Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

KIF4A (kinesin family member 4A)

Identity

Alias (NCBI)KIF4
KIF4G1
MRX100
HGNC (Hugo) KIF4A
HGNC Alias symbKIF4-G1
KIF4
HSA271784
FLJ12530
FLJ12655
FLJ14204
FLJ20631
MRX100
HGNC Alias namechromokinesin
LocusID (NCBI) 24137
Atlas_Id 46090
Location Xq13.1  [Link to chromosome band Xq13]
Location_base_pair Starts at 70290104 and ends at 70420886 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KIF4A (Xq13.1) / ITGB3 (17q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

Nomenclature
HGNC (Hugo)KIF4A   13339
Cards
Entrez_Gene (NCBI)KIF4A    kinesin family member 4A
AliasesKIF4; KIF4G1; MRX100
GeneCards (Weizmann)KIF4A
Ensembl hg19 (Hinxton)ENSG00000090889 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000090889 [Gene_View]  ENSG00000090889 [Sequence]  chrX:70290104-70420886 [Contig_View]  KIF4A [Vega]
ICGC DataPortalENSG00000090889
TCGA cBioPortalKIF4A
AceView (NCBI)KIF4A
Genatlas (Paris)KIF4A
SOURCE (Princeton)KIF4A
Genetics Home Reference (NIH)KIF4A
Genomic and cartography
GoldenPath hg38 (UCSC)KIF4A  -     chrX:70290104-70420886 +  Xq13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF4A  -     Xq13.1   [Description]    (hg19-Feb_2009)
GoldenPathKIF4A - Xq13.1 [CytoView hg19]  KIF4A - Xq13.1 [CytoView hg38]
ImmunoBaseENSG00000090889
genome Data Viewer NCBIKIF4A [Mapview hg19]  
OMIM300521   300923   
Gene and transcription
Genbank (Entrez)AB208797 AF071592 AF179308 AF277375 AJ271784
RefSeq transcript (Entrez)NM_012310
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF4A
Alternative Splicing GalleryENSG00000090889
Gene ExpressionKIF4A [ NCBI-GEO ]   KIF4A [ EBI - ARRAY_EXPRESS ]   KIF4A [ SEEK ]   KIF4A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF4A [ Firebrowse - Broad ]
GenevisibleExpression of KIF4A in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)24137
GTEX Portal (Tissue expression)KIF4A
Human Protein AtlasENSG00000090889-KIF4A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95239   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95239  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95239
Splice isoforms : SwissVarO95239
PhosPhoSitePlusO95239
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    Kinesin_motor_dom_sf    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF4A
Blocks (Seattle)KIF4A
SuperfamilyO95239
Human Protein Atlas [tissue]ENSG00000090889-KIF4A [tissue]
Peptide AtlasO95239
HPRD06606
IPIIPI00178150   IPI00556059   IPI01009731   
Protein Interaction databases
DIP (DOE-UCLA)O95239
IntAct (EBI)O95239
BioGRIDKIF4A
STRING (EMBL)KIF4A
ZODIACKIF4A
Ontologies - Pathways
QuickGOO95239
Ontology : AmiGOmitotic cytokinesis  DNA binding  protein binding  ATP binding  nucleoplasm  chromosome  cytoplasm  cytosol  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  organelle organization  microtubule-based movement  mitotic spindle organization  anterograde axonal transport  membrane  nuclear matrix  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  mitotic spindle midzone assembly  axon cytoplasm  
Ontology : EGO-EBImitotic cytokinesis  DNA binding  protein binding  ATP binding  nucleoplasm  chromosome  cytoplasm  cytosol  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  organelle organization  microtubule-based movement  mitotic spindle organization  anterograde axonal transport  membrane  nuclear matrix  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  mitotic spindle midzone assembly  axon cytoplasm  
NDEx NetworkKIF4A
Atlas of Cancer Signalling NetworkKIF4A
Wikipedia pathwaysKIF4A
Orthology - Evolution
OrthoDB24137
GeneTree (enSembl)ENSG00000090889
Phylogenetic Trees/Animal Genes : TreeFamKIF4A
HOGENOMO95239
Homologs : HomoloGeneKIF4A
Homology/Alignments : Family Browser (UCSC)KIF4A
Gene fusions - Rearrangements
Fusion : QuiverKIF4A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF4A [hg38]
dbVarKIF4A
ClinVarKIF4A
MonarchKIF4A
1000_GenomesKIF4A 
Exome Variant ServerKIF4A
GNOMAD BrowserENSG00000090889
Varsome BrowserKIF4A
Genomic Variants (DGV)KIF4A [DGVbeta]
DECIPHERKIF4A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF4A 
Mutations
ICGC Data PortalKIF4A 
TCGA Data PortalKIF4A 
Broad Tumor PortalKIF4A
OASIS PortalKIF4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF4A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DKIF4A
Mutations and Diseases : HGMDKIF4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch KIF4A
DgiDB (Drug Gene Interaction Database)KIF4A
DoCM (Curated mutations)KIF4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF4A (select a term)
intoGenKIF4A
Cancer3DKIF4A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300521    300923   
Orphanet
DisGeNETKIF4A
MedgenKIF4A
Genetic Testing Registry KIF4A
NextProtO95239 [Medical]
GENETestsKIF4A
Target ValidationKIF4A
Huge Navigator KIF4A [HugePedia]
ClinGenKIF4A
Clinical trials, drugs, therapy
MyCancerGenomeKIF4A
Protein Interactions : CTD
Pharm GKB GenePA30105
PharosO95239
Clinical trialKIF4A
Miscellaneous
canSAR (ICR)KIF4A (select the gene name)
HarmonizomeKIF4A
DataMed IndexKIF4A
Probes
Litterature
PubMed91 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXKIF4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jan 1 18:21:23 CET 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.