Atlas of Genetics and Cytogenetics in Oncology and Haematology


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KIF5C (kinesin family member 5C)

Identity

Other aliasCDCBM2
KINN
NKHC
NKHC-2
NKHC2
HGNC (Hugo) KIF5C
LocusID (NCBI) 3800
Atlas_Id 64928
Location 2q23.1  [Link to chromosome band 2q23]
Location_base_pair Starts at 148875223 and ends at 149026759 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KIF5C (2q23.1) / CASP1 (11q22.3)KIF5C (2q23.1) / GALNT13 (2q23.3)KIF5C (2q23.1) / KIF3C (2p23.3)
KIF5C (2q23.1) / SOD2 (6q25.3)KIF5C (2q23.1) / TTN (2q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)KIF5C   6325
Cards
Entrez_Gene (NCBI)KIF5C  3800  kinesin family member 5C
AliasesCDCBM2; KINN; NKHC; NKHC-2; 
NKHC2
GeneCards (Weizmann)KIF5C
Ensembl hg19 (Hinxton)ENSG00000168280 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168280 [Gene_View]  chr2:148875223-149026759 [Contig_View]  KIF5C [Vega]
ICGC DataPortalENSG00000168280
TCGA cBioPortalKIF5C
AceView (NCBI)KIF5C
Genatlas (Paris)KIF5C
WikiGenes3800
SOURCE (Princeton)KIF5C
Genetics Home Reference (NIH)KIF5C
Genomic and cartography
GoldenPath hg38 (UCSC)KIF5C  -     chr2:148875223-149026759 +  2q23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)KIF5C  -     2q23.1   [Description]    (hg19-Feb_2009)
EnsemblKIF5C - 2q23.1 [CytoView hg19]  KIF5C - 2q23.1 [CytoView hg38]
Mapping of homologs : NCBIKIF5C [Mapview hg19]  KIF5C [Mapview hg38]
OMIM604593   615282   
Gene and transcription
Genbank (Entrez)AA602178 AB011103 AB073396 AB209191 AF010146
RefSeq transcript (Entrez)NM_004522
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)KIF5C
Cluster EST : UnigeneHs.660699 [ NCBI ]
CGAP (NCI)Hs.660699
Alternative Splicing GalleryENSG00000168280
Gene ExpressionKIF5C [ NCBI-GEO ]   KIF5C [ EBI - ARRAY_EXPRESS ]   KIF5C [ SEEK ]   KIF5C [ MEM ]
Gene Expression Viewer (FireBrowse)KIF5C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3800
GTEX Portal (Tissue expression)KIF5C
Human Protein AtlasENSG00000168280-KIF5C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60282   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60282  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60282
Splice isoforms : SwissVarO60282
PhosPhoSitePlusO60282
Domaine pattern : Prosite (Expaxy)KINESIN_MOTOR_1 (PS00411)    KINESIN_MOTOR_2 (PS50067)   
Domains : Interpro (EBI)Kinesin_motor_CS    Kinesin_motor_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)Kinesin (PF00225)   
Domain families : Pfam (NCBI)pfam00225   
Domain families : Smart (EMBL)KISc (SM00129)  
Conserved Domain (NCBI)KIF5C
DMDM Disease mutations3800
Blocks (Seattle)KIF5C
SuperfamilyO60282
Human Protein Atlas [tissue]ENSG00000168280-KIF5C [tissue]
Peptide AtlasO60282
IPIIPI00028561   IPI00889664   IPI00654747   IPI01018634   
Protein Interaction databases
DIP (DOE-UCLA)O60282
IntAct (EBI)O60282
FunCoupENSG00000168280
BioGRIDKIF5C
STRING (EMBL)KIF5C
ZODIACKIF5C
Ontologies - Pathways
QuickGOO60282
Ontology : AmiGOmicrotubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  organelle organization  microtubule-based movement  axon guidance  microtubule binding  motor neuron axon guidance  protein localization  ATP-dependent microtubule motor activity, plus-end-directed  cytoskeleton-dependent intracellular transport  ciliary rootlet  neuron projection  mRNA transport  
Ontology : EGO-EBImicrotubule motor activity  protein binding  ATP binding  cytoplasm  kinesin complex  microtubule  organelle organization  microtubule-based movement  axon guidance  microtubule binding  motor neuron axon guidance  protein localization  ATP-dependent microtubule motor activity, plus-end-directed  cytoskeleton-dependent intracellular transport  ciliary rootlet  neuron projection  mRNA transport  
Pathways : KEGGDopaminergic synapse   
NDEx NetworkKIF5C
Atlas of Cancer Signalling NetworkKIF5C
Wikipedia pathwaysKIF5C
Orthology - Evolution
OrthoDB3800
GeneTree (enSembl)ENSG00000168280
Phylogenetic Trees/Animal Genes : TreeFamKIF5C
HOVERGENO60282
HOGENOMO60282
Homologs : HomoloGeneKIF5C
Homology/Alignments : Family Browser (UCSC)KIF5C
Gene fusions - Rearrangements
Tumor Fusion PortalKIF5C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerKIF5C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)KIF5C
dbVarKIF5C
ClinVarKIF5C
1000_GenomesKIF5C 
Exome Variant ServerKIF5C
ExAC (Exome Aggregation Consortium)ENSG00000168280
GNOMAD BrowserENSG00000168280
Genetic variants : HAPMAP3800
Genomic Variants (DGV)KIF5C [DGVbeta]
DECIPHERKIF5C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisKIF5C 
Mutations
ICGC Data PortalKIF5C 
TCGA Data PortalKIF5C 
Broad Tumor PortalKIF5C
OASIS PortalKIF5C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICKIF5C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDKIF5C
BioMutasearch KIF5C
DgiDB (Drug Gene Interaction Database)KIF5C
DoCM (Curated mutations)KIF5C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)KIF5C (select a term)
intoGenKIF5C
Cancer3DKIF5C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604593    615282   
Orphanet
DisGeNETKIF5C
MedgenKIF5C
Genetic Testing Registry KIF5C
NextProtO60282 [Medical]
TSGene3800
GENETestsKIF5C
Target ValidationKIF5C
Huge Navigator KIF5C [HugePedia]
snp3D : Map Gene to Disease3800
BioCentury BCIQKIF5C
ClinGenKIF5C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3800
Chemical/Pharm GKB GenePA30109
Clinical trialKIF5C
Miscellaneous
canSAR (ICR)KIF5C (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineKIF5C
EVEXKIF5C
GoPubMedKIF5C
iHOPKIF5C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:04:48 CET 2017

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