Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KIF3B (kinesin family member 3B)

Identity

Alias_symbol (synonym)KIAA0359
FLA8
KLP-11
Other aliasHH0048
HGNC (Hugo) KIF3B
LocusID (NCBI) 9371
Atlas_Id 53015
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 32277651 and ends at 32335008 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IGDCC3 (15q22.31) / KIF3B (20q11.21)KIF3B (20q11.21) / KIF3B (20q11.21)KIF3B (20q11.21) / NINL (20p11.21)
KIF3B (20q11.21) / SMC2 (9q31.1)PAX5 (9p13.2) / KIF3B (20q11.21)SSR3 (3q25.31) / KIF3B (20q11.21)
KIF3B 20q11.21 / NINL 20p11.21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF3B   6320
Cards
Entrez_Gene (NCBI)KIF3B  9371  kinesin family member 3B
AliasesFLA8; HH0048; KLP-11
GeneCards (Weizmann)KIF3B
Ensembl hg19 (Hinxton)ENSG00000101350 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101350 [Gene_View]  chr20:32277651-32335008 [Contig_View]  KIF3B [Vega]
ICGC DataPortalENSG00000101350
TCGA cBioPortalKIF3B
AceView (NCBI)KIF3B
Genatlas (Paris)KIF3B
WikiGenes9371
SOURCE (Princeton)KIF3B
Genetics Home Reference (NIH)KIF3B
Genomic and cartography
GoldenPath hg38 (UCSC)KIF3B  -     chr20:32277651-32335008 +  20q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF3B  -     20q11.21   [Description]    (hg19-Feb_2009)
EnsemblKIF3B - 20q11.21 [CytoView hg19]  KIF3B - 20q11.21 [CytoView hg38]
Mapping of homologs : NCBIKIF3B [Mapview hg19]  KIF3B [Mapview hg38]
OMIM603754   
Gene and transcription
Genbank (Entrez)AB002357 AK098431 AK299877 AK302403 AL353976
RefSeq transcript (Entrez)NM_004798
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF3B
Cluster EST : UnigeneHs.369670 [ NCBI ]
CGAP (NCI)Hs.369670
Alternative Splicing GalleryENSG00000101350
Gene ExpressionKIF3B [ NCBI-GEO ]   KIF3B [ EBI - ARRAY_EXPRESS ]   KIF3B [ SEEK ]   KIF3B [ MEM ]
Gene Expression Viewer (FireBrowse)KIF3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9371
GTEX Portal (Tissue expression)KIF3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15066   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15066  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15066
Splice isoforms : SwissVarO15066
PhosPhoSitePlusO15066
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF3B
DMDM Disease mutations9371
Blocks (Seattle)KIF3B
PDB (SRS)3B6U   
PDB (PDBSum)3B6U   
PDB (IMB)3B6U   
PDB (RSDB)3B6U   
Structural Biology KnowledgeBase3B6U   
SCOP (Structural Classification of Proteins)3B6U   
CATH (Classification of proteins structures)3B6U   
SuperfamilyO15066
Human Protein AtlasENSG00000101350
Peptide AtlasO15066
HPRD04781
IPIIPI00004533   IPI00909987   
Protein Interaction databases
DIP (DOE-UCLA)O15066
IntAct (EBI)O15066
FunCoupENSG00000101350
BioGRIDKIF3B
STRING (EMBL)KIF3B
ZODIACKIF3B
Ontologies - Pathways
QuickGOO15066
Ontology : AmiGOmicrotubule motor activity  protein binding  ATP binding  centrosome  cytosol  plus-end kinesin complex  spindle microtubule  cilium  cilium  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  mitotic spindle organization  mitotic centrosome separation  determination of left/right symmetry  microtubule binding  anterograde axonal transport  ATP-dependent microtubule motor activity, plus-end-directed  microtubule cytoskeleton  membrane  kinesin II complex  Rho GTPase binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  intraciliary transport particle  positive regulation of cytokinesis  intraciliary transport involved in cilium assembly  extracellular exosome  plus-end-directed vesicle transport along microtubule  mitotic spindle assembly  ciliary tip  axon cytoplasm  
Ontology : EGO-EBImicrotubule motor activity  protein binding  ATP binding  centrosome  cytosol  plus-end kinesin complex  spindle microtubule  cilium  cilium  retrograde vesicle-mediated transport, Golgi to ER  microtubule-based movement  mitotic spindle organization  mitotic centrosome separation  determination of left/right symmetry  microtubule binding  anterograde axonal transport  ATP-dependent microtubule motor activity, plus-end-directed  microtubule cytoskeleton  membrane  kinesin II complex  Rho GTPase binding  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  intraciliary transport particle  positive regulation of cytokinesis  intraciliary transport involved in cilium assembly  extracellular exosome  plus-end-directed vesicle transport along microtubule  mitotic spindle assembly  ciliary tip  axon cytoplasm  
NDEx NetworkKIF3B
Atlas of Cancer Signalling NetworkKIF3B
Wikipedia pathwaysKIF3B
Orthology - Evolution
OrthoDB9371
GeneTree (enSembl)ENSG00000101350
Phylogenetic Trees/Animal Genes : TreeFamKIF3B
HOVERGENO15066
HOGENOMO15066
Homologs : HomoloGeneKIF3B
Homology/Alignments : Family Browser (UCSC)KIF3B
Gene fusions - Rearrangements
Fusion : MitelmanKIF3B/NINL [20q11.21/20p11.21]  
Fusion : MitelmanPAX5/KIF3B [9p13.2/20q11.21]  [dic(9;20)(p13;q11)]  
Fusion: TCGAKIF3B 20q11.21 NINL 20p11.21 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF3B
dbVarKIF3B
ClinVarKIF3B
1000_GenomesKIF3B 
Exome Variant ServerKIF3B
ExAC (Exome Aggregation Consortium)KIF3B (select the gene name)
Genetic variants : HAPMAP9371
Genomic Variants (DGV)KIF3B [DGVbeta]
DECIPHERKIF3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF3B 
Mutations
ICGC Data PortalKIF3B 
TCGA Data PortalKIF3B 
Broad Tumor PortalKIF3B
OASIS PortalKIF3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch KIF3B
DgiDB (Drug Gene Interaction Database)KIF3B
DoCM (Curated mutations)KIF3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF3B (select a term)
intoGenKIF3B
Cancer3DKIF3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603754   
Orphanet
MedgenKIF3B
Genetic Testing Registry KIF3B
NextProtO15066 [Medical]
TSGene9371
GENETestsKIF3B
Huge Navigator KIF3B [HugePedia]
snp3D : Map Gene to Disease9371
BioCentury BCIQKIF3B
ClinGenKIF3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9371
Chemical/Pharm GKB GenePA30103
Clinical trialKIF3B
Miscellaneous
canSAR (ICR)KIF3B (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF3B
EVEXKIF3B
GoPubMedKIF3B
iHOPKIF3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:21:35 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.