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KIF2A (kinesin family member 2A)

Identity

Alias_namesKIF2
kinesin heavy chain member 2
Alias_symbol (synonym)HK2
Other aliasCDCBM3
HGNC (Hugo) KIF2A
LocusID (NCBI) 3796
Atlas_Id 54839
Location 5q12.1  [Link to chromosome band 5q12]
Location_base_pair Starts at 62306162 and ends at 62387184 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KIF2A (5q12.1) / ADAMTS19 (5q23.3)KIF2A 5q12.1 / ADAMTS19 5q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF2A   6318
Cards
Entrez_Gene (NCBI)KIF2A  3796  kinesin family member 2A
AliasesCDCBM3; HK2; KIF2
GeneCards (Weizmann)KIF2A
Ensembl hg19 (Hinxton)ENSG00000068796 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000068796 [Gene_View]  chr5:62306162-62387184 [Contig_View]  KIF2A [Vega]
ICGC DataPortalENSG00000068796
TCGA cBioPortalKIF2A
AceView (NCBI)KIF2A
Genatlas (Paris)KIF2A
WikiGenes3796
SOURCE (Princeton)KIF2A
Genetics Home Reference (NIH)KIF2A
Genomic and cartography
GoldenPath hg38 (UCSC)KIF2A  -     chr5:62306162-62387184 +  5q12.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF2A  -     5q12.1   [Description]    (hg19-Feb_2009)
EnsemblKIF2A - 5q12.1 [CytoView hg19]  KIF2A - 5q12.1 [CytoView hg38]
Mapping of homologs : NCBIKIF2A [Mapview hg19]  KIF2A [Mapview hg38]
OMIM602591   615411   
Gene and transcription
Genbank (Entrez)AI652174 AK297347 AK302270 AK307880 AK315866
RefSeq transcript (Entrez)NM_001098511 NM_001243952 NM_001243953 NM_004520
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF2A
Cluster EST : UnigeneHs.558351 [ NCBI ]
CGAP (NCI)Hs.558351
Alternative Splicing GalleryENSG00000068796
Gene ExpressionKIF2A [ NCBI-GEO ]   KIF2A [ EBI - ARRAY_EXPRESS ]   KIF2A [ SEEK ]   KIF2A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3796
GTEX Portal (Tissue expression)KIF2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00139   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00139  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00139
Splice isoforms : SwissVarO00139
PhosPhoSitePlusO00139
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF2A
DMDM Disease mutations3796
Blocks (Seattle)KIF2A
PDB (SRS)2GRY   
PDB (PDBSum)2GRY   
PDB (IMB)2GRY   
PDB (RSDB)2GRY   
Structural Biology KnowledgeBase2GRY   
SCOP (Structural Classification of Proteins)2GRY   
CATH (Classification of proteins structures)2GRY   
SuperfamilyO00139
Human Protein AtlasENSG00000068796
Peptide AtlasO00139
HPRD03996
IPIIPI00867529   IPI00867746   IPI00848334   IPI00010368   IPI00966835   IPI00967632   IPI00967890   
Protein Interaction databases
DIP (DOE-UCLA)O00139
IntAct (EBI)O00139
FunCoupENSG00000068796
BioGRIDKIF2A
STRING (EMBL)KIF2A
ZODIACKIF2A
Ontologies - Pathways
QuickGOO00139
Ontology : AmiGOspindle pole  motor activity  microtubule motor activity  protein binding  ATP binding  nucleus  nucleolus  centrosome  cytosol  kinesin complex  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  mitotic spindle organization  sister chromatid cohesion  nervous system development  microtubule binding  membrane  nuclear body  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  cell differentiation  cell division  mitotic spindle assembly  sperm principal piece  
Ontology : EGO-EBIspindle pole  motor activity  microtubule motor activity  protein binding  ATP binding  nucleus  nucleolus  centrosome  cytosol  kinesin complex  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  microtubule-based movement  mitotic spindle organization  sister chromatid cohesion  nervous system development  microtubule binding  membrane  nuclear body  ATPase activity  antigen processing and presentation of exogenous peptide antigen via MHC class II  cell differentiation  cell division  mitotic spindle assembly  sperm principal piece  
NDEx NetworkKIF2A
Atlas of Cancer Signalling NetworkKIF2A
Wikipedia pathwaysKIF2A
Orthology - Evolution
OrthoDB3796
GeneTree (enSembl)ENSG00000068796
Phylogenetic Trees/Animal Genes : TreeFamKIF2A
HOVERGENO00139
HOGENOMO00139
Homologs : HomoloGeneKIF2A
Homology/Alignments : Family Browser (UCSC)KIF2A
Gene fusions - Rearrangements
Fusion : MitelmanKIF2A/ADAMTS19 [5q12.1/5q23.3]  
Fusion: TCGAKIF2A 5q12.1 ADAMTS19 5q23.3 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF2A
dbVarKIF2A
ClinVarKIF2A
1000_GenomesKIF2A 
Exome Variant ServerKIF2A
ExAC (Exome Aggregation Consortium)KIF2A (select the gene name)
Genetic variants : HAPMAP3796
Genomic Variants (DGV)KIF2A [DGVbeta]
DECIPHERKIF2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF2A 
Mutations
ICGC Data PortalKIF2A 
TCGA Data PortalKIF2A 
Broad Tumor PortalKIF2A
OASIS PortalKIF2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF2A
DgiDB (Drug Gene Interaction Database)KIF2A
DoCM (Curated mutations)KIF2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF2A (select a term)
intoGenKIF2A
Cancer3DKIF2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602591    615411   
Orphanet
MedgenKIF2A
Genetic Testing Registry KIF2A
NextProtO00139 [Medical]
TSGene3796
GENETestsKIF2A
Target ValidationKIF2A
Huge Navigator KIF2A [HugePedia]
snp3D : Map Gene to Disease3796
BioCentury BCIQKIF2A
ClinGenKIF2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3796
Chemical/Pharm GKB GenePA162393356
Clinical trialKIF2A
Miscellaneous
canSAR (ICR)KIF2A (select the gene name)
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF2A
EVEXKIF2A
GoPubMedKIF2A
iHOPKIF2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:39:36 CEST 2017

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