Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIF22 (kinesin family member 22)

Identity

Alias_namesKNSL4
kinesin-like 4
Alias_symbol (synonym)Kid
OBP-1
OBP-2
Other aliasA-328A3.2
KID
OBP
SEMDJL2
HGNC (Hugo) KIF22
LocusID (NCBI) 3835
Atlas_Id 53339
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 29802034 and ends at 29816706 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MICALL2 (7p22.3) / KIF22 (16p11.2)MVP (16p11.2) / KIF22 (16p11.2)PHLPP2 (16q22.2) / KIF22 (16p11.2)
MVP 16p11.2 / KIF22 16p11.2PHLPP2 16q22.2 / KIF22 16p11.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF22   6391
Cards
Entrez_Gene (NCBI)KIF22  3835  kinesin family member 22
AliasesA-328A3.2; KID; KNSL4; OBP; 
OBP-1; OBP-2; SEMDJL2
GeneCards (Weizmann)KIF22
Ensembl hg19 (Hinxton)ENSG00000079616 [Gene_View]  chr16:29802034-29816706 [Contig_View]  KIF22 [Vega]
Ensembl hg38 (Hinxton)ENSG00000079616 [Gene_View]  chr16:29802034-29816706 [Contig_View]  KIF22 [Vega]
ICGC DataPortalENSG00000079616
TCGA cBioPortalKIF22
AceView (NCBI)KIF22
Genatlas (Paris)KIF22
WikiGenes3835
SOURCE (Princeton)KIF22
Genetics Home Reference (NIH)KIF22
Genomic and cartography
GoldenPath hg19 (UCSC)KIF22  -     chr16:29802034-29816706 +  16p11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIF22  -     16p11.2   [Description]    (hg38-Dec_2013)
EnsemblKIF22 - 16p11.2 [CytoView hg19]  KIF22 - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBIKIF22 [Mapview hg19]  KIF22 [Mapview hg38]
OMIM603213   603546   
Gene and transcription
Genbank (Entrez)AB017430 AK223431 AK294380 AK297893 AK312234
RefSeq transcript (Entrez)NM_001256269 NM_001256270 NM_007317
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_032055 NT_187260 NW_004929400
Consensus coding sequences : CCDS (NCBI)KIF22
Cluster EST : UnigeneHs.612151 [ NCBI ]
CGAP (NCI)Hs.612151
Alternative Splicing GalleryENSG00000079616
Gene ExpressionKIF22 [ NCBI-GEO ]   KIF22 [ EBI - ARRAY_EXPRESS ]   KIF22 [ SEEK ]   KIF22 [ MEM ]
Gene Expression Viewer (FireBrowse)KIF22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3835
GTEX Portal (Tissue expression)KIF22
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14807   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14807  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14807
Splice isoforms : SwissVarQ14807
PhosPhoSitePlusQ14807
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Hlx-hairpin-Hlx_DNA-bd_motif    KIF22    Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase    RuvA_2-like   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)HhH1 (SM00278)  KISc (SM00129)  
Conserved Domain (NCBI)KIF22
DMDM Disease mutations3835
Blocks (Seattle)KIF22
PDB (SRS)2EDU    3BFN   
PDB (PDBSum)2EDU    3BFN   
PDB (IMB)2EDU    3BFN   
PDB (RSDB)2EDU    3BFN   
Structural Biology KnowledgeBase2EDU    3BFN   
SCOP (Structural Classification of Proteins)2EDU    3BFN   
CATH (Classification of proteins structures)2EDU    3BFN   
SuperfamilyQ14807
Human Protein AtlasENSG00000079616
Peptide AtlasQ14807
HPRD04445
IPIIPI00000769   IPI00909938   IPI01015810   IPI00453005   
Protein Interaction databases
DIP (DOE-UCLA)Q14807
IntAct (EBI)Q14807
FunCoupENSG00000079616
BioGRIDKIF22
STRING (EMBL)KIF22
ZODIACKIF22
Ontologies - Pathways
QuickGOQ14807
Ontology : AmiGOkinetochore  chromatin  DNA binding  microtubule motor activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  kinesin complex  microtubule  focal adhesion  DNA repair  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  sister chromatid cohesion  mitotic nuclear division  mitotic metaphase plate congression  microtubule binding  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  metaphase plate congression  mitotic spindle  
Ontology : EGO-EBIkinetochore  chromatin  DNA binding  microtubule motor activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  kinesin complex  microtubule  focal adhesion  DNA repair  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  sister chromatid cohesion  mitotic nuclear division  mitotic metaphase plate congression  microtubule binding  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  metaphase plate congression  mitotic spindle  
NDEx NetworkKIF22
Atlas of Cancer Signalling NetworkKIF22
Wikipedia pathwaysKIF22
Orthology - Evolution
OrthoDB3835
GeneTree (enSembl)ENSG00000079616
Phylogenetic Trees/Animal Genes : TreeFamKIF22
HOVERGENQ14807
HOGENOMQ14807
Homologs : HomoloGeneKIF22
Homology/Alignments : Family Browser (UCSC)KIF22
Gene fusions - Rearrangements
Fusion : MitelmanMVP/KIF22 [16p11.2/16p11.2]  [t(16;16)(p11;p11)]  
Fusion : MitelmanPHLPP2/KIF22 [16q22.2/16p11.2]  [t(16;16)(p11;q22)]  
Fusion: TCGAMVP 16p11.2 KIF22 16p11.2 BRCA
Fusion: TCGAPHLPP2 16q22.2 KIF22 16p11.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF22
dbVarKIF22
ClinVarKIF22
1000_GenomesKIF22 
Exome Variant ServerKIF22
ExAC (Exome Aggregation Consortium)KIF22 (select the gene name)
Genetic variants : HAPMAP3835
Genomic Variants (DGV)KIF22 [DGVbeta]
DECIPHER (Syndromes)16:29802034-29816706  ENSG00000079616
CONAN: Copy Number AnalysisKIF22 
Mutations
ICGC Data PortalKIF22 
TCGA Data PortalKIF22 
Broad Tumor PortalKIF22
OASIS PortalKIF22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch KIF22
DgiDB (Drug Gene Interaction Database)KIF22
DoCM (Curated mutations)KIF22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF22 (select a term)
intoGenKIF22
Cancer3DKIF22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603213    603546   
Orphanet12291   
MedgenKIF22
Genetic Testing Registry KIF22
NextProtQ14807 [Medical]
TSGene3835
GENETestsKIF22
Huge Navigator KIF22 [HugePedia]
snp3D : Map Gene to Disease3835
BioCentury BCIQKIF22
ClinGenKIF22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3835
Chemical/Pharm GKB GenePA30180
Clinical trialKIF22
Miscellaneous
canSAR (ICR)KIF22 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF22
EVEXKIF22
GoPubMedKIF22
iHOPKIF22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:06:10 CEST 2017

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