p14.2)KIF21A (12q12) / LMF1 (16p13.3)KIF21A (12q12) / PAIP2B (2p13.3)
KIF21A (12q12) / SLC2A13 (12q12)KIF21A (12q12) / TMTC2 (12q21.31)KIF21A (12q12) / TSPAN8 (12q21.1)
PIGK (1p31.1) / KIF21A (12q12)KIF21A TSPAN8KIF21A LMF1
KIF21A TMTC2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF21A   19349
Cards
Entrez_Gene (NCBI)KIF21A  55605  kinesin family member 21A
AliasesCFEOM1; FEOM1; FEOM3A
GeneCards (Weizmann)KIF21A
Ensembl hg19 (Hinxton)ENSG00000139116 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139116 [Gene_View]  chr12:39293228-39443390 [Contig_View]  KIF21A [Vega]
ICGC DataPortalENSG00000139116
TCGA cBioPortalKIF21A
AceView (NCBI)KIF21A
Genatlas (Paris)KIF21A
WikiGenes55605
SOURCE (Princeton)KIF21A
Genetics Home Reference (NIH)KIF21A
Genomic and cartography
GoldenPath hg38 (UCSC)KIF21A  -     chr12:39293228-39443390 -  12q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF21A  -     12q12   [Description]    (hg19-Feb_2009)
EnsemblKIF21A - 12q12 [CytoView hg19]  KIF21A - 12q12 [CytoView hg38]
Mapping of homologs : NCBIKIF21A [Mapview hg19]  KIF21A [Mapview hg38]
OMIM135700   608283   
Gene and transcription
Genbank (Entrez)AB051495 AB290166 AF155117 AF450487 AK000059
RefSeq transcript (Entrez)NM_001173463 NM_001173464 NM_001173465 NM_017641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF21A
Cluster EST : UnigeneHs.374201 [ NCBI ]
CGAP (NCI)Hs.374201
Alternative Splicing GalleryENSG00000139116
Gene ExpressionKIF21A [ NCBI-GEO ]   KIF21A [ EBI - ARRAY_EXPRESS ]   KIF21A [ SEEK ]   KIF21A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF21A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55605
GTEX Portal (Tissue expression)KIF21A
Human Protein AtlasENSG00000139116-KIF21A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z4S6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z4S6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z4S6
Splice isoforms : SwissVarQ7Z4S6
PhosPhoSitePlusQ7Z4S6
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)    WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase    Prefoldin    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)Kinesin (PF00225)    WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00225    pfam00400   
Domain families : Smart (EMBL)KISc (SM00129)  WD40 (SM00320)  
Conserved Domain (NCBI)KIF21A
DMDM Disease mutations55605
Blocks (Seattle)KIF21A
PDB (SRS)5D3A   
PDB (PDBSum)5D3A   
PDB (IMB)5D3A   
PDB (RSDB)5D3A   
Structural Biology KnowledgeBase5D3A   
SCOP (Structural Classification of Proteins)5D3A   
CATH (Classification of proteins structures)5D3A   
SuperfamilyQ7Z4S6
Human Protein Atlas [tissue]ENSG00000139116-KIF21A [tissue]
Peptide AtlasQ7Z4S6
HPRD10506
IPIIPI00425404   IPI00425405   IPI00425407   IPI00425409   IPI01013864   IPI01024856   IPI01013445   IPI01022980   IPI01022696   IPI01022827   IPI01022315   IPI00956238   IPI01013038   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z4S6
IntAct (EBI)Q7Z4S6
FunCoupENSG00000139116
BioGRIDKIF21A
STRING (EMBL)KIF21A
ZODIACKIF21A
Ontologies - Pathways
QuickGOQ7Z4S6
Ontology : AmiGOmicrotubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  microtubule-based movement  microtubule binding  ATPase activity  
Ontology : EGO-EBImicrotubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  microtubule-based movement  microtubule binding  ATPase activity  
NDEx NetworkKIF21A
Atlas of Cancer Signalling NetworkKIF21A
Wikipedia pathwaysKIF21A
Orthology - Evolution
OrthoDB55605
GeneTree (enSembl)ENSG00000139116
Phylogenetic Trees/Animal Genes : TreeFamKIF21A
HOVERGENQ7Z4S6
HOGENOMQ7Z4S6
Homologs : HomoloGeneKIF21A
Homology/Alignments : Family Browser (UCSC)KIF21A
Gene fusions - Rearrangements
Fusion: TCGA_MDACCKIF21A TSPAN8
Fusion: TCGA_MDACCKIF21A LMF1
Fusion: TCGA_MDACCKIF21A TMTC2
Tumor Fusion PortalKIF21A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF21A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF21A
dbVarKIF21A
ClinVarKIF21A
1000_GenomesKIF21A 
Exome Variant ServerKIF21A
ExAC (Exome Aggregation Consortium)ENSG00000139116
GNOMAD BrowserENSG00000139116
Genetic variants : HAPMAP55605
Genomic Variants (DGV)KIF21A [DGVbeta]
DECIPHERKIF21A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF21A 
Mutations
ICGC Data PortalKIF21A 
TCGA Data PortalKIF21A 
Broad Tumor PortalKIF21A
OASIS PortalKIF21A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF21A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF21A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF21A
DgiDB (Drug Gene Interaction Database)KIF21A
DoCM (Curated mutations)KIF21A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF21A (select a term)
intoGenKIF21A
Cancer3DKIF21A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM135700    608283   
Orphanet10586   
DisGeNETKIF21A
MedgenKIF21A
Genetic Testing Registry KIF21A
NextProtQ7Z4S6 [Medical]
TSGene55605
GENETestsKIF21A
Target ValidationKIF21A
Huge Navigator KIF21A [HugePedia]
snp3D : Map Gene to Disease55605
BioCentury BCIQKIF21A
ClinGenKIF21A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55605
Chemical/Pharm GKB GenePA134882934
Clinical trialKIF21A
Miscellaneous
canSAR (ICR)KIF21A (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF21A
EVEXKIF21A
GoPubMedKIF21A
iHOPKIF21A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:26:20 CET 2017

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