Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIF4A (kinesin family member 4A)

Identity

Alias_symbol (synonym)KIF4-G1
KIF4
HSA271784
FLJ12530
FLJ12655
FLJ14204
FLJ20631
MRX100
Other aliasKIF4G1
HGNC (Hugo) KIF4A
LocusID (NCBI) 24137
Atlas_Id 46090
Location Xq13.1  [Link to chromosome band Xq13]
Location_base_pair Starts at 69509879 and ends at 69640774 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
KIF4A (Xq13.1) / ITGB3 (17q21.32)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF4A   13339
Cards
Entrez_Gene (NCBI)KIF4A  24137  kinesin family member 4A
AliasesKIF4; KIF4G1; MRX100
GeneCards (Weizmann)KIF4A
Ensembl hg19 (Hinxton)ENSG00000090889 [Gene_View]  chrX:69509879-69640774 [Contig_View]  KIF4A [Vega]
Ensembl hg38 (Hinxton)ENSG00000090889 [Gene_View]  chrX:69509879-69640774 [Contig_View]  KIF4A [Vega]
ICGC DataPortalENSG00000090889
TCGA cBioPortalKIF4A
AceView (NCBI)KIF4A
Genatlas (Paris)KIF4A
WikiGenes24137
SOURCE (Princeton)KIF4A
Genetics Home Reference (NIH)KIF4A
Genomic and cartography
GoldenPath hg19 (UCSC)KIF4A  -     chrX:69509879-69640774 +  Xq13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)KIF4A  -     Xq13.1   [Description]    (hg38-Dec_2013)
EnsemblKIF4A - Xq13.1 [CytoView hg19]  KIF4A - Xq13.1 [CytoView hg38]
Mapping of homologs : NCBIKIF4A [Mapview hg19]  KIF4A [Mapview hg38]
OMIM300521   300923   
Gene and transcription
Genbank (Entrez)AB208797 AF071592 AF179308 AF277375 AJ271784
RefSeq transcript (Entrez)NM_012310
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_016799 NT_011651 NW_004929443
Consensus coding sequences : CCDS (NCBI)KIF4A
Cluster EST : UnigeneHs.648326 [ NCBI ]
CGAP (NCI)Hs.648326
Alternative Splicing GalleryENSG00000090889
Gene ExpressionKIF4A [ NCBI-GEO ]   KIF4A [ EBI - ARRAY_EXPRESS ]   KIF4A [ SEEK ]   KIF4A [ MEM ]
Gene Expression Viewer (FireBrowse)KIF4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)24137
GTEX Portal (Tissue expression)KIF4A
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95239   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95239  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95239
Splice isoforms : SwissVarO95239
PhosPhoSitePlusO95239
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin-like_fam    Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF4A
DMDM Disease mutations24137
Blocks (Seattle)KIF4A
SuperfamilyO95239
Human Protein AtlasENSG00000090889
Peptide AtlasO95239
HPRD06606
IPIIPI00178150   IPI00556059   IPI01009731   
Protein Interaction databases
DIP (DOE-UCLA)O95239
IntAct (EBI)O95239
FunCoupENSG00000090889
BioGRIDKIF4A
STRING (EMBL)KIF4A
ZODIACKIF4A
Ontologies - Pathways
QuickGOO95239
Ontology : AmiGOmitotic cytokinesis  DNA binding  microtubule motor activity  protein binding  ATP binding  nucleoplasm  chromosome  cytoplasm  cytosol  kinesin complex  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  organelle organization  microtubule-based movement  microtubule binding  anterograde axonal transport  metabolic process  ATP-dependent microtubule motor activity, plus-end-directed  membrane  nuclear matrix  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  mitotic spindle midzone assembly  axon cytoplasm  
Ontology : EGO-EBImitotic cytokinesis  DNA binding  microtubule motor activity  protein binding  ATP binding  nucleoplasm  chromosome  cytoplasm  cytosol  kinesin complex  spindle microtubule  retrograde vesicle-mediated transport, Golgi to ER  organelle organization  microtubule-based movement  microtubule binding  anterograde axonal transport  metabolic process  ATP-dependent microtubule motor activity, plus-end-directed  membrane  nuclear matrix  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  mitotic spindle midzone assembly  axon cytoplasm  
NDEx NetworkKIF4A
Atlas of Cancer Signalling NetworkKIF4A
Wikipedia pathwaysKIF4A
Orthology - Evolution
OrthoDB24137
GeneTree (enSembl)ENSG00000090889
Phylogenetic Trees/Animal Genes : TreeFamKIF4A
HOVERGENO95239
HOGENOMO95239
Homologs : HomoloGeneKIF4A
Homology/Alignments : Family Browser (UCSC)KIF4A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF4A
dbVarKIF4A
ClinVarKIF4A
1000_GenomesKIF4A 
Exome Variant ServerKIF4A
ExAC (Exome Aggregation Consortium)KIF4A (select the gene name)
Genetic variants : HAPMAP24137
Genomic Variants (DGV)KIF4A [DGVbeta]
DECIPHER (Syndromes)X:69509879-69640774  ENSG00000090889
CONAN: Copy Number AnalysisKIF4A 
Mutations
ICGC Data PortalKIF4A 
TCGA Data PortalKIF4A 
Broad Tumor PortalKIF4A
OASIS PortalKIF4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch KIF4A
DgiDB (Drug Gene Interaction Database)KIF4A
DoCM (Curated mutations)KIF4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF4A (select a term)
intoGenKIF4A
Cancer3DKIF4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300521    300923   
Orphanet
MedgenKIF4A
Genetic Testing Registry KIF4A
NextProtO95239 [Medical]
TSGene24137
GENETestsKIF4A
Huge Navigator KIF4A [HugePedia]
snp3D : Map Gene to Disease24137
BioCentury BCIQKIF4A
ClinGenKIF4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD24137
Chemical/Pharm GKB GenePA30105
Clinical trialKIF4A
Miscellaneous
canSAR (ICR)KIF4A (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF4A
EVEXKIF4A
GoPubMedKIF4A
iHOPKIF4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:11:55 CET 2017

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